Skip to main content

Research Repository

Advanced Search

Baseline Risk and Timing of Invasive Strategy for 137,265 Patients Presenting With Non-ST-Segment Elevation Acute Myocardial Infarction: Level of Compliance With International Guidelines (2019)
Journal Article
Mamas. (2019). Baseline Risk and Timing of Invasive Strategy for 137,265 Patients Presenting With Non-ST-Segment Elevation Acute Myocardial Infarction: Level of Compliance With International Guidelines. Journal of the American College of Cardiology, B506 -B506. https://doi.org/10.1016/j.jacc.2019.08.610

Conference poster.

Does prior antithrombotic therapy influence recurrence and bleeding risk in stroke patients with atrial fibrillation or atrial flutter? (2019)
Journal Article
Mamas. (2019). Does prior antithrombotic therapy influence recurrence and bleeding risk in stroke patients with atrial fibrillation or atrial flutter?. European Journal of Preventive Cardiology, 2047487319871709 - 2047487319871709. https://doi.org/10.1177/2047487319871709

Background Whilst antithrombotic therapy is recommended in people with atrial fibrillation, little is known about the survival benefits of antithrombotic treatment in those with both high ischaemic and bleeding risk scores. We aim to describe the dis... Read More about Does prior antithrombotic therapy influence recurrence and bleeding risk in stroke patients with atrial fibrillation or atrial flutter?.

Dietary components and risk of cardiovascular disease and all-cause mortality: A review of evidence from meta-analyses (2019)
Journal Article
Watson, L., Loke, Y., Mallen, C., Mamas, M., Gulati, M., Kwok, C., …Wu, P. (2019). Dietary components and risk of cardiovascular disease and all-cause mortality: A review of evidence from meta-analyses. European Journal of Preventive Cardiology, 26(13), 1415-1429. https://doi.org/10.1177/2047487319843667

Aims
The optimal diet for cardiovascular health is controversial. The aim of this review is to summarize the highest level of evidence and rank the risk associated with each individual component of diet within its food group.

Methods and results... Read More about Dietary components and risk of cardiovascular disease and all-cause mortality: A review of evidence from meta-analyses.

Early Unplanned Readmissions after Admission to Hospital with Heart Failure (2019)
Journal Article
Helliwell, T., Clarson, L., Mallen, C., & Mamas, M. (2019). Early Unplanned Readmissions after Admission to Hospital with Heart Failure. American Journal of Cardiology, 736-745. https://doi.org/10.1016/j.amjcard.2019.05.053

Hospital readmissions remain a continued challenge in the care of patients with heart failure (HF). This study aims to examine the rates, temporal trends, predictors and causes of 30-day unplanned readmissions after admission with HF. Patients hospit... Read More about Early Unplanned Readmissions after Admission to Hospital with Heart Failure.

Combinations of bleeding and ischemic risk and their association with clinical outcomes in acute coronary syndrome. (2019)
Journal Article
Mamas, M., & Rashid, M. (2019). Combinations of bleeding and ischemic risk and their association with clinical outcomes in acute coronary syndrome. International Journal of Cardiology, 7-14. https://doi.org/10.1016/j.ijcard.2019.05.035

Acute coronary syndromes (ACS) are an important cause of morbidity and mortality worldwide. Current guidelines recommend early management with potent antiplatelet agents and an early invasive coronary intervention strategy for both non-ST elevation m... Read More about Combinations of bleeding and ischemic risk and their association with clinical outcomes in acute coronary syndrome..

Readmission and processes of care across weekend and weekday hospitalisation for acute myocardial infarction, heart failure or stroke: an observational study of the National Readmission Database. (2019)
Journal Article
Mamas. (2019). Readmission and processes of care across weekend and weekday hospitalisation for acute myocardial infarction, heart failure or stroke: an observational study of the National Readmission Database. BMJ Open, e029667 - ?. https://doi.org/10.1136/bmjopen-2019-029667

OBJECTIVES: Variation in hospital resource allocations across weekdays and weekends have led to studies of the 'weekend effect' for ST elevation myocardial infarction (STEMI), non-ST elevation myocardial infarction (NSTEMI), heart failure (HF) and st... Read More about Readmission and processes of care across weekend and weekday hospitalisation for acute myocardial infarction, heart failure or stroke: an observational study of the National Readmission Database..

