Rewriting the history of leishmaniasis in Sri Lanka: An untold story since 1904. (2022)
Journal Article
Nuwangi, H., Weerakoon, K., Agampodi, T., Price, H., Dikomitis, L., & Agampodi, S. (2022). Rewriting the history of leishmaniasis in Sri Lanka: An untold story since 1904. PLoS Neglected Tropical Diseases, e0010918 - ?. https://doi.org/10.1371/journal.pntd.0010918

Leishmaniasis is widely considered a disease that emerged in Sri Lanka in the 1990s. However, a comprehensive case report from 1904 suggests that the presence of Leishmaniasis was well demonstrated in Sri Lanka long before that. The Annual Administra... Read More about Rewriting the history of leishmaniasis in Sri Lanka: An untold story since 1904..

Alteration of the expression of sirtuins and var genes by heat shock in the malaria parasite Plasmodium falciparum (2022)
Journal Article
Anagu, L. O., Hulse, D. R., Horrocks, P. D., & Chakravorty, S. J. (2022). Alteration of the expression of sirtuins and var genes by heat shock in the malaria parasite Plasmodium falciparum. Molecular and Biochemical Parasitology, 111458 - 111458. https://doi.org/10.1016/j.molbiopara.2022.111458

Background
In Plasmodium falciparum the monoallelic expression of var virulence genes is regulated through epigenetic mechanisms. A study in the Gambia showed that an increase in var gene expression is associated with fever, high blood lactate with... Read More about Alteration of the expression of sirtuins and var genes by heat shock in the malaria parasite Plasmodium falciparum.

Blood biochemical parameters as predictors of disease severity and mortality in COVID-19 patients- an updated systematic review and meta-analysis (2021)
Other
Majid, A., Mishra, P., Parveen, R., Bajpai, R., Khan, M., & Agarwal, N. (2021). Blood biochemical parameters as predictors of disease severity and mortality in COVID-19 patients- an updated systematic review and meta-analysis

<h4>ABSTRACT</h4> <h4>Background</h4> The outbreak of coronavirus disease 2019 (COVID-19) has been rapidly spreading across the globe and poses a great risk to human health. Patients with abnormalities in laboratory parameters are more susceptible to... Read More about Blood biochemical parameters as predictors of disease severity and mortality in COVID-19 patients- an updated systematic review and meta-analysis.

A genome-wide association study suggests correlations of common genetic variants with peritoneal solute transfer rates in patients with kidney failure receiving peritoneal dialysis. (2021)
Journal Article
Davies, & Lambie. (2021). A genome-wide association study suggests correlations of common genetic variants with peritoneal solute transfer rates in patients with kidney failure receiving peritoneal dialysis. Kidney International, 1101-1111. https://doi.org/10.1016/j.kint.2021.05.037

Movement of solutes across the peritoneum allows for the use of peritoneal dialysis to treat kidney failure. However, there is a large inter-individual variability in the peritoneal solute transfer rate (PSTR). Here, we tested the hypothesis that com... Read More about A genome-wide association study suggests correlations of common genetic variants with peritoneal solute transfer rates in patients with kidney failure receiving peritoneal dialysis..

Mapping Gene-by-Gene Single-Nucleotide Variation in 8,535 Mycobacterium tuberculosis Genomes: a Resource To Support Potential Vaccine and Drug Development (2021)
Journal Article
Papakonstantinou, D., Dunn, S. J., Draper, S. J., Cunningham, A. F., O’Shea, M. K., & McNally, A. (2021). Mapping Gene-by-Gene Single-Nucleotide Variation in 8,535 Mycobacterium tuberculosis Genomes: a Resource To Support Potential Vaccine and Drug Development. mSphere, 6(2), https://doi.org/10.1128/msphere.01224-20

Tuberculosis (TB) is responsible for millions of deaths annually. More effective vaccines and new antituberculous drugs are essential to control the disease. Numerous genomic studies have advanced our knowledge about M. tuberculosis drug resistance,... Read More about Mapping Gene-by-Gene Single-Nucleotide Variation in 8,535 Mycobacterium tuberculosis Genomes: a Resource To Support Potential Vaccine and Drug Development.

Rapid implementation and validation of a cold-chain free SARS-CoV-2 diagnostic testing workflow to support surge capacity (2020)
Journal Article
Bosworth, A., Whalley, C., Poxon, C., Wanigasooriya, K., Pickles, O., Aldera, E. L., …Beggs, A. D. (in press). Rapid implementation and validation of a cold-chain free SARS-CoV-2 diagnostic testing workflow to support surge capacity. Journal of Clinical Virology, 128, Article 104469. https://doi.org/10.1016/j.jcv.2020.104469

Background In January 2020 reports of unidentified severe respiratory illness were described in Wuhan, China. A rapid expansion in cases affecting most countries around the globe led to major changes in the way people live their daily lives. In the U... Read More about Rapid implementation and validation of a cold-chain free SARS-CoV-2 diagnostic testing workflow to support surge capacity.

Comparison of cough plates and cough swabs for detecting respiratory pathogens in non-expectorating children with cystic fibrosis (2019)
Thesis
Kemball, B. M. H. (2019). Comparison of cough plates and cough swabs for detecting respiratory pathogens in non-expectorating children with cystic fibrosis. (Thesis). Keele University

Background
Cystic fibrosis (CF) is an autosomal recessive, multisystem disorder affecting ion transportation across epithelial membranes. Respiratory complications are the leading cause of morbidity and mortality and CF lung disease is characterised... Read More about Comparison of cough plates and cough swabs for detecting respiratory pathogens in non-expectorating children with cystic fibrosis.