Clinical and cost effectiveness of a corticosteroid injection versus exercise therapy for shoulder pain in general practice: protocol for a randomised controlled trial (SIX Study). (2021)
Journal Article
Van Der Windt. (2021). Clinical and cost effectiveness of a corticosteroid injection versus exercise therapy for shoulder pain in general practice: protocol for a randomised controlled trial (SIX Study). BMJ Open, e050101 - ?. https://doi.org/10.1136/bmjopen-2021-050101

INTRODUCTION: Shoulder pain is common and the prognosis is often unfavourable. Dutch guidelines on the treatment of shoulder pain in primary care recommend a corticosteroid injection or a referral to exercise therapy, if initial pain management fails... Read More about Clinical and cost effectiveness of a corticosteroid injection versus exercise therapy for shoulder pain in general practice: protocol for a randomised controlled trial (SIX Study)..

The cost-effectiveness of different approaches to exercise and corticosteroid injection for subacromial pain (impingement) syndrome. (2021)
Journal Article
Oppong, R., Jowett, S., Lewis, M., Roddy, E., Ogollah, R. O., Zwierska, I., Datta, P., Hall, A., Hay, E., Shufflebotham, J., Stevenson, K., Van Der Windt, D. A., Young, J., & Foster, N. E. (2021). The cost-effectiveness of different approaches to exercise and corticosteroid injection for subacromial pain (impingement) syndrome. Rheumatology, 60(9), 4175-4184. https://doi.org/10.1093/rheumatology/keaa903

OBJECTIVES: To determine whether physiotherapist-led exercise intervention and ultrasound-guided subacromial corticosteroid injection is cost-effective when compared with standard advice and exercise leaflet and unguided injection in patients with su... Read More about The cost-effectiveness of different approaches to exercise and corticosteroid injection for subacromial pain (impingement) syndrome..

Moderators of the effects of therapeutic exercise for people with knee and hip osteoarthritis: A systematic review of sub-group analyses from randomised controlled trials (2020)
Journal Article
Quicke, J., Runhaar, J., Van Der Windt, D., Healey, E., Foster, N., & Holden, M. (2020). Moderators of the effects of therapeutic exercise for people with knee and hip osteoarthritis: A systematic review of sub-group analyses from randomised controlled trials. Osteoarthritis and Cartilage Open, 2(4), Article 100113. https://doi.org/10.1016/j.ocarto.2020.100113

Objective
1) To identify potential moderators of the effect of therapeutic exercise explored in randomised controlled trials (RCTs) of knee and hip osteoarthritis (OA); 2) summarise the extent, strength and quality of evidence reported for moderator... Read More about Moderators of the effects of therapeutic exercise for people with knee and hip osteoarthritis: A systematic review of sub-group analyses from randomised controlled trials.

Evidence-based treatment recommendations for neck and low back pain across Europe: A systematic review of guidelines. (2020)
Journal Article
Corp, N., Mansell, G., Stynes, S., Wynne-Jones, G., Morsø, L., Hill, J., & Van Der Windt, D. (2021). Evidence-based treatment recommendations for neck and low back pain across Europe: A systematic review of guidelines. European Journal of Pain, 25(2), https://doi.org/10.1002/ejp.1679

Background and objective: This systematic review synthesised evidence from European neck and low back pain (NLBP) clinical practice guidelines (CPGs) to identify recommended treatment options for use across Europe. Databases and Data Treatment: Compr... Read More about Evidence-based treatment recommendations for neck and low back pain across Europe: A systematic review of guidelines..

Optimising outcomes of exercise and corticosteroid injection in patients with subacromial pain (impingement) syndrome: a factorial randomised trial. (2020)
Journal Article
Roddy, E., Ogollah, R., Oppong, R., Zwierska, I., Datta, P., Hall, A., Hay, E., Jackson, S., Jowett, S., Lewis, M., Shufflebotham, J., Stevenson, K., Van Der Windt, D., Young, J., & Foster, N. (2020). Optimising outcomes of exercise and corticosteroid injection in patients with subacromial pain (impingement) syndrome: a factorial randomised trial. British Journal of Sports Medicine, 55(5), https://doi.org/10.1136/bjsports-2019-101268

OBJECTIVES: To compare the clinical effectiveness of (1) physiotherapist-led exercise versus an exercise leaflet, and (2) ultrasound-guided subacromial corticosteroid injection versus unguided injection for pain and function in subacromial pain (form... Read More about Optimising outcomes of exercise and corticosteroid injection in patients with subacromial pain (impingement) syndrome: a factorial randomised trial..