Effect of Concomitant Atrial Fibrillation on In-Hospital Outcomes of Non-ST-Elevation-Acute Coronary Syndrome Related Hospitalizations in the United States (2019)
Journal Article
Mamas, M., & Rashid, M. (2019). Effect of Concomitant Atrial Fibrillation on In-Hospital Outcomes of Non-ST-Elevation-Acute Coronary Syndrome Related Hospitalizations in the United States. American Journal of Cardiology, 465-475. https://doi.org/10.1016/j.amjcard.2019.05.040

Atrial fibrillation (AF) is the most common arrhythmia in patients presenting with acute coronary syndrome (ACS). The present study examined the rates and trends of clinical outcomes and management strategies of non-ST-elevation ACS (NSTE-ACS) relate... Read More about Effect of Concomitant Atrial Fibrillation on In-Hospital Outcomes of Non-ST-Elevation-Acute Coronary Syndrome Related Hospitalizations in the United States.

Pregnancy as a Predictor of Maternal Cardiovascular Disease: The era of CardioObstetrics (2019)
Journal Article
Mamas, & Wu. (2019). Pregnancy as a Predictor of Maternal Cardiovascular Disease: The era of CardioObstetrics. Journal of Women's Health, 1037-1050. https://doi.org/10.1089/jwh.2018.7480

Globally, cardiovascular disease is the most common cause of mortality in women accounting for 1 in 3 deaths. There remains an under recognition of cardiovascular disease as well as a lack of awareness of risk in women. Promotion of cardiovascular di... Read More about Pregnancy as a Predictor of Maternal Cardiovascular Disease: The era of CardioObstetrics.

Percutaneous coronary intervention and in-hospital outcomes in patients with leukemia: a nationwide analysis (2019)
Journal Article
Potts, J., Mohamed, M., Lopez-Mattei, J., Iliescu, C., Konopleva, M., Mamas, M., …Bagur, R. (2019). Percutaneous coronary intervention and in-hospital outcomes in patients with leukemia: a nationwide analysis. Catheterization and Cardiovascular Interventions, https://doi.org/10.1002/ccd.28432

Objectives: To examine the association between current leukemia diagnosis and in-hospital clinical outcomes in patients undergoing percutaneous coronary intervention (PCI) in the US.

Background: Leukemia is most common hematological malignancy and... Read More about Percutaneous coronary intervention and in-hospital outcomes in patients with leukemia: a nationwide analysis.

Same day discharge after elective percutaneous coronary intervention: insights from the British Cardiovascular Intervention Society (2019)
Journal Article
Taxiarchi, P., Kontopantelis, E., Martin, G. P., Kinnaird, T., Curzen, N., Banning, A. P., …Mamas, M. A. (2019). Same day discharge after elective percutaneous coronary intervention: insights from the British Cardiovascular Intervention Society. JACC. Cardiovascular interventions, 1479-1494. https://doi.org/10.1016/j.jcin.2019.03.030

Objectives
We aimed to evaluate national temporal trends of same day discharge (SDD) and compare clinical outcomes to patients admitted for overnight stay (ON) undergoing elective PCI for stable angina.

Background
ON observation has been the st... Read More about Same day discharge after elective percutaneous coronary intervention: insights from the British Cardiovascular Intervention Society.

Prevalence, outcomes and costs according to patient frailty status for 2.9 million cardiac electronic device implantations in the United States (2019)
Journal Article
Mamas, M., & Rashid, M. (2019). Prevalence, outcomes and costs according to patient frailty status for 2.9 million cardiac electronic device implantations in the United States. Canadian Journal of Cardiology, 1465-1474. https://doi.org/10.1016/j.cjca.2019.07.632

Background: Little is known about the impact of frailty on length of stay (LOS), cost and inhospital procedural outcomes of cardiac implantable electronic device (CIED) implantation procedures.

Methods: All de novo CIED implantations recorded in t... Read More about Prevalence, outcomes and costs according to patient frailty status for 2.9 million cardiac electronic device implantations in the United States.

Do ß-adrenoreceptor blocking drugs associate with reduced risk of symptomatic osteoarthritis and total joint replacement in the general population? A primary care-based, prospective cohort study using the Clinical Practice Research Datalink. (2019)
Journal Article
Mallen, & Mamas. (2019). Do ß-adrenoreceptor blocking drugs associate with reduced risk of symptomatic osteoarthritis and total joint replacement in the general population? A primary care-based, prospective cohort study using the Clinical Practice Research Datalink. BMJ Open, e032050 - ?. https://doi.org/10.1136/bmjopen-2019-032050

INTRODUCTION: To investigate if ß-adrenoreceptor blocking drug (ß-blocker) prescription reduces the risk of knee or hip osteoarthritis, total joint replacement and analgesic prescription. SETTING: Primary care. METHODS AND ANALYSIS: This is a cohort... Read More about Do ß-adrenoreceptor blocking drugs associate with reduced risk of symptomatic osteoarthritis and total joint replacement in the general population? A primary care-based, prospective cohort study using the Clinical Practice Research Datalink..

