Applying quantitative bias analysis to estimate the plausible effects of selection bias in a cluster randomised controlled trial: secondary analysis of the Primary care Osteoarthritis Screening Trial (POST). (2017)
Journal Article
Barnett, L., Mallen, C., Lewis, A., & Peat, G. (2017). Applying quantitative bias analysis to estimate the plausible effects of selection bias in a cluster randomised controlled trial: secondary analysis of the Primary care Osteoarthritis Screening Trial (POST). Trials, 18, 585 - ?. https://doi.org/10.1186/s13063-017-2329-1

BACKGROUND: Selection bias is a concern when designing cluster randomised controlled trials (c-RCT). Despite addressing potential issues at the design stage, bias cannot always be eradicated from a trial design. The application of bias analysis prese... Read More about Applying quantitative bias analysis to estimate the plausible effects of selection bias in a cluster randomised controlled trial: secondary analysis of the Primary care Osteoarthritis Screening Trial (POST)..

Prognosis of sciatica and back-related leg pain in primary care: the ATLAS cohort (2017)
Journal Article
Konstantinou, K., Dunn, K., Ogollah, R., Lewis, M., Van Der Windt, D., Hay, E., & Study Team, A. (2017). Prognosis of sciatica and back-related leg pain in primary care: the ATLAS cohort. Spine Journal, 1030-1040. https://doi.org/10.1016/j.spinee.2017.10.071

Background Context
Evidence is lacking on the prognosis and prognostic factors of back-related leg pain and sciatica in patients seeing their primary care physicians. This evidence could guide timely appropriate treatment and referral decisions.... Read More about Prognosis of sciatica and back-related leg pain in primary care: the ATLAS cohort.

The clinical and cost-effectiveness of stratified care for patients with sciatica: the SCOPiC randomised controlled trial protocol (ISRCTN75449581). (2017)
Journal Article
Foster, N. E., Konstantinou, K., Lewis, M., Ogollah, R., Dunn, K. M., van der Windt, D., …Hay, E. M. (2017). The clinical and cost-effectiveness of stratified care for patients with sciatica: the SCOPiC randomised controlled trial protocol (ISRCTN75449581). BMC Musculoskeletal Disorders, 18, Article 172. https://doi.org/10.1186/s12891-017-1513-5

BACKGROUND: Sciatica has a substantial impact on patients, and is associated with high healthcare and societal costs. Although there is variation in the clinical management of sciatica, the current model of care usually involves an initial period of... Read More about The clinical and cost-effectiveness of stratified care for patients with sciatica: the SCOPiC randomised controlled trial protocol (ISRCTN75449581)..

The Estimation and Inclusion of Presenteeism Costs in Applied Economic Evaluation: A Systematic Review. (2017)
Journal Article
Lewis. (2017). The Estimation and Inclusion of Presenteeism Costs in Applied Economic Evaluation: A Systematic Review. Value in Health, 496 - 506. https://doi.org/10.1016/j.jval.2016.12.006

OBJECTIVE: Given the significant costs of reduced productivity (presenteeism) in comparison to absenteeism, and overall societal costs, presenteeism has a potentially important role to play in economic evaluations. However, these costs are often excl... Read More about The Estimation and Inclusion of Presenteeism Costs in Applied Economic Evaluation: A Systematic Review..

Evaluating acupuncture and standard care for pregnant women and back pain: the EASE back pilot randomised controlled trial ((ISRCTN49955124) (2016)
Journal Article
Bishop, A., Ogollah, R., Bartlam, B., Barlas, P., Holden, M. A., Ismail, K. M., …Foster, N. E. (2016). Evaluating acupuncture and standard care for pregnant women and back pain: the EASE back pilot randomised controlled trial ((ISRCTN49955124). Pilot and Feasibility Studies, 2, Article 72. https://doi.org/10.1186/s40814-016-0107-6

Background
Low back pain (LBP) and pelvic girdle pain (PGP) during pregnancy are common and often accepted as a ‘normal’ part of pregnancy. Many women receive little in the way of treatment, and yet pain interferes with sleep, daily activities and w... Read More about Evaluating acupuncture and standard care for pregnant women and back pain: the EASE back pilot randomised controlled trial ((ISRCTN49955124).

Evaluating Acupuncture and Standard carE for pregnant women with Back pain (EASE Back): a feasibility study and pilot randomised trial. (2016)
Journal Article
Foster, N. E., Bishop, A., Bartlam, B., Ogollah, R., Barlas, P., Holden, M., …Young, J. (2016). Evaluating Acupuncture and Standard carE for pregnant women with Back pain (EASE Back): a feasibility study and pilot randomised trial. Health Technology Assessment, 20(33), 1 - 236. https://doi.org/10.3310/hta20330

BACKGROUND: Many pregnant women experience low back pain. Acupuncture appears to be a safe, promising intervention but evidence is needed about its clinical effectiveness and cost-effectiveness. OBJECTIVES: To assess the feasibility of a future large... Read More about Evaluating Acupuncture and Standard carE for pregnant women with Back pain (EASE Back): a feasibility study and pilot randomised trial..

