Non-linear dose-response of aluminium hydroxide adjuvant particles: selective low dose neurotoxicity (2016)
Journal Article
(2016). Non-linear dose-response of aluminium hydroxide adjuvant particles: selective low dose neurotoxicity. Toxicology, 48-57. https://doi.org/10.1016/j.tox.2016.11.018

Abstract Aluminium (Al) oxyhydroxide (Alhydrogel®), the main adjuvant licensed for human and animal vaccines, consists of primary nanoparticles that spontaneously agglomerate. Concerns about its safety emerged following recognition of its unexpectedl... Read More about Non-linear dose-response of aluminium hydroxide adjuvant particles: selective low dose neurotoxicity.

Recombination events among virulence genes in malaria parasites are associated with G-quadruplex-forming DNA motifs (2016)
Journal Article
(2016). Recombination events among virulence genes in malaria parasites are associated with G-quadruplex-forming DNA motifs. BMC Genomics, 859. https://doi.org/10.1186/s12864-016-3183-3

Background Malaria parasites of the genus Plasmodium possess large hyper-variable families of antigen-encoding genes. These are often variantly-expressed and are major virulence factors for immune evasion and the maintenance of chronic infections. Re... Read More about Recombination events among virulence genes in malaria parasites are associated with G-quadruplex-forming DNA motifs.

Analysis of the dynamics of temporal relationships of neural activities using optical imaging data (2016)
Journal Article
(2016). Analysis of the dynamics of temporal relationships of neural activities using optical imaging data. Journal of Computational Neuroscience, 107-121. https://doi.org/10.1007/s10827-016-0630-8

The temporal relationship between the activities of neurons in biological neural systems is critically important for the correct delivery of the functionality of these systems. Fine measurement of temporal relationships of neural activities using mic... Read More about Analysis of the dynamics of temporal relationships of neural activities using optical imaging data.

Predicting microbiologically defined infection in febrile neutropenic episodes in children: global individual participant data multivariable meta-analysis. (2016)
Journal Article
(2016). Predicting microbiologically defined infection in febrile neutropenic episodes in children: global individual participant data multivariable meta-analysis. British journal of cancer, e17 - ?. https://doi.org/10.1038/bjc.2016.137

A Pilot Study of Ion - Molecule Reactions at Temperatures Relevant to the Atmosphere of Titan (2016)
Journal Article
(2016). A Pilot Study of Ion - Molecule Reactions at Temperatures Relevant to the Atmosphere of Titan. Origins of Life and Evolution of Biospheres, 533-538. https://doi.org/10.1007/s11084-016-9499-9

Reliable theoretical models of the chemical kinetics of the ionosphere of Saturn's moon, Titan, is highly dependent on the precision of the rates of the reactions of ambient ions with hydrocarbon molecules at relevant temperatures. A Variable Tempera... Read More about A Pilot Study of Ion - Molecule Reactions at Temperatures Relevant to the Atmosphere of Titan.

Crystal structure of a complex of Surfactant Protein D and Haemophilus influenzae lipopolysaccharide reveals shielding of core structures in SP-D resistant strains (2016)
Journal Article
Shrive, A., & Greenhough, T. (2016). Crystal structure of a complex of Surfactant Protein D and Haemophilus influenzae lipopolysaccharide reveals shielding of core structures in SP-D resistant strains. Infection and Immunity, 1585-1592. https://doi.org/10.1128/IAI.01239-15

The carbohydrate recognition domains (CRDs) of lung collectin surfactant protein D (SP-D) recognize sugar patterns on the surface of lung pathogens and promote phagocytosis. Using Haemophilus influenzae Eagan strains expressing well-characterized lip... Read More about Crystal structure of a complex of Surfactant Protein D and Haemophilus influenzae lipopolysaccharide reveals shielding of core structures in SP-D resistant strains.