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Laparoscopic ablation or excision with helium thermal coagulator versus electrodiathermy for the treatment of mild-to-moderate endometriosis: randomised controlled trial (2020)
Journal Article
Misra, G., Sim, J., Jerreat, S., Coia, T., Ritchie, J., O'Brien, S., …El-Gizawy, Z. (2020). Laparoscopic ablation or excision with helium thermal coagulator versus electrodiathermy for the treatment of mild-to-moderate endometriosis: randomised controlled trial. BJOG: An International Journal of Obstetrics and Gynaecology, 127(12), 1528-1535. https://doi.org/10.1111/1471-0528.16279

OBJECTIVE: To compare electrodiathermy with helium thermal coagulation in laparoscopic treatment of mild-to-moderate endometriosis. DESIGN: Parallel-group randomised controlled trial. SETTING: A UK endometriosis centre. POPULATION: Non-pregnant women... Read More about Laparoscopic ablation or excision with helium thermal coagulator versus electrodiathermy for the treatment of mild-to-moderate endometriosis: randomised controlled trial.

Pictorial methods to assess heavy menstrual bleeding in research and clinical practice: a systematic literature review (2020)
Journal Article
(2020). Pictorial methods to assess heavy menstrual bleeding in research and clinical practice: a systematic literature review. BMC Women's Health, 24 - 24. https://doi.org/10.1186/s12905-020-0887-y

Pictorial blood loss assessment charts (PBACs) represent the most widely used method to assess menstrual blood loss (MBL) in clinical trials. The aims of this review were to: (1) determine the diagnostic accuracy of PBACs that have been validated aga... Read More about Pictorial methods to assess heavy menstrual bleeding in research and clinical practice: a systematic literature review.

Obstetrics and Gynecological History (2020)
Journal Article
Park, K., Wu, P., & Gulati, M. (2020). Obstetrics and Gynecological History. JACC: Case Reports, 2(1), 161 - 163. https://doi.org/10.1016/j.jaccas.2019.11.035

Atherosclerotic cardiovascular disease (ASCVD) remains a significant cause of morbidity and mortality in women, with event rates rising particularly in young women. Women are disproportionately affected by traditional cardiovascular (CV) risk factors... Read More about Obstetrics and Gynecological History.

Obstetrics and Gynecologic History - A Missed Opportunity for Cardiovascular Risk Assessment (2020)
Journal Article
Wu. (2020). Obstetrics and Gynecologic History - A Missed Opportunity for Cardiovascular Risk Assessment. https://doi.org/10.1016/j.jaccas.2019.11.035

Atherosclerotic cardiovascular disease (ASCVD) remains a significant cause of morbidity and mortality in women, with the event rates particularly rising in young women. Women are disproportionately affected by traditional cardiovascular (CV) risk fac... Read More about Obstetrics and Gynecologic History - A Missed Opportunity for Cardiovascular Risk Assessment.

Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial (2019)
Journal Article
Wu. (2019). Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial. The Lancet, 394(10204), 1181 - 1190. https://doi.org/10.1016/S0140-6736%2819%2931963-4

BACKGROUND: In women with late preterm pre-eclampsia, the optimal time to initiate delivery is unclear because limitation of maternal disease progression needs to be balanced against infant complications. The aim of this trial was to determine whethe... Read More about Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial.

Chorionic and amniotic membrane-derived stem cells have distinct, and gestational diabetes mellitus independent, proliferative, differentiation, and immunomodulatory capacities (2019)
Journal Article
Wu. (2019). Chorionic and amniotic membrane-derived stem cells have distinct, and gestational diabetes mellitus independent, proliferative, differentiation, and immunomodulatory capacities. Stem Cell Research, 40, Article 101537. https://doi.org/10.1016/j.scr.2019.101537

Placental membrane-derived mesenchymal stem cells (MSCs), with the advantages of being non-invasive and having fewer ethical issues, are a promising source for cell therapy. Gestational diabetes (GDM) alters the uterine environment and may affect the... Read More about Chorionic and amniotic membrane-derived stem cells have distinct, and gestational diabetes mellitus independent, proliferative, differentiation, and immunomodulatory capacities.

