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Cost of coronary syndrome treated with percutaneous coronary intervention and 30-day unplanned readmission in the United States (2021)
Journal Article
Nolan, J., Mamas, M., Kwok, C. S., Amin, A. P., Shah, B., Kinnaird, T., …Bagur, R. (2021). Cost of coronary syndrome treated with percutaneous coronary intervention and 30-day unplanned readmission in the United States. Catheterization and Cardiovascular Interventions, 97(1), 80-93. https://doi.org/10.1002/ccd.28660

Objectives: This study aimed to examine the cost of coronary syndrome treated with percutaneous coronary intervention (PCI) and 30-day unplanned readmissions.

Background: There is limited understanding of the hospital cost of index PCI and 30-day... Read More about Cost of coronary syndrome treated with percutaneous coronary intervention and 30-day unplanned readmission in the United States.

Trial characteristics associated with under-enrolment of females in randomized controlled trials of heart failure with reduced ejection fraction: a systematic review. (2021)
Journal Article
Mamas, M. (2021). Trial characteristics associated with under-enrolment of females in randomized controlled trials of heart failure with reduced ejection fraction: a systematic review. https://doi.org/10.1002/ejhf.2034

AIMS: To evaluate temporal trends in the enrolment of females in randomized controlled trials (RCTs) of heart failure with reduced ejection fraction (HFrEF) published in high-impact journals, and assess RCT characteristics associated with under-enrol... Read More about Trial characteristics associated with under-enrolment of females in randomized controlled trials of heart failure with reduced ejection fraction: a systematic review..

Comparison of distal radial access versus standard transradial access in patients with smaller diameter radial Arteries(The distal radial versus transradial access in small transradial ArteriesStudy: D.A.T.A - S.T.A.R study). (2021)
Journal Article
Chugh, Y., Sasidhar Kanaparthy, N., Piplani, S., Chugh, S., Shroff, A., Vidovich, M., …Kumar Chugh, S. (2021). Comparison of distal radial access versus standard transradial access in patients with smaller diameter radial Arteries(The distal radial versus transradial access in small transradial ArteriesStudy: D.A.T.A - S.T.A.R study). Indian Heart Journal, 73(1), 26 - 34. https://doi.org/10.1016/j.ihj.2020.11.002

AIMS: To evaluate safety and efficacy of distal right radial access (DRRA) compared to right radial access (RRA), for coronary procedures, in patients with smaller diameter radial arteries (SDRA) (radial artery diameter (RAD) < 2.1 mm). METHODS AND R...

Place and causes of acute cardiovascular mortality during the COVID-19 pandemic (2021)
Journal Article
Mamas. (2021). Place and causes of acute cardiovascular mortality during the COVID-19 pandemic. Heart, 113-119. https://doi.org/10.1136/heartjnl-2020-317912

OBJECTIVE: To describe the place and causes of acute cardiovascular death during the COVID-19 pandemic. METHODS: Retrospective cohort of adult (age =18 years) acute cardiovascular deaths (n=5?87?225) in England and Wales, from 1 January 2014 to 30 Ju... Read More about Place and causes of acute cardiovascular mortality during the COVID-19 pandemic.

Calcium intake, calcium supplementation and cardiovascular disease and mortality in the British population: EPIC-norfolk prospective cohort study and meta-analysis. (2020)
Journal Article
Mamas. (2020). Calcium intake, calcium supplementation and cardiovascular disease and mortality in the British population: EPIC-norfolk prospective cohort study and meta-analysis. European Journal of Epidemiology, https://doi.org/10.1007/s10654-020-00710-8

The role of dietary calcium in cardiovascular disease prevention is unclear. We aimed to determine the association between calcium intake and incident cardiovascular disease and mortality. Data were extracted from the European Prospective Investigati... Read More about Calcium intake, calcium supplementation and cardiovascular disease and mortality in the British population: EPIC-norfolk prospective cohort study and meta-analysis..

Sex differences in distribution, management and outcomes of combined ischemic-bleeding risk following acute coronary syndrome (2020)
Journal Article
Rashid, & Mamas. (2020). Sex differences in distribution, management and outcomes of combined ischemic-bleeding risk following acute coronary syndrome. International Journal of Cardiology, https://doi.org/10.1016/j.ijcard.2020.12.063

Background
Risk factors for further bleeding and ischemic events after acute coronary syndrome (ACS) often overlap. Little is known about sex-based differences in the management and outcomes of ACS patients according to their combined bleeding-ische... Read More about Sex differences in distribution, management and outcomes of combined ischemic-bleeding risk following acute coronary syndrome.

