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Persistent back pain in emerging adults: an analysis of the 1970 British Birth Cohort Study (2018)
Thesis
Nell, M. (2018). Persistent back pain in emerging adults: an analysis of the 1970 British Birth Cohort Study. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/417946

Low back pain (LBP) is a common, often long-term problem which occurs at all stages of life from childhood to old age. This thesis focuses on persistent LBP in ‘emerging adulthood’ (18-29 years), a developmental stage characterised by delayed subscri... Read More about Persistent back pain in emerging adults: an analysis of the 1970 British Birth Cohort Study.

Epidemiology of neuropathic pain in primary care patients consulting with low back-related leg pain (2018)
Thesis
Harrisson, S. A. (2018). Epidemiology of neuropathic pain in primary care patients consulting with low back-related leg pain. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/412647

Neuropathic pain (pain caused by nerve damage) is considered challenging to manage. One of the most common neuropathic pain conditions is believed to be the presence of sciatica in low back-related leg pain (LBLP). A systematic review of the literatu... Read More about Epidemiology of neuropathic pain in primary care patients consulting with low back-related leg pain.

Prevalence of foot pain across an international consortium of population based cohorts. (2018)
Journal Article
Gates, L. S., Arden, N. K., Hannan, M. T., Roddy, E., Gill, T. K., Hill, C. L., …Golightly, Y. M. (2019). Prevalence of foot pain across an international consortium of population based cohorts. Arthritis Care and Research, 71(5), 661-670. https://doi.org/10.1002/acr.23829

OBJECTIVE:
Despite the potential burden of foot pain, some of the most fundamental epidemiological questions surrounding the foot remain poorly explored. The prevalence of foot pain has proved difficult to compare across existing studies due to var... Read More about Prevalence of foot pain across an international consortium of population based cohorts..

The frequency of remission and low disease activity in patients with rheumatoid arthritis, and their ability to identify people with low disability and normal quality of life (2018)
Journal Article
(2019). The frequency of remission and low disease activity in patients with rheumatoid arthritis, and their ability to identify people with low disability and normal quality of life. Seminars in Arthritis and Rheumatism, 49(1), 20-26. https://doi.org/10.1016/j.semarthrit.2018.12.006

Objective
Treat-to-target in rheumatoid arthritis (RA) recommends targeting remission, with low disease activity (LDA) being an alternative goal. When deciding to target remission or LDA, important considerations are the likelihood of attaining them... Read More about The frequency of remission and low disease activity in patients with rheumatoid arthritis, and their ability to identify people with low disability and normal quality of life.

Access site and outcomes for unprotected left main stem PCI: an analysis of the British Cardiovascular Intervention Society database (2018)
Journal Article
Mamas. (2018). Access site and outcomes for unprotected left main stem PCI: an analysis of the British Cardiovascular Intervention Society database. JACC. Cardiovascular interventions, 2480-2491. https://doi.org/10.1016/j.jcin.2018.09.035

Objectives
Using the British Cardiovascular Intervention Society percutaneous coronary intervention (PCI) database, temporal trends, predictors, and outcomes of radial access (RA) versus femoral access (FA) for unprotected left main stem percutaneou... Read More about Access site and outcomes for unprotected left main stem PCI: an analysis of the British Cardiovascular Intervention Society database.

Can the STarT Back Tool predict health-related quality of life and work ability after an acute/subacute episode with back or neck pain? A psychometric validation study in primary care. (2018)
Journal Article
Hill, J. (2018). Can the STarT Back Tool predict health-related quality of life and work ability after an acute/subacute episode with back or neck pain? A psychometric validation study in primary care. BMJ Open, https://doi.org/10.1136/bmjopen-2018-021748

OBJECTIVES: The predictive ability of the STarT Back Tool (SBT) has not yet been examined among acute/subacute back and/or neck pain in a primary care setting in respect to health-related quality of life (HRQoL) and work ability outcomes. The aim of... Read More about Can the STarT Back Tool predict health-related quality of life and work ability after an acute/subacute episode with back or neck pain? A psychometric validation study in primary care..

