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Understanding self-harm behaviour in older adults: a systematic review and qualitative study (2019)
Thesis
Troya Bermeo, M. I. (2019). Understanding self-harm behaviour in older adults: a systematic review and qualitative study. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/415218

Two worldwide challenges served as a drive for this research: the reality of an ageing population and the identified need of supporting people who self-harm. Addressing self-harm has been increasingly prioritised due to its social, economic and healt... Read More about Understanding self-harm behaviour in older adults: a systematic review and qualitative study.

Time-saving opportunities in knee osteoarthritis: T2 mapping and structural imaging of the knee using a single 5-min MRI scan. (2019)
Journal Article
(2019). Time-saving opportunities in knee osteoarthritis: T2 mapping and structural imaging of the knee using a single 5-min MRI scan. European Radiology, 1 -10. https://doi.org/10.1007/s00330-019-06542-9

OBJECTIVES: To assess the discriminative power of a 5-min quantitative double-echo steady-state (qDESS) sequence for simultaneous T2 measurements of cartilage and meniscus, and structural knee osteoarthritis (OA) assessment, in a clinical OA populati... Read More about Time-saving opportunities in knee osteoarthritis: T2 mapping and structural imaging of the knee using a single 5-min MRI scan..

Exploring Patients' Experiences of Internet-Based Self-Management Support for Low Back Pain in Primary Care. (2019)
Journal Article
Geraghty, A. W. A., Roberts, L. C., Stanford, R., Hill, J. C., Yoganantham, D., Little, P., …Yardley, L. (2020). Exploring Patients' Experiences of Internet-Based Self-Management Support for Low Back Pain in Primary Care. Pain Medicine, 21(9), https://doi.org/10.1093/pm/pnz312

OBJECTIVE: We explored patients' experiences of using Internet-based self-management support for low back pain (LBP) in primary care, with and without physiotherapist telephone guidance. DESIGN: Exploratory descriptive qualitative study using themati... Read More about Exploring Patients' Experiences of Internet-Based Self-Management Support for Low Back Pain in Primary Care..

Virtual patient technology to educate pharmacists and pharmacy students on patient communication: a systematic review (2019)
Journal Article
Richardson, C. L., White, S., & Chapman, S. (2019). Virtual patient technology to educate pharmacists and pharmacy students on patient communication: a systematic review. BMJ Simulation and Technology Enhanced Learning, 332 - 338. https://doi.org/10.1136/bmjstel-2019-000514

Background Virtual patients (VPs) are a sub-type of healthcare simulation that have been underutilised in health education. Their use is increasing, but applications are varied, as are designs, definitions and evaluations. Previous reviews have been... Read More about Virtual patient technology to educate pharmacists and pharmacy students on patient communication: a systematic review.

How to quickly critically appraise a randomized control trial (2019)
Journal Article
(2019). How to quickly critically appraise a randomized control trial. Paediatrics and Child Health, 57-59. https://doi.org/10.1016/j.paed.2019.11.004

Being able to critically appraise scientific papers is an important skill. A thorough and methodical approach is necessary, particularly for peer-review purposes. However, it is also important to be able to do this quickly and efficiently. In some ci... Read More about How to quickly critically appraise a randomized control trial.

Volatiles of bacteria associated with parasitoid habitats elicit distinct olfactory responses in an aphid parasitoid and its hyperparasitoid (2019)
Journal Article
(2019). Volatiles of bacteria associated with parasitoid habitats elicit distinct olfactory responses in an aphid parasitoid and its hyperparasitoid. Functional Ecology, https://doi.org/10.1111/1365-2435.13503

To locate mating partners and essential resources such as food, oviposition sites and shelter, insects rely to a large extent on chemical cues. While most research has focused on cues derived from plants and insects, there is mounting evidence that i... Read More about Volatiles of bacteria associated with parasitoid habitats elicit distinct olfactory responses in an aphid parasitoid and its hyperparasitoid.

Enhancement of Deep Learning in Image Classification Performance Using Xception with the Swish Activation Function for Colorectal Polyp Preliminary Screening (2019)
Journal Article
Jinsakul, N., Tsai, C., Tsai, C., & Wu, P. (2019). Enhancement of Deep Learning in Image Classification Performance Using Xception with the Swish Activation Function for Colorectal Polyp Preliminary Screening. Mathematics, 7(12), Article 1170. https://doi.org/10.3390/math7121170

One of the leading forms of cancer is colorectal cancer (CRC), which is responsible for increasing mortality in young people. The aim of this paper is to provide an experimental modification of deep learning of Xception with Swish and assess the poss... Read More about Enhancement of Deep Learning in Image Classification Performance Using Xception with the Swish Activation Function for Colorectal Polyp Preliminary Screening.

A standardization approach to compare treatment safety and effectiveness outcomes between clinical trials and real-world populations in psoriasis. (2019)
Journal Article
Yiu, Z., Mason, K., Barker, J., Hampton, P., McElhone, K., Smith, C., …Burden, A. (in press). A standardization approach to compare treatment safety and effectiveness outcomes between clinical trials and real-world populations in psoriasis. British Journal of Dermatology, 181(6), 1265 - 1271. https://doi.org/10.1111/bjd.17849

BACKGROUND: Patients recruited in randomized controlled trials (RCTs) for biologic therapies in psoriasis are not fully representative of the real-world psoriasis population. OBJECTIVES: Firstly, to investigate whether patient characteristics are ass... Read More about A standardization approach to compare treatment safety and effectiveness outcomes between clinical trials and real-world populations in psoriasis..

