Genetic validation of Leishmania genes essential for amastigote survival in vivo using N-myristoyltransferase as a model
(2020)
Journal Article
Paape, D., Prendergast, C., Price, H., Doehl, J., & Smith, D. (2020). Genetic validation of Leishmania genes essential for amastigote survival in vivo using N-myristoyltransferase as a model. Parasites and Vectors, 13, Article 132. https://doi.org/10.1186/s13071-020-3999-1
Background: Proving that specifc genes are essential for the intracellular viability of Leishmania parasites within
macrophages remains a challenge for the identifcation of suitable targets for drug development. This is especially
evident in the ab...
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