Association of Medication Intensity and Stages of Airflow Limitation With the Risk of Hospitalization or Death in Patients With Heart Failure and Chronic Obstructive Pulmonary Disease (2018)
Journal Article
Mamas. (2018). Association of Medication Intensity and Stages of Airflow Limitation With the Risk of Hospitalization or Death in Patients With Heart Failure and Chronic Obstructive Pulmonary Disease. Journal of the American Medical Association, https://doi.org/10.1001/jamanetworkopen.2018.5489

IMPORTANCE
In heart failure (HF), chronic obstructive pulmonary disease (COPD) increases the risk of poor outcomes, but the effect of COPD severity is unknown. This information is important for early intervention tailored to the highest-risk groups.... Read More about Association of Medication Intensity and Stages of Airflow Limitation With the Risk of Hospitalization or Death in Patients With Heart Failure and Chronic Obstructive Pulmonary Disease.

Auditory stimulation improves motor function and caretaker burden in children with cerebral palsy-A randomized double blind study (2018)
Journal Article
(2018). Auditory stimulation improves motor function and caretaker burden in children with cerebral palsy-A randomized double blind study. PloS one, https://doi.org/10.1371/journal.pone.0208792

Aim To investigate the impact of auditory stimulation on motor function in children with cerebral palsy (CP) and disabling hypertonia. Method 9 matched pairs (age: 7y5m, SD 4y1m; 13 boys; gross-motor-functional-classification-scale: median 4; manual-... Read More about Auditory stimulation improves motor function and caretaker burden in children with cerebral palsy-A randomized double blind study.

UNWARRANTED USE OF NEPHROTOXIC ANTIBIOTICS IN CHILDREN WITH CYSTIC FIBROSIS (2018)
Presentation / Conference
Gilchrist. (2018, December). UNWARRANTED USE OF NEPHROTOXIC ANTIBIOTICS IN CHILDREN WITH CYSTIC FIBROSIS. Presented at British Thoracic Society Winter Meeting 2018, QEII Centre, Broad Sanctuary, Westminster, London, England

Introduction As life expectancy of individuals with cystic fibrosis (CF) continues to increase, complications resulting from lifetime drug exposures and CF comorbidities are becoming more prevalent. An example of this is chronic kidney disease (CKD).... Read More about UNWARRANTED USE OF NEPHROTOXIC ANTIBIOTICS IN CHILDREN WITH CYSTIC FIBROSIS.

Development and validation of a clinical rule for recognition of early inflammatory arthritis (2018)
Journal Article
Mallen, C., & Hider, S. (2018). Development and validation of a clinical rule for recognition of early inflammatory arthritis. BMJ Open, https://doi.org/10.1136/bmjopen-2018-023552

Objectives
National and international guidelines recommend prompt referral of patients presenting with inflammatory arthritis (IA), but general practitioners (GPs) feel uncertain in their proficiency to detect synovitis through joint examination, th... Read More about Development and validation of a clinical rule for recognition of early inflammatory arthritis.

Marital status and risk of cardiovascular diseases: A systematic review and meta-analysis (2018)
Journal Article
Wong, C., Kwok, C., Narain, A., Gulati, M., Mihalidou, A., Wu, P., …Mamas, M. (2018). Marital status and risk of cardiovascular diseases: A systematic review and meta-analysis. Heart, 1937-1948. https://doi.org/10.1136/heartjnl-2018-313005

Background The influence of marital status on the incidence of cardiovascular disease (CVD) and prognosis after CVD is inconclusive. We systematically reviewed the literature to determine how marital status influences CVD and prognosis after CVD.... Read More about Marital status and risk of cardiovascular diseases: A systematic review and meta-analysis.

Association of comorbid burden with clinical outcomes after transcatheter aortic valve implantation (2018)
Journal Article
Mamas. (2018). Association of comorbid burden with clinical outcomes after transcatheter aortic valve implantation. Heart, 2058-2066. https://doi.org/10.1136/heartjnl-2018-313356

OBJECTIVES
To investigate the association of the CharlsonComorbidity Index (CCI) with clinical outcomes after transcatheter aortic valve implantation (TAVI).

BACKGROUND: Patients undergoing TAVI have high comorbid burden; however, there is limite... Read More about Association of comorbid burden with clinical outcomes after transcatheter aortic valve implantation.