Prediction of pre-eclampsia: review of reviews. (2019)
Journal Article
(2019). Prediction of pre-eclampsia: review of reviews. Ultrasound in Obstetrics & Gynecology, 16. https://doi.org/10.1002/uog.20117

OBJECTIVE:
Primary studies and systematic reviews provide varied accuracy estimates for prediction of pre-eclampsia. We undertook a review of published systematic reviews to collate published evidence on the ability of available tests to predict pr... Read More about Prediction of pre-eclampsia: review of reviews..

First trimester ultrasound measurements and maternal serum biomarkers as prognostic factors in monochorionic twins: a cohort study (2019)
Journal Article
(2019). First trimester ultrasound measurements and maternal serum biomarkers as prognostic factors in monochorionic twins: a cohort study. Diagnostic and Prognostic Research, https://doi.org/10.1186/s41512-019-0054-9

Background: Monochorionic twin pregnancies are high-risk of adverse outcomes, but it is not possible to predict which pregnancies will develop complications. The aim of the study was to evaluate, in monochorionic twin pregnancies, whether first trime... Read More about First trimester ultrasound measurements and maternal serum biomarkers as prognostic factors in monochorionic twins: a cohort study.

Empirical comparison of univariate and multivariate meta-analysis in Cochrane Pregnancy and Childbirth reviews with multiple binary outcomes (2019)
Journal Article
(2019). Empirical comparison of univariate and multivariate meta-analysis in Cochrane Pregnancy and Childbirth reviews with multiple binary outcomes. Research Synthesis Methods, https://doi.org/10.1002/jrsm.1353

Background: Multivariate meta-analysis (MVMA) jointly synthesise effects for multiple correlated outcomes. The MVMA model is potentially more difficult and time-consuming to apply than univariate models, so if its use makes little difference to param... Read More about Empirical comparison of univariate and multivariate meta-analysis in Cochrane Pregnancy and Childbirth reviews with multiple binary outcomes.

A systematic review of methods to measure menstrual blood loss (2018)
Journal Article
(2018). A systematic review of methods to measure menstrual blood loss. BMC Women's Health, https://doi.org/10.1186/s12905-018-0627-8

Background
Since the publication over 50 years ago of the alkaline hematin method for quantifying menstrual blood loss (MBL) many new approaches have been developed to assess MBL. The aim of this systematic review is to determine for methods of meas... Read More about A systematic review of methods to measure menstrual blood loss.

Changes in advanced glycation content, structural and mechanical properties of vaginal tissue during pregnancy and in prolapse (2018)
Thesis
Weli, H. K. (2018). Changes in advanced glycation content, structural and mechanical properties of vaginal tissue during pregnancy and in prolapse. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/411339

Introduction: Pelvic organ prolapse is present in up to 50% of women. It is commoner in older women, often above 50 years of age and associated with hormonal e.g. oestrogen decline, and stiffer vaginal tissue. Pregnancy, on the contrary is a physiolo... Read More about Changes in advanced glycation content, structural and mechanical properties of vaginal tissue during pregnancy and in prolapse.

Preterm birth and maternal cardiovascular outcomes: a systematic review and meta-analysis (2018)
Journal Article
Mamas. (2018). Preterm birth and maternal cardiovascular outcomes: a systematic review and meta-analysis. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, https://doi.org/10.1161/JAHA.117.007809

Background
Preterm delivery (<37 weeks gestational age) affects 11% of all pregnancies, but data are conflicting whether preterm birth is associated with long-term adverse maternal cardiovascular outcomes. We aimed to systematically evaluate and sum...

Improving postpartum care delivery and uptake by implementing context specific interventions in four countries in Africa: a realist evaluation of the Missed Opportunities in Maternal and Infant Health (MOMI) project (2017)
Journal Article
(2017). Improving postpartum care delivery and uptake by implementing context specific interventions in four countries in Africa: a realist evaluation of the Missed Opportunities in Maternal and Infant Health (MOMI) project. BMJ Global Health, https://doi.org/10.1136/bmjgh-2017-000408

Postpartum care (PPC) has remained relatively neglected in many interventions designed to improve maternal and neonatal health in sub-Saharan Africa. The Missed Opportunities in Maternal and Infant Health project developed and implemented a context-s... Read More about Improving postpartum care delivery and uptake by implementing context specific interventions in four countries in Africa: a realist evaluation of the Missed Opportunities in Maternal and Infant Health (MOMI) project.