Weekend effect in acute coronary syndrome: A meta-analysis of observational studies. (2019)
Journal Article
Mamas. (2019). Weekend effect in acute coronary syndrome: A meta-analysis of observational studies. European Heart Journal: Acute Cardiovascular Care, 432-442. https://doi.org/10.1177/2048872618762634

BACKGROUND:
The effect of a weekend compared with a weekday hospital admission on patient outcomes after an acute coronary syndrome is unclear. This study aims to determine whether collectively there is a weekend effect in acute coronary syndrome.... Read More about Weekend effect in acute coronary syndrome: A meta-analysis of observational studies..

20-year trends in cause-specific heart failure outcomes by sex, socioeconomic status, and place of diagnosis: a population-based study (2019)
Journal Article
Mamas. (2019). 20-year trends in cause-specific heart failure outcomes by sex, socioeconomic status, and place of diagnosis: a population-based study. The Lancet Public Health, 406-420. https://doi.org/10.1016/S2468-2667%2819%2930108-2

Background:
Heart failure (HF) is a global pandemic but contemporary trends in cause-specific outcomes among different population groups are unknown.

Methods:
In a retrospective cohort of incident HF patients between 1998 and 2017 (N=88,416,... Read More about 20-year trends in cause-specific heart failure outcomes by sex, socioeconomic status, and place of diagnosis: a population-based study.

The comorbidity burden of type 2 diabetes mellitus: patterns, clusters and predictions from a large English primary care cohort. (2019)
Journal Article
Nowakowska, M., Zghebi, S. S., Ashcroft, D. M., Buchan, I., Chew-Graham, C., Holt, T., …Kontopantelis, E. (2019). The comorbidity burden of type 2 diabetes mellitus: patterns, clusters and predictions from a large English primary care cohort. BMC Medicine, https://doi.org/10.1186/s12916-019-1373-y

BACKGROUND: The presence of additional chronic conditions has a significant impact on the treatment and management of type 2 diabetes (T2DM). Little is known about the patterns of comorbidities in this population. The aims of this study are to quanti... Read More about The comorbidity burden of type 2 diabetes mellitus: patterns, clusters and predictions from a large English primary care cohort..

Acute Myocardial Infarction in Severe Mental Illness: prevalence, clinical outcomes and process of care in United States hospitalizations. (2019)
Journal Article
Farooq, S., Chew-Graham, C., Mamas, M., & Rashid, M. (2019). Acute Myocardial Infarction in Severe Mental Illness: prevalence, clinical outcomes and process of care in United States hospitalizations. Canadian Journal of Cardiology, 821-830. https://doi.org/10.1016/j.cjca.2019.04.021

Patients with severe mental illness (SMI) are a high-risk group for cardiovascular disease. The present study examined the prevalence and outcomes of SMI patients in a national AMI cohort. SMI has doubled in prevalence amongst AMI patients, mainly du... Read More about Acute Myocardial Infarction in Severe Mental Illness: prevalence, clinical outcomes and process of care in United States hospitalizations..

Characteristics and outcome of acute heart failure patients according to the severity of peripheral oedema (2019)
Journal Article
Mamas, M., Rashid, M., & Nolan, J. (2019). Characteristics and outcome of acute heart failure patients according to the severity of peripheral oedema. International Journal of Cardiology, 40 -46. https://doi.org/10.1016/j.ijcard.2019.03.020

BACKGROUND: Most trials of patients hospitalized for heart failure focus on breathlessness (alveolar pulmonary oedema) but worsening peripheral oedema is also an important presentation. We investigated the relationship between the severity of periphe... Read More about Characteristics and outcome of acute heart failure patients according to the severity of peripheral oedema.

Cardiovascular risk and risk factor management in type 2 diabetes: a population-based cohort study assessing sex disparities (2019)
Journal Article
Mamas. (2019). Cardiovascular risk and risk factor management in type 2 diabetes: a population-based cohort study assessing sex disparities. Circulation, 2742-2753. https://doi.org/10.1161/CIRCULATIONAHA.118.039100

Background:
With recent changes in UK clinical practice for diabetes care, contemporary estimates of sex disparities in cardiovascular risk and risk factor management are needed.

Methods:
In this retrospective cohort study, using the Clinical P... Read More about Cardiovascular risk and risk factor management in type 2 diabetes: a population-based cohort study assessing sex disparities.