A Systematic Review and Evidence Synthesis of Non-Medical Triage, Self-Referral and Direct Access Services for Patients with Musculoskeletal Pain. (2020)
Journal Article
Babatunde, O., Bishop, A., Cottrell, E., Jordan, J., Corp, N., Corp, N., Humphries, K., Hadley-Barrows, T., L. Huntley, A., & Van Der Windt, D. (2020). A Systematic Review and Evidence Synthesis of Non-Medical Triage, Self-Referral and Direct Access Services for Patients with Musculoskeletal Pain. PloS one, https://doi.org/10.1371/journal.pone.0235364

Introduction
The demand for musculoskeletal (MSK) care is rising, and is a growing challenge for general practice. Direct access to physiotherapy and other healthcare services may offer appropriate care for MSK pain patients but there is uncertainty... Read More about A Systematic Review and Evidence Synthesis of Non-Medical Triage, Self-Referral and Direct Access Services for Patients with Musculoskeletal Pain..

Computer-Based Stratified Primary Care for Musculoskeletal Consultations Compared With Usual Care: Study Protocol for the STarT MSK Cluster Randomized Controlled Trial. (2020)
Journal Article
Hill, J., Garvin, S., Chen, Y., Cooper, V., Wathall, S., Bartlam, B., Saunders, B., Lewis, M., Protheroe, J., Chudyk, A., Birkinshaw, H., Dunn, K. M., Jowett, S., Oppong, R., Hay, E., van der Windt, D., Mallen, C., & Foster, N. E. (2020). Computer-Based Stratified Primary Care for Musculoskeletal Consultations Compared With Usual Care: Study Protocol for the STarT MSK Cluster Randomized Controlled Trial. JMIR Research Protocols, 9(7), https://doi.org/10.2196/17939

BACKGROUND: Musculoskeletal (MSK) pain is a major cause of pain and disability. We previously developed a prognostic tool (STarT Back Tool) with demonstrated effectiveness in guiding primary care low back pain management by supporting decision-making... Read More about Computer-Based Stratified Primary Care for Musculoskeletal Consultations Compared With Usual Care: Study Protocol for the STarT MSK Cluster Randomized Controlled Trial..

Moderators of the effects of exercise for hip and knee osteoarthritis: a systematic review of subgroup analyses from randomised controlled trials (2020)
Journal Article
Van Der Windt, Healey, & Holden. (2020). Moderators of the effects of exercise for hip and knee osteoarthritis: a systematic review of subgroup analyses from randomised controlled trials. Osteoarthritis and Cartilage, https://doi.org/10.1016/j.joca.2020.02.263

Meta-analyses of randomised controlled trials (RCTs) of exercise interventions in people with knee and hip osteoarthritis (OA) provide strong evidence of, on average, a small-to-medium effect on pain and function outcomes compared to comparison inter... Read More about Moderators of the effects of exercise for hip and knee osteoarthritis: a systematic review of subgroup analyses from randomised controlled trials.

Stratified primary care versus non-stratified care for musculoskeletal pain: findings from the STarT MSK feasibility and pilot cluster randomized controlled trial (2020)
Journal Article
Hill, J., Garvin, S., Chen, Y., Cooper, V., Wathall, S., Saunders, B., Lewis, A. M., Protheroe, J., Chudyk, A., Dunn, K., Hay, E., Van Der Windt, D., Mallen, C., & Foster, N. E. (2020). Stratified primary care versus non-stratified care for musculoskeletal pain: findings from the STarT MSK feasibility and pilot cluster randomized controlled trial. BMC Family Practice, 21, Article 30. https://doi.org/10.1186/s12875-019-1074-9

Background: Musculoskeletal (MSK) pain from the five most common presentations to primary care (back, neck, shoulder, knee or multi-site pain), where the majority of patients are managed, is a costly global health challenge. At present, first-line de... Read More about Stratified primary care versus non-stratified care for musculoskeletal pain: findings from the STarT MSK feasibility and pilot cluster randomized controlled trial.

Do comorbidities predict pain and function in knee osteoarthritis following an exercise intervention, and do they moderate the effect of exercise? Analyses of data from three randomized controlled trials. (2019)
Journal Article
Legha, A., Burke, D. L., Foster, N. E., Van Der Windt, D. A., Quicke, J. G., Healey, E. L., Runhaar, J., & Holden, M. A. (2020). Do comorbidities predict pain and function in knee osteoarthritis following an exercise intervention, and do they moderate the effect of exercise? Analyses of data from three randomized controlled trials. Musculoskeletal Care, 18(1), 3-11. https://doi.org/10.1002/msc.1425

BACKGROUND: Although exercise is a core treatment for people with knee osteoarthritis (OA), it is currently unknown whether those with additional comorbidities respond differently to exercise than those without. We explored whether comorbidities pred... Read More about Do comorbidities predict pain and function in knee osteoarthritis following an exercise intervention, and do they moderate the effect of exercise? Analyses of data from three randomized controlled trials..