Gout Pharmacotherapy in Cardiovascular Diseases: A Review of Utility and Outcomes. (2020)
Journal Article
Roddy, & Mamas. (2020). Gout Pharmacotherapy in Cardiovascular Diseases: A Review of Utility and Outcomes. American Journal of Cardiovascular Drugs, https://doi.org/10.1007/s40256-020-00459-1

Hyperuricemia and gout have been linked to an increased risk for cardiovascular (CV) disease, stroke, hypertension, heart failure, and chronic kidney disease, possibly through a proinflammatory milieu. However, not all the drugs used in gout treatmen... Read More about Gout Pharmacotherapy in Cardiovascular Diseases: A Review of Utility and Outcomes..

Place and causes of acute cardiovascular mortality during the COVID-19 pandemic. (2020)
Journal Article
Mamas. (2020). Place and causes of acute cardiovascular mortality during the COVID-19 pandemic. Heart, 113-119. https://doi.org/10.1101/2020.07.14.20153734

Objective. To describe the place and causes of acute cardiovascular death during the COVID-19 pandemic.
Methods. Retrospective cohort of adult (age =18 years) acute cardiovascular deaths (n=587,225) in England and Wales, 1st January 2014 to 30th Jun... Read More about Place and causes of acute cardiovascular mortality during the COVID-19 pandemic..

The LENT index predicts 30 day outcomes following hospitalization for heart failure (2020)
Journal Article
Mamas. (2020). The LENT index predicts 30 day outcomes following hospitalization for heart failure. ESC Heart Failure, https://doi.org/10.1002/ehf2.13109

AIMS: The LE index (Length of hospitalization plus number of Emergent visits =6 months) predicts 30 day all-cause readmission or death following hospitalization for heart failure (HF). We combined N-terminal pro-B type natriuretic peptide (NT-proBNP)... Read More about The LENT index predicts 30 day outcomes following hospitalization for heart failure.

Cardiac arrest and related mortality in emergency departments in the United States: Analysis of the nationwide emergency department sample. (2020)
Journal Article
Mamas. (2020). Cardiac arrest and related mortality in emergency departments in the United States: Analysis of the nationwide emergency department sample. Resuscitation, 166 - 173. https://doi.org/10.1016/j.resuscitation.2020.10.005

AIMS: The aim of this study is to analyse the causes of cardiac arrests (CA) in the emergency departments (ED) in the United States and their clinical outcomes according to whether they had a primary or a secondary diagnosis of CA. METHODS: Data from... Read More about Cardiac arrest and related mortality in emergency departments in the United States: Analysis of the nationwide emergency department sample..

Trends in sex-based differences in outcomes following coronary artery bypass grafting in the United States between 2004 and 2015 (2020)
Journal Article
Mamas. (2020). Trends in sex-based differences in outcomes following coronary artery bypass grafting in the United States between 2004 and 2015. International Journal of Cardiology, 42-48. https://doi.org/10.1016/j.ijcard.2020.07.039

Background
The present study sought to examine the trends of sex-based differences in clinical outcomes after coronary artery bypass grafting (CABG), an area in which the current evidence remains limited.
Methods
All US adults hospitalized for fir... Read More about Trends in sex-based differences in outcomes following coronary artery bypass grafting in the United States between 2004 and 2015.

Trends, management and outcomes of acute myocardial infarction in chronic liver disease. (2020)
Journal Article
Mamas. (2020). Trends, management and outcomes of acute myocardial infarction in chronic liver disease. International Journal of Clinical Practice, https://doi.org/10.1111/ijcp.13841

AIMS: There are limited data on the management and outcomes of chronic liver disease (CLD) patients presenting with acute myocardial infarction (AMI), particularly according to the subtype of CLD. METHODS: Using the Nationwide Inpatient Sample (2004-... Read More about Trends, management and outcomes of acute myocardial infarction in chronic liver disease..

The association between osteoarthritis and invasive treatment and clinical outcomes in 6.5 million patients presenting with acute myocardial infarction (2020)
Journal Article
Parmar, S., Mohamed, M., Wilkie, R., & Mamas, M. (2020). The association between osteoarthritis and invasive treatment and clinical outcomes in 6.5 million patients presenting with acute myocardial infarction. European Heart Journal, 41(S2), 1660 - 1660. https://doi.org/10.1093/ehjci/ehaa946.1660

Background
People with osteoarthritis (OA) have an increased risk of cardiovascular disease, including acute myocardial infarction (AMI). Despite OA being the most common joint condition and the fastest increasing major health condition, there is li... Read More about The association between osteoarthritis and invasive treatment and clinical outcomes in 6.5 million patients presenting with acute myocardial infarction.

