Better Outcomes for Older people with Spinal Trouble (BOOST) Trial: a randomised controlled trial of a combined physical and psychological intervention for older adults with neurogenic claudication, a protocol. (2018)
Journal Article
Mallen. (2018). Better Outcomes for Older people with Spinal Trouble (BOOST) Trial: a randomised controlled trial of a combined physical and psychological intervention for older adults with neurogenic claudication, a protocol. BMJ Open, e022205 - ?. https://doi.org/10.1136/bmjopen-2018-022205

INTRODUCTION: Neurogenic claudication due to spinal stenosis is common in older adults. The effectiveness of conservative interventions is not known. The aim of the study is to estimate the clinical and cost-effectiveness of a physiotherapist-deliver... Read More about Better Outcomes for Older people with Spinal Trouble (BOOST) Trial: a randomised controlled trial of a combined physical and psychological intervention for older adults with neurogenic claudication, a protocol..

The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial. (2018)
Journal Article
Chesterton, L. S., Blagojevic-Bucknall, M., Burton, C., Dziedzic, K. S., Davenport, G., Jowett, S. M., …Roddy, E. (2018). The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial. The Lancet, 392(10156), 1423 - 1433. https://doi.org/10.1016/s0140-6736%2818%2931572-1

Background
To our knowledge, the comparative effectiveness of commonly used conservative treatments for carpal tunnel syndrome has not been evaluated previously in primary care. We aimed to compare the clinical and cost-effectiveness of night splint... Read More about The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial..

Identification and Evaluation of Self-Report Physical Activity Instruments in Adults With Osteoarthritis: A Systematic Review (2018)
Journal Article
Dziedzic, K., Holden, M., & Healey, E. