Optimal cut-off threshold in pulse pressure predicting cardiovascular death among newly diagnosed end-stage renal disease patients: A prospective cohort study. (2019)
Journal Article
Yu. (2019). Optimal cut-off threshold in pulse pressure predicting cardiovascular death among newly diagnosed end-stage renal disease patients: A prospective cohort study. Medicine, 98(27), Article e16340. https://doi.org/10.1097/MD.0000000000016340

Cardiovascular disease (CVD) is the leading cause of death in patients with end-stage renal disease (ESRD) treated by dialysis. Pulse pressure (PP) as an independent prognostic factor of cardiovascular risk might be clinically implicated in predictin... Read More about Optimal cut-off threshold in pulse pressure predicting cardiovascular death among newly diagnosed end-stage renal disease patients: A prospective cohort study..

Musculoskeletal pain and exercise: challenging existing paradigms and introducing new: an educational review (2019)
Journal Article
(2019). Musculoskeletal pain and exercise: challenging existing paradigms and introducing new: an educational review. British Journal of Sports Medicine, 907-913. https://doi.org/10.1136/bjsports-2017-098983

Traditional pain models that describe tissue pathology as a source of nocioceptive input directly linked with pain expression, have been insufficient for assessing and treating musculoskeletal pain. The need for pain to be avoided or alleviated as mu... Read More about Musculoskeletal pain and exercise: challenging existing paradigms and introducing new: an educational review.

Response to: Losina E. Why past research successes do not translate to clinical reality: gaps in evidence on exercise program efficiency. Osteoarthritis and Cartilage 2019;27:1-2 (2019)
Journal Article
Swaithes, L., Dziedzic, K., Cottrell, E., & Quicke, J. (2019). Response to: Losina E. Why past research successes do not translate to clinical reality: gaps in evidence on exercise program efficiency. Osteoarthritis and Cartilage 2019;27:1-2. Osteoarthritis and Cartilage, e7-e8. https://doi.org/10.1016/j.joca.2019.02.801

Letter to the editor.

Opioids for musculoskeletal pain and their associations with reproductive and sexual function in women: an epidemiological study (2019)
Thesis
Richardson, E. (2019). Opioids for musculoskeletal pain and their associations with reproductive and sexual function in women: an epidemiological study. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/414417

Background
One fifth of primary care attendees report chronic non cancer pain (CNCP) most of which is related to musculoskeletal conditions, 12% of these are prescribed strong opioid analgesics. Evidence suggests long-term opioid use causes hypogona... Read More about Opioids for musculoskeletal pain and their associations with reproductive and sexual function in women: an epidemiological study.

The role of deprivation and quality of care on healthy ageing in older people with musculoskeletal pain: a prospective study (2019)
Thesis
Rhys, G. C. (2019). The role of deprivation and quality of care on healthy ageing in older people with musculoskeletal pain: a prospective study. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/417818

Background: Musculoskeletal pain is common in older adults and is associated with a decrease in the Healthy Ageing Index (HAI) (a validated composite ageing measure). Deprivation measures were not included in the HAI. The literature advocates includi... Read More about The role of deprivation and quality of care on healthy ageing in older people with musculoskeletal pain: a prospective study.

Depression predicts emergency care use in people with chronic obstructive pulmonary disease: a large cohort study in primary care. (2019)
Journal Article
Chew-Graham. (2019). Depression predicts emergency care use in people with chronic obstructive pulmonary disease: a large cohort study in primary care. International Journal of Chronic Obstructive Pulmonary Disease, 1343 - 1353. https://doi.org/10.2147/COPD.S179109

Background: Depression is common in people with chronic obstructive pulmonary disease (COPD) and has been associated with a variety of poor outcomes. A large proportion of health care costs in the UK are spent on emergency care. This study examined t... Read More about Depression predicts emergency care use in people with chronic obstructive pulmonary disease: a large cohort study in primary care..

TARGETS FOR REDUCING PREMATURE MORTALITY IN OLDER ADULTS WITH OSTEOARTHRITIS: RESULTS FROM A NOVEL PATH ANALYSIS WITHIN A COX PROPORTIONAL HAZARDS MODEL (2019)
Journal Article
Wilkie, R., Parmar, S., & Bucknall, M. (2019). TARGETS FOR REDUCING PREMATURE MORTALITY IN OLDER ADULTS WITH OSTEOARTHRITIS: RESULTS FROM A NOVEL PATH ANALYSIS WITHIN A COX PROPORTIONAL HAZARDS MODEL. Annals of the Rheumatic Diseases, 78-S2, 152 - 153. https://doi.org/10.1136/annrheumdis-2019-eular.5862

Objectives The objectives of this study were to identify potential mechanisms of the impact of osteoarthritis on mortality and examine the role of modifiable targets (anxiety, depression, insomnia and walking frequency) for health professionals in rh... Read More about TARGETS FOR REDUCING PREMATURE MORTALITY IN OLDER ADULTS WITH OSTEOARTHRITIS: RESULTS FROM A NOVEL PATH ANALYSIS WITHIN A COX PROPORTIONAL HAZARDS MODEL.