Identification of novel inhibitors for the tyrosyl-DNA-phosphodiesterase 1 (Tdp1) mutant SCAN1 using virtual screening. (2019)
Journal Article
Reynisson. (2019). Identification of novel inhibitors for the tyrosyl-DNA-phosphodiesterase 1 (Tdp1) mutant SCAN1 using virtual screening. Bioorganic and Medicinal Chemistry, 115234 - ?. https://doi.org/10.1016/j.bmc.2019.115234

Spinocerebellar ataxia syndrome with axonal neuropathy (SCAN1) is a debilitating neurological disease that is caused by the mutation the Tyrosyl-DNA phosphodiesterase 1 (TDP1) DNA repair enzyme. The crucial His493 in TDP1's binding site is replaced w... Read More about Identification of novel inhibitors for the tyrosyl-DNA-phosphodiesterase 1 (Tdp1) mutant SCAN1 using virtual screening..

Evaluating the impact of a coaching pilot on students and staff (2019)
Journal Article
Green. (2019). Evaluating the impact of a coaching pilot on students and staff. British Journal of Nursing, 1394 - 1398. https://doi.org/10.12968/bjon.2019.28.21.1394

A coaching pilot was developed following the publication of a number of reports that recommended a review into how student nurses are taught in clinical practice. A bespoke version of the Collaborative Learning in Practice (CLiP) model was developed,... Read More about Evaluating the impact of a coaching pilot on students and staff.

Molecular characterization of group A rotavirus from rhesus macaques (Macaca mulatta) at human-wildlife interfaces in Bangladesh (2019)
Journal Article
Islam, A., Rahman, M. Z., Miah, M., Hossain, M. E., Haider, N., Rostal, M. K., …Epstein, J. H. (2020). Molecular characterization of group A rotavirus from rhesus macaques (Macaca mulatta) at human-wildlife interfaces in Bangladesh. Transboundary and Emerging Diseases, 67(2), 956-966. https://doi.org/10.1111/tbed.13431

Group A rotavirus (RVA) is an important cause of diarrhoea in people, especially children, and animals globally. Due to the segmented nature of the RVA genome, animal RVA strains have the potential to adapt to the human host through reassortment with... Read More about Molecular characterization of group A rotavirus from rhesus macaques (Macaca mulatta) at human-wildlife interfaces in Bangladesh.

Individual participant data meta-analysis of intervention studies with time-to-event outcomes: A review of the methodology and an applied example. (2019)
Journal Article
(2019). Individual participant data meta-analysis of intervention studies with time-to-event outcomes: A review of the methodology and an applied example. Research Synthesis Methods, https://doi.org/10.1002/jrsm.1384

Many randomized trials evaluate an intervention effect on time-to-event outcomes. Individual participant data (IPD) from such trials can be obtained and combined in a so-called IPD meta-analysis (IPD-MA), to summarize the overall intervention effect.... Read More about Individual participant data meta-analysis of intervention studies with time-to-event outcomes: A review of the methodology and an applied example..

Reasons why osteoarthritis predicts mortality: path analysis within a Cox proportional hazards model (2019)
Journal Article
Wilkie, R., Singh Parmar, S., Blagojevic-Bucknall, M., Smith, D., Thomas, M. J., Seale, B. J., …Peat, G. (2019). Reasons why osteoarthritis predicts mortality: path analysis within a Cox proportional hazards model. RMD Open, 5(2), Article e001048. https://doi.org/10.1136/rmdopen-2019-001048

Objectives: To identify potentially modifiable factors that mediate the association between symptomatic osteoarthritis (OA) and premature mortality. Methods: A population-based prospective cohort study; primary care medical record data were linked to... Read More about Reasons why osteoarthritis predicts mortality: path analysis within a Cox proportional hazards model.

Virtual patient technology to teach pharmacists NOAC counselling – Questionnaire development, validation and pilot (2019)
Journal Article
Richardson, C., White, S., & Chapman, S. (2019). Virtual patient technology to teach pharmacists NOAC counselling – Questionnaire development, validation and pilot. BMJ Simulation and Technology Enhanced Learning, A77 - A77. https://doi.org/10.1136/bmjstel-2019-aspihconf.142

Abstract
Background Keele University has developed a virtual patient (VP) educational tool to teach pharmacists how to conduct non-vitamin K oral anticoagulant (NOAC) counselling. The VP’s use will be evaluated, but in order to do so, a validated da... Read More about Virtual patient technology to teach pharmacists NOAC counselling – Questionnaire development, validation and pilot.

Use of invasive strategies in the management of non-ST elevation acute myocardial infarction and clinical outcomes (2019)
Thesis
Rashid, M. (2019). Use of invasive strategies in the management of non-ST elevation acute myocardial infarction and clinical outcomes. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/414984

Non-elevation acute myocardial infarction (NSTEMI) is one of the commonest phenotype of acute coronary syndrome (ACS) and associated with significant morbidity and mortality at the short and long term. An invasive strategy in the form of coronary ang... Read More about Use of invasive strategies in the management of non-ST elevation acute myocardial infarction and clinical outcomes.