Does alanyl-glutamine supplementation offer potential to improve peritoneal dialysate biocompatibility? (2018)
Journal Article
Davies. (2018). Does alanyl-glutamine supplementation offer potential to improve peritoneal dialysate biocompatibility?. Kidney International, 1050 -1052. https://doi.org/10.1016/j.kint.2018.09.012

Peritoneal dialysis technique survival remains challenging due to peritonitis and long-term alterations to peritoneal membrane function and integrity. Up to now, the development of less bio-incompatible dialysis solutions have not had a major impact... Read More about Does alanyl-glutamine supplementation offer potential to improve peritoneal dialysate biocompatibility?.

Gout severity, socioeconomic status and work absence: a cross-sectional study in primary care (2018)
Journal Article
Mallen, Roddy, & Muller. (2018). Gout severity, socioeconomic status and work absence: a cross-sectional study in primary care. Arthritis Care and Research, 1822-1828. https://doi.org/10.1002/acr.23562

Objective
To examine the association between gout severity and socioeconomic status (SES) and gout severity and work absence.

Methods
Postal questionnaires were sent to adult patients who were registered with 20 general practices and who had co... Read More about Gout severity, socioeconomic status and work absence: a cross-sectional study in primary care.

Age Related Changes in Femoral Head Trabecular Architecture (2018)
Journal Article
Greenwood, C., Clement, J., Dicken, A., Evans, J., Lyburn, I., Martin, R., …Rogers, K. (2018). Age Related Changes in Femoral Head Trabecular Architecture. Aging and Disease, 9(6), 976-987. https://doi.org/10.14336/AD.2018.0124

Osteoporosis is a prevalent bone condition, characterised by low bone mineral density and increased fracture risk. Currently, the gold standard for identifying osteoporosis and increased fracture risk is through quantification of bone mineral density... Read More about Age Related Changes in Femoral Head Trabecular Architecture.

Secular trends in work disability and its relationship to musculoskeletal pain and mental health: a time-trend analysis using five cross-sectional surveys (2002-2010) in the general population. (2018)
Journal Article
Wynne-Jones, G., Chen, Y., Croft, P., Peat, G., Wilkie, R., Jordan, K., & Petersson, I. F. (2018). Secular trends in work disability and its relationship to musculoskeletal pain and mental health: a time-trend analysis using five cross-sectional surveys (2002-2010) in the general population. Occupational and Environmental Medicine, 877-883. https://doi.org/10.1136/oemed-2018-105171

OBJECTIVES: International evidence suggests that rates of inability to work because of illness can change over time. We hypothesised that one reason for this is that the link between inability to work and common illnesses, such as musculoskeletal pai... Read More about Secular trends in work disability and its relationship to musculoskeletal pain and mental health: a time-trend analysis using five cross-sectional surveys (2002-2010) in the general population..

Effect of external fixation rod coupling in computed tomography. (2018)
Journal Article
Peña-Solórzano, C., Dimmock, M., Albrecht, D., Paganin, D., Bassed, R., Klein, M., & Harris, P. (2018). Effect of external fixation rod coupling in computed tomography. Strategies in Trauma and Limb Reconstruction, 137 - 149. https://doi.org/10.1007/s11751-018-0318-x

External fixation is a common tool in the treatment of complex fractures, correction of limb deformity, and salvage arthrodesis. These devices typically incorporate radio-opaque metal rods/struts connected at varying distances and orientations betwee... Read More about Effect of external fixation rod coupling in computed tomography..

Outcomes Following Percutaneous Coronary Intervention (PCI) in Non-ST-segment Elevation Myocardial Infarction Patients with Coronary Artery Bypass Grafts (2018)
Journal Article
Shoaib, A., Kinnaird, T., Curzen, N., Kontopantelis, E., Ludman, P., de Belder, M., …Mamas, M. (2018). Outcomes Following Percutaneous Coronary Intervention (PCI) in Non-ST-segment Elevation Myocardial Infarction Patients with Coronary Artery Bypass Grafts. Circulation: Cardiovascular Interventions, 11(11), https://doi.org/10.1161/circinterventions.118.006824

Background: There are limited data on outcomes of patients with previous CABG presenting with NSTEMI undergoing PCI. We compare clinical characteristics and outcomes in NSTEMI patients undergoing PCI with or without prior CABG surgery in a national c... Read More about Outcomes Following Percutaneous Coronary Intervention (PCI) in Non-ST-segment Elevation Myocardial Infarction Patients with Coronary Artery Bypass Grafts.