Distribution of contemporary sensitivity troponin in the emergency department and relationship to 30-day mortality: The CHARIOT-ED substudy. (2020)
Journal Article
Mamas. (2020). Distribution of contemporary sensitivity troponin in the emergency department and relationship to 30-day mortality: The CHARIOT-ED substudy. Clinical Medicine, 528 - 534. https://doi.org/10.7861/clinmed.2020-0267

BACKGROUND: Contemporary sensitivity troponin (cs-cTn) concentrations above the upper limit of normal (ULN) are seen in a wide range of clinical conditions and evidence is growing that suggests cs-cTn may be a biomarker of future morbidity and mortal... Read More about Distribution of contemporary sensitivity troponin in the emergency department and relationship to 30-day mortality: The CHARIOT-ED substudy..

Demographic, Regional, and State-Level Trends of Mortality in Patients With Aortic Stenosis in United States, 2008 to 2018. (2020)
Journal Article
Mamas. (2020). Demographic, Regional, and State-Level Trends of Mortality in Patients With Aortic Stenosis in United States, 2008 to 2018. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, e017433 - ?. https://doi.org/10.1161/JAHA.120.017433

Background Aortic stenosis-related mortality might vary across demographic subsets, regions, and states in the United States. Methods and Results We reviewed the death certificate data from the Centers for Disease Control and Prevention Wide-Ranging... Read More about Demographic, Regional, and State-Level Trends of Mortality in Patients With Aortic Stenosis in United States, 2008 to 2018..

Safety and Efficacy of Coronary Intravascular Lithotripsy for Calcified Coronary Arteries – A Systematic Review and Meta-Analysis (2020)
Journal Article
Mamas. (2020). Safety and Efficacy of Coronary Intravascular Lithotripsy for Calcified Coronary Arteries – A Systematic Review and Meta-Analysis. Expert Review of Cardiovascular Therapy, https://doi.org/10.1080/14779072.2021.1845143

Objectives: Intravascular lithotripsy (IVL) clinical efficacy and safety in the treatment of calcified coronary artery disease (CAC) is not well known. We sought to assess IVL safety and efficacy in CAC.

Methods: A comprehensive online databases s... Read More about Safety and Efficacy of Coronary Intravascular Lithotripsy for Calcified Coronary Arteries – A Systematic Review and Meta-Analysis.

Transcatheter aortic valve replacement and percutaneous coronary intervention versus surgical aortic valve replacement and coronary artery bypass grafting in patients with severe aortic stenosis and concomitant coronary artery disease: A systematic review and meta-analysis. (2020)
Journal Article
Mamas, M. (2020). Transcatheter aortic valve replacement and percutaneous coronary intervention versus surgical aortic valve replacement and coronary artery bypass grafting in patients with severe aortic stenosis and concomitant coronary artery disease: A systematic review and meta-analysis. https://doi.org/10.1002/ccd.29110

OBJECTIVES: We performed a systematic review and meta-analysis to evaluate the early and midterm outcomes of patients who underwent surgical aortic valve replacement (SAVR) and coronary artery bypass grafting (CABG) against patients who had transcath... Read More about Transcatheter aortic valve replacement and percutaneous coronary intervention versus surgical aortic valve replacement and coronary artery bypass grafting in patients with severe aortic stenosis and concomitant coronary artery disease: A systematic review and meta-analysis..

Impact of COVID-19 on cardiac procedure activity in England and associated 30-day mortality (2020)
Journal Article
Mohamed, M. O., Banerjee, A., Clarke, S., de Belder, M., Patwala, A., Goodwin, A. T., …Mamas, M. (2021). Impact of COVID-19 on cardiac procedure activity in England and associated 30-day mortality. European Heart Journal - Quality of Care and Clinical Outcomes, 7(3), 247-256. https://doi.org/10.1093/ehjqcco/qcaa079

Background: Limited data exists on the impact of COVID-19 on national changes in cardiac procedure activity, including patient characteristics and clinical outcomes before and during the COVID-19 pandemic.

Methods and Results: All major cardiac pr... Read More about Impact of COVID-19 on cardiac procedure activity in England and associated 30-day mortality.

Trial characteristics associated with the underrepresentation of women as lead authors in heart failure clinical trials (2020)
Journal Article
Mamas. (2020). Trial characteristics associated with the underrepresentation of women as lead authors in heart failure clinical trials. Journal of the American College of Cardiology, 1919-1930. https://doi.org/10.1016/j.jacc.2020.08.062

Background
Clinical trials change practice in cardiology, and leading them requires research training, mentorship, sponsorship, and networking. Women report challenges in obtaining these opportunities.

Objectives
The purpose of this review was t... Read More about Trial characteristics associated with the underrepresentation of women as lead authors in heart failure clinical trials.