Routine x-rays for suspected Frozen Shoulder offer little over diagnosis based on history and clinical examination alone (2019)
Journal Article
(2019). Routine x-rays for suspected Frozen Shoulder offer little over diagnosis based on history and clinical examination alone. Musculoskeletal Care, 288-292. https://doi.org/10.1002/msc.1396

Background
Frozen shoulder is a common condition and current guidelines state that it is a diagnosis of exclusion. Along with a history and clinical examination, routine x-ray is mandated to rule out any masquerading pathology such as fracture, disl... Read More about Routine x-rays for suspected Frozen Shoulder offer little over diagnosis based on history and clinical examination alone.

Gender-specific risk factors for gout: a systematic review of cohort studies (2019)
Journal Article
Evans, P. L., Prior, J. A., Belcher, J., Hay, C. A., Mallen, C. D., & Roddy, E. (2019). Gender-specific risk factors for gout: a systematic review of cohort studies. Advances in Rheumatology, 59, Article 24. https://doi.org/10.1186/s42358-019-0067-7

BACKGROUND:
Though gout is more prevalent in men than women, it remains unclear whether gender influences risk factors for incident gout. We aimed to systematically review all cohort studies examining risk factors for the development of gout by gend... Read More about Gender-specific risk factors for gout: a systematic review of cohort studies.

Incidence of infections associated with oral glucocorticoid dose in people diagnosed with polymyalgia rheumatica or giant cell arteritis: a cohort study in England (2019)
Journal Article
Mallen. (2019). Incidence of infections associated with oral glucocorticoid dose in people diagnosed with polymyalgia rheumatica or giant cell arteritis: a cohort study in England. Canadian Medical Association Journal, E680 - E688. https://doi.org/10.1503/cmaj.190178

BACKGROUND: Most patients with polymyalgia rheumatica or giant cell arteritis are treated with glucocorticoid therapy in primary care. We estimated dose-response risks of infection for this population in England.

METHODS: We conducted a retrospect... Read More about Incidence of infections associated with oral glucocorticoid dose in people diagnosed with polymyalgia rheumatica or giant cell arteritis: a cohort study in England.

Factors associated with costs and health outcomes in patients with Back and leg pain in primary care: a prospective cohort analysis (2019)
Journal Article
Kigozi, J., Konstantinou, K., Ogollah, R., Dunn, K., Lewis, M., & Jowett, S. (2019). Factors associated with costs and health outcomes in patients with Back and leg pain in primary care: a prospective cohort analysis. BMC Health Services Research, https://doi.org/10.1186/s12913-019-4257-0

Background
There is limited research on the economic burden of low back-related leg pain, including sciatica. The aim of this study was to describe healthcare resource utilisation and factors associated with cost and health outcomes in primary care... Read More about Factors associated with costs and health outcomes in patients with Back and leg pain in primary care: a prospective cohort analysis.

Characteristics and outcome of acute heart failure patients according to the severity of peripheral oedema (2019)
Journal Article
Mamas, M., Rashid, M., & Nolan, J. (2019). Characteristics and outcome of acute heart failure patients according to the severity of peripheral oedema. International Journal of Cardiology, 40 -46. https://doi.org/10.1016/j.ijcard.2019.03.020

BACKGROUND: Most trials of patients hospitalized for heart failure focus on breathlessness (alveolar pulmonary oedema) but worsening peripheral oedema is also an important presentation. We investigated the relationship between the severity of periphe... Read More about Characteristics and outcome of acute heart failure patients according to the severity of peripheral oedema.

Cardiovascular risk and risk factor management in type 2 diabetes: a population-based cohort study assessing sex disparities (2019)
Journal Article
Mamas. (2019). Cardiovascular risk and risk factor management in type 2 diabetes: a population-based cohort study assessing sex disparities. Circulation, 2742-2753. https://doi.org/10.1161/CIRCULATIONAHA.118.039100

Background:
With recent changes in UK clinical practice for diabetes care, contemporary estimates of sex disparities in cardiovascular risk and risk factor management are needed.

Methods:
In this retrospective cohort study, using the Clinical P... Read More about Cardiovascular risk and risk factor management in type 2 diabetes: a population-based cohort study assessing sex disparities.