Longitudinal validity of using digital hand photographs for assessing hand osteoarthritis progression over 7 years in community-dwelling older adults with hand pain (2019)
Journal Article
Marshall, M., Jonsson, H., Helgadottir, G. P., Nicholls, E., Myers, H., Jansen, V., & van der Windt, D. (2019). Longitudinal validity of using digital hand photographs for assessing hand osteoarthritis progression over 7 years in community-dwelling older adults with hand pain. BMC Musculoskeletal Disorders, 20, Article 484. https://doi.org/10.1186/s12891-019-2829-0

Background
To determine the longitudinal construct validity of assessing hand OA progression on digital photographs over 7?years compared with progression determined from radiographs, clinical features and change in symptoms.

Methods
Participant... Read More about Longitudinal validity of using digital hand photographs for assessing hand osteoarthritis progression over 7 years in community-dwelling older adults with hand pain.

Predictors of the effects of treatment for shoulder pain: protocol of an individual participant data meta-analysis (2019)
Journal Article
van der Windt, D. A., Burke, D. L., Babatunde, O., Hattle, M., McRobert, C., Littlewood, C., Wynne-Jones, G., Chesterton, L., van der Heijden, G. J., Winters, J. C., Rhon, D. I., Bennell, K., Roddy, E., Heneghan, C., Beard, D., Rees, J. L., & Riley, R. D. (2019). Predictors of the effects of treatment for shoulder pain: protocol of an individual participant data meta-analysis. Diagnostic and Prognostic Research, 15 -?. https://doi.org/10.1186/s41512-019-0061-x

Background
Shoulder pain is one of the most common presentations of musculoskeletal pain with a 1-month population prevalence of between 7 and 26%. The overall prognosis of shoulder pain is highly variable with 40% of patients reporting persistent p... Read More about Predictors of the effects of treatment for shoulder pain: protocol of an individual participant data meta-analysis.

The OMERACT Core Domain Set for Clinical Trials of Shoulder Disorders. (2019)
Journal Article
Ramiro, S., Page, M. J., Whittle, S. L., Huang, H., Verhagen, A. P., Beaton, D. E., Richards, P., Voshaar, M., Shea, B., Van Der Windt, D. A., Kopkow, C., Lenza, M., Jain, N. B., Richards, B., Hill, C., Gill, T. K., Koes, B., Foster, N. E., Conaghan, P. G., Smith, T., …Buchbinder, R. (2019). The OMERACT Core Domain Set for Clinical Trials of Shoulder Disorders. Journal of Rheumatology, 969-975. https://doi.org/10.3899/jrheum.181070

OBJECTIVE:
To reach consensus on the core domains to be included in a core domain set for clinical trials of shoulder disorders using the Outcome Measures in Rheumatology (OMERACT) Filter 2.1 Core Domain Set process.

METHODS:
At OMERACT 2018,... Read More about The OMERACT Core Domain Set for Clinical Trials of Shoulder Disorders..

The development and content of the vocational advice intervention and training package for the Study of Work And Pain (SWAP) trial (ISRCTN 52269669) (2019)
Journal Article
Sowden, G., Main, C., Van Der Windt, D., Burton, K., & Wynne-Jones, G. (2019). The development and content of the vocational advice intervention and training package for the Study of Work And Pain (SWAP) trial (ISRCTN 52269669). Journal of Occupational Rehabilitation, 29, 295-405. https://doi.org/10.1007/s10926-018-9799-1

Purpose:
There are substantial costs associated with sickness absence and struggling at work however existing services in the UK are largely restricted to those absent from work for greater than six months. This paper details the development of an... Read More about The development and content of the vocational advice intervention and training package for the Study of Work And Pain (SWAP) trial (ISRCTN 52269669).

The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial. (2018)
Journal Article
Chesterton, L. S., Blagojevic-Bucknall, M., Burton, C., Dziedzic, K. S., Davenport, G., Jowett, S. M., Myers, H. L., Oppong, R., Rathod-Mistry, T., van der Windt, D. A., Hay, E. M., & Roddy, E. (2018). The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial. The Lancet, 392(10156), 1423 - 1433. https://doi.org/10.1016/s0140-6736%2818%2931572-1

Background
To our knowledge, the comparative effectiveness of commonly used conservative treatments for carpal tunnel syndrome has not been evaluated previously in primary care. We aimed to compare the clinical and cost-effectiveness of night splint... Read More about The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial..

