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In vitro model of traumatic brain injury to screen neuro-regenerative biomaterials (2021)
Journal Article
Basit, R., Tzerakis, N., Jenkins, S., & Chari, D. M. (2021). In vitro model of traumatic brain injury to screen neuro-regenerative biomaterials. Materials Science and Engineering: C, 112253 - 112253. https://doi.org/10.1016/j.msec.2021.112253

Penetrating traumatic brain injury (pTBI) causes serious neurological deficits with no clinical regenerative therapies currently available. Tissue engineering strategies using biomaterial-based ‘structural bridges’ offer high potential to promote neu... Read More about In vitro model of traumatic brain injury to screen neuro-regenerative biomaterials.

characterizing ischaemic tolerance in rat pheochromocytoma (PC12) cells and primary rat neurons (2020)
Journal Article
Singh, A., Chow, O., Jenkins, S., Zhu, L., Rose, E., Astbury, K., & Chen, R. (2021). characterizing ischaemic tolerance in rat pheochromocytoma (PC12) cells and primary rat neurons. Neuroscience, 453, Article 17-31. https://doi.org/10.1016/j.neuroscience.2020.11.008

Preconditioning tissue with sublethal ischaemia or hypoxia can confer tolerance (protection) against subsequent ischaemic challenge. In vitro ischaemic preconditioning (IPC) is typically achieved through oxygen glucose deprivation (OGD), whereas hypo... Read More about characterizing ischaemic tolerance in rat pheochromocytoma (PC12) cells and primary rat neurons.