Percutaneous Coronary Intervention in Cancer Patients: A Report of the Prevalence and Outcomes in the United States (2019)
Journal Article
Potts, J., Lopez Mattei, J., Martinez, S., Fischman, D., Mamas, M., Iliescu, C., …Rashid, M. (2019). Percutaneous Coronary Intervention in Cancer Patients: A Report of the Prevalence and Outcomes in the United States. European Heart Journal, 1790-+. https://doi.org/10.1093/eurheartj/ehy769

This study aims to examine the temporal trends and outcomes in patients who undergo percutaneous coronary intervention (PCI) with a previous or current diagnosis of cancer, according to cancer type and the presence of metastases.

Methods and resul... Read More about Percutaneous Coronary Intervention in Cancer Patients: A Report of the Prevalence and Outcomes in the United States.

Protocol for a multi-centre pilot and feasibility randomised controlled trial with a nested qualitative study: rehabilitation following rotator cuff repair (the RaCeR study) (2019)
Journal Article
Littlewood, C., Bateman, M., Cooke, K., Hennnings, S., Cookson, T., Bromley, K., …Foster, N. E. (2019). Protocol for a multi-centre pilot and feasibility randomised controlled trial with a nested qualitative study: rehabilitation following rotator cuff repair (the RaCeR study). Trials, 20, Article 328. https://doi.org/10.1186/s13063-019-3407-3

Background
Shoulder pain is a highly prevalent complaint and disorders of the rotator cuff, including tears, are thought to be the most common cause. The number of operations repair the torn rotator cuff has risen significantly in recent years. Whil... Read More about Protocol for a multi-centre pilot and feasibility randomised controlled trial with a nested qualitative study: rehabilitation following rotator cuff repair (the RaCeR study).

2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout. (2019)
Journal Article
Richette, P., Doherty, M., Pascual, E., Barskova, V., Becce, F., Castaneda, J., …Bardin, T. (2019). 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout. Annals of the Rheumatic Diseases, 79(1), 31 - 38. https://doi.org/10.1136/annrheumdis-2019-215315

Although gout is the most common inflammatory arthritis, it is still frequently misdiagnosed. New data on imaging and clinical diagnosis have become available since the first EULAR recommendations for the diagnosis of gout in 2006. This prompted a sy... Read More about 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout..

Venous thromboembolism in patients with gout and the impact of hospital admission, disease duration and urate-lowering therapy. (2019)
Journal Article
Mallen, C., Roddy, E., Clarson, L., & Muller, S. (2019). Venous thromboembolism in patients with gout and the impact of hospital admission, disease duration and urate-lowering therapy. Canadian Medical Association Journal, 191(22), E597 - E603. https://doi.org/10.1503/cmaj.180717

BACKGROUND: Systemic inflammatory diseases have been associated with increased risk of venous thromboembolism. We aimed to quantify the risk of venous thromboembolism in patients with gout, the most common inflammatory arthritis, and to assess how di... Read More about Venous thromboembolism in patients with gout and the impact of hospital admission, disease duration and urate-lowering therapy..

Sharing information about diagnosis and outcome of firstepisode psychosis in patients presenting to early intervention services (2019)
Journal Article
Farooq. (2019). Sharing information about diagnosis and outcome of firstepisode psychosis in patients presenting to early intervention services. Early Intervention in Psychiatry, 657-666. https://doi.org/10.1111/eip.12670

Aim
First-episode psychosis (FEP) can be a serious and debilitating disease, but there is limited literature on how to inform patients and carers about its diagnosis and outcome. We aimed to examine the attitudes, practices and views of clinicians w... Read More about Sharing information about diagnosis and outcome of firstepisode psychosis in patients presenting to early intervention services.

The reliability and clinical utility of ICD-11 schizoaffective disorder: A field trial. (2019)
Journal Article
Farooq. (2019). The reliability and clinical utility of ICD-11 schizoaffective disorder: A field trial. Schizophrenia Research, 235-241. https://doi.org/10.1016/j.schres.2019.02.011

A major goal for the revision of the International Classification of Diseases and Related Health Problems, Tenth Edition (ICD-10) is to increase the clinical utility of the diagnostic system. Schizoaffective disorder has a history of poor diagnostic... Read More about The reliability and clinical utility of ICD-11 schizoaffective disorder: A field trial..

Matching treatment options for risk sub-groups in musculoskeletal pain: a consensus groups study (2019)
Journal Article
Protheroe, J., Saunders, B., Bartlam, B., Dunn, K., Cooper, V., Campbell, P., …Foster, N. (2019). Matching treatment options for risk sub-groups in musculoskeletal pain: a consensus groups study. BMC Musculoskeletal Disorders, https://doi.org/10.1186/s12891-019-2587-z

Background
Musculoskeletal (MSK) pain represents a considerable worldwide healthcare burden. This study aimed to gain consensus from practitioners who work with MSK pain patients, on the most appropriate primary care treatment options for subgroups... Read More about Matching treatment options for risk sub-groups in musculoskeletal pain: a consensus groups study.