Diagnostic accuracy of diagnostic imaging for lumbar disc herniation in adults with low back pain or sciatica is unknown; a systematic review (2018)
Journal Article
Kim, J.-H., van Rijn, R. M., van Tulder, M. W., Koes, B. W., de Boer, M. R., Ginai, A. Z., Ostelo, R. W., van der Windt, D. A., & Verhagen, A. P. (2018). Diagnostic accuracy of diagnostic imaging for lumbar disc herniation in adults with low back pain or sciatica is unknown; a systematic review. Chiropractic & Manual Therapies, 25, Article 37. https://doi.org/10.1186/s12998-018-0207-x

Main text: We aim to summarize the available evidence on the diagnostic accuracy of imaging (index test) compared to surgery (reference test) for identifying lumbar disc herniation (LDH) in adult patients. For this systematic review we searched MEDLI... Read More about Diagnostic accuracy of diagnostic imaging for lumbar disc herniation in adults with low back pain or sciatica is unknown; a systematic review.

Trends in the prevalence, incidence and surgical management of carpal tunnel syndrome between 1993 and 2013: an observational analysis of UK primary care records (2018)
Journal Article
Burton, C., Chen, Y., Chesterton, L. S., & Van Der Windt, D. (2018). Trends in the prevalence, incidence and surgical management of carpal tunnel syndrome between 1993 and 2013: an observational analysis of UK primary care records. BMJ Open, Article e020166. https://doi.org/10.1136/bmjopen-2017-020166

OBJECTIVES: To describe the prevalence, incidence and surgical management of carpal tunnel syndrome (CTS), between 1993 and 2013, as recorded in the Clinical Practice Research Datalink (CPRD). DESIGN: We completed a series of cross-sectional epidemio... Read More about Trends in the prevalence, incidence and surgical management of carpal tunnel syndrome between 1993 and 2013: an observational analysis of UK primary care records.

Temporal Changes in Comorbidity Burden in Patients Having Percutaneous Coronary Intervention and Impact on Prognosis (2018)
Journal Article
Potts, J., Kwok, C., Ensor, J., Rashid, M., Kadam, U., Kinnaird, T., Curzen, N., Pancholy, S., Van Der Windt, D., Riley, R., Bagur, R., & Mamas, M. (2018). Temporal Changes in Comorbidity Burden in Patients Having Percutaneous Coronary Intervention and Impact on Prognosis. American Journal of Cardiology, 122(5), 712-722. https://doi.org/10.1016/j.amjcard.2018.05.003

This study aims to evaluate the impact of comorbidity burden on outcomes among patients who undergo percutaneous coronary intervention (PCI). We used the Nationwide Inpatient Sample to identify all PCI procedures undertaken in the United States betwe... Read More about Temporal Changes in Comorbidity Burden in Patients Having Percutaneous Coronary Intervention and Impact on Prognosis.

Subgrouping and TargetEd Exercise pRogrammes for knee and hip OsteoArthritis (STEER OA): a systematic review update and individual participant data meta-analysis protocol. (2017)
Journal Article
Van Der Windt, Holden, & Dziedzic. (2017). Subgrouping and TargetEd Exercise pRogrammes for knee and hip OsteoArthritis (STEER OA): a systematic review update and individual participant data meta-analysis protocol. BMJ Open, e018971 - ?. https://doi.org/10.1136/bmjopen-2017-018971

INTRODUCTION: Knee and hip osteoarthritis (OA) is a leading cause of disability worldwide. Therapeutic exercise is a recommended core treatment for people with knee and hip OA, however, the observed effect sizes for reducing pain and improving physic... Read More about Subgrouping and TargetEd Exercise pRogrammes for knee and hip OsteoArthritis (STEER OA): a systematic review update and individual participant data meta-analysis protocol..

Prognosis of sciatica and back-related leg pain in primary care: the ATLAS cohort (2017)
Journal Article
Konstantinou, K., Dunn, K., Ogollah, R., Lewis, M., Van Der Windt, D., Hay, E., & Study Team, A. (2017). Prognosis of sciatica and back-related leg pain in primary care: the ATLAS cohort. Spine Journal, 1030-1040. https://doi.org/10.1016/j.spinee.2017.10.071

Background Context
Evidence is lacking on the prognosis and prognostic factors of back-related leg pain and sciatica in patients seeing their primary care physicians. This evidence could guide timely appropriate treatment and referral decisions.... Read More about Prognosis of sciatica and back-related leg pain in primary care: the ATLAS cohort.