Identification and evaluation of anticancer compounds from three Nigerian plants used in traditional medicines (2017)
Presentation / Conference
Rosa Johnson-Ajinwo, O., Richardson, A., & Li, W. (2017, September). Identification and evaluation of anticancer compounds from three Nigerian plants used in traditional medicines. Presented at IUPHAR, Aberdeen

Ovarian cancer is the second leading cause of death among women in the gynaecological category of cancers. The current post surgery treatment which involves the use of platinum-based therapy with its attendant adverse drug-resistance often results in... Read More about Identification and evaluation of anticancer compounds from three Nigerian plants used in traditional medicines.

Association of maternal serum PAPP-A levels, nuchal translucency and crown rump length in first trimester with adverse pregnancy outcomes: Retrospective cohort study. (2017)
Journal Article
(2017). Association of maternal serum PAPP-A levels, nuchal translucency and crown rump length in first trimester with adverse pregnancy outcomes: Retrospective cohort study. Prenatal Diagnosis, 705-711. https://doi.org/10.1002/pd.5069

OBJECTIVE: Are first trimester serum pregnancy-associated plasma protein-A (PAPP-A), nuchal translucency (NT) and crown rump length (CRL) prognostic factors for adverse pregnancy outcomes? METHOD: Retrospective cohort women, singleton pregnancies (UK... Read More about Association of maternal serum PAPP-A levels, nuchal translucency and crown rump length in first trimester with adverse pregnancy outcomes: Retrospective cohort study..

Laparoscopic excision versus ablation for endometriosis-associated pain - Updated systematic review and meta-analysis. (2017)
Journal Article
(2017). Laparoscopic excision versus ablation for endometriosis-associated pain - Updated systematic review and meta-analysis. Journal of Minimally Invasive Gynecology, 747-756. https://doi.org/10.1016/j.jmig.2017.04.008

The aim of the study is to update the evidence on surgical management of endometriosis associated pain - does laparoscopic excision offers any benefits over laparoscopic ablation? This is a systematic review and meta-analysis, where we searched MEDLI... Read More about Laparoscopic excision versus ablation for endometriosis-associated pain - Updated systematic review and meta-analysis..

Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy (2017)
Journal Article
Weli, H. K., Akhtar, R., Chang, Z., Li, W., Cooper, J., & Yang, Y. (2017). Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy. European Journal of Obstetrics and Gynecology and Reproductive Biology, 78-85. https://doi.org/10.1016/j.ejogrb.2017.04.037

Objectives
Non-enzymatic glycation is closely associated with altered mechanical properties of connective tissue. Pregnancy, marked with high levels of female hormones, confers unique alteration to the mechanical properties of pelvic connective tiss... Read More about Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy.

Prediction of complications in early-onset pre-eclampsia (PREP): development and external multinational validation of prognostic models (2017)
Journal Article
(2017). Prediction of complications in early-onset pre-eclampsia (PREP): development and external multinational validation of prognostic models. BMC Medicine, 68 -?. https://doi.org/10.1186/s12916-017-0827-3

BACKGROUND: Unexpected clinical deterioration before 34 weeks gestation is an undesired course in early-onset pre-eclampsia. To safely prolong preterm gestation, accurate and timely prediction of complications is required. METHOD: Women with confirme... Read More about Prediction of complications in early-onset pre-eclampsia (PREP): development and external multinational validation of prognostic models.

Non-contraceptive oestrogen-containing preparations for controlling symptoms of premenstrual syndrome. (2017)
Journal Article
(2017). Non-contraceptive oestrogen-containing preparations for controlling symptoms of premenstrual syndrome. Cochrane Database of Systematic Reviews, CD010503 - ?. https://doi.org/10.1002/14651858.CD010503.pub2

BACKGROUND: Premenstrual syndrome (PMS) is a psychological and somatic disorder of unknown aetiology, with symptoms typically including irritability, depression, mood swings, bloating, breast tenderness and sleep disturbances. About 3% to 10% of wome... Read More about Non-contraceptive oestrogen-containing preparations for controlling symptoms of premenstrual syndrome..