Reliability among clinicians diagnosing low back-related leg pain. (2015)
Journal Article
Stynes, S., Konstantinou, K., Dunn, K., Lewis, M., & Hay, E. (2015). Reliability among clinicians diagnosing low back-related leg pain. European Spine Journal, 25, 2734–2740. https://doi.org/10.1007/s00586-015-4359-2

PURPOSE: To investigate agreement and reliability among clinicians when diagnosing low back-related leg pain (LBLP) in primary care consulters. METHODS: Thirty-six patients were assessed by one of six physiotherapists and diagnosed as having either l... Read More about Reliability among clinicians diagnosing low back-related leg pain..

An empirical evaluation of the impact of missing data on treatment effect (2015)
Presentation / Conference
Royes, J., Sim, J., Ogollah, R., & Lewis, M. (2015, November). An empirical evaluation of the impact of missing data on treatment effect. Poster presented at 3rd International Clinical Trials Methodology Conference, Glasgow, UK

Objectives
Missing data represent a potential source of bias in randomized clinical trials (RCTs). A simple approach that makes use of the responses subsequently obtained via reminder is proposed to assess the validity of the inferences from a missi... Read More about An empirical evaluation of the impact of missing data on treatment effect.

Stratified care for patients with sciatica and suspected sciatica in primary care: the scopic trial protocol (scopic-sciatica outcomes in primary care) (2015)
Presentation / Conference
Foster, N., Konstantinou, K., Beardmore, R., Dunn, K., Lewis, M., Bartlam, B., …Hay, E. (2015, November). Stratified care for patients with sciatica and suspected sciatica in primary care: the scopic trial protocol (scopic-sciatica outcomes in primary care). Poster presented at 3rd International Clinical Trials Methodology Conference, Glasgow

An Economic Evaluation of TENS in Addition to Usual Primary Care Management for the Treatment of Tennis Elbow: Results from the TATE Randomized Controlled Trial (2015)
Journal Article
Lewis, M., Chesterton, L., Sim, J., Hay, E., Mallen, C., & Van Der Windt, D. (2015). An Economic Evaluation of TENS in Addition to Usual Primary Care Management for the Treatment of Tennis Elbow: Results from the TATE Randomized Controlled Trial. PloS one, https://doi.org/10.1371/journal.pone.0135460

Background
The TATE trial was a multicentre pragmatic randomized controlled trial of supplementing primary care management (PCM)–consisting of a GP consultation followed by information and advice on exercises–with transcutaneous electrical nerve sti... Read More about An Economic Evaluation of TENS in Addition to Usual Primary Care Management for the Treatment of Tennis Elbow: Results from the TATE Randomized Controlled Trial.

Transcutaneous electrical nerve stimulation as adjunct to primary care management for tennis elbow: (2014)
Journal Article
Chesterton, L. S., Lewis, A. M., Sim, J., Mallen, C. D., Mason, E. E., Hay, E. M., & van der Windt, D. A. (2014). Transcutaneous electrical nerve stimulation as adjunct to primary care management for tennis elbow:. British Journal of Sports Medicine, 1458 - ?. https://doi.org/10.1136/bjsports-2013-f5160rep

Can transcutaneous electrical nerve stimulation (TENS), as a patient controlled adjunct to primary care management for tennis elbow, provide superior pain relief to primary care management alone.

A systematic review finds variable use of the intention-to-treat principle in musculoskeletal randomized controlled trials with missing data (2014)
Journal Article
Joseph, R., Sim, J., Ogollah, R., & Lewis, M. (2015). A systematic review finds variable use of the intention-to-treat principle in musculoskeletal randomized controlled trials with missing data. Journal of Clinical Epidemiology, 15 - 24. https://doi.org/10.1016/j.jclinepi.2014.09.002

OBJECTIVES: In randomized trials, the primary analysis should be consistent with the intention-to-treat (ITT) principle and should address missing data appropriately to draw valid inferences. This review focuses on current practices relating to the I... Read More about A systematic review finds variable use of the intention-to-treat principle in musculoskeletal randomized controlled trials with missing data.

Agreement of self-reported items and clinically assessed nerve root involvement (or sciatica) in a primary care setting. (2012)
Journal Article
Lewis, & Dunn. (2012). Agreement of self-reported items and clinically assessed nerve root involvement (or sciatica) in a primary care setting. European Spine Journal, 2306 - 2315. https://doi.org/10.1007/s00586-012-2398-5

INTRODUCTION: We analysed baseline measures from an RCT involving adults with low back pain (LBP) with or without referred leg pain, to identify self-report items that best identified clinically determined nerve root involvement (sciatica). METHODS:... Read More about Agreement of self-reported items and clinically assessed nerve root involvement (or sciatica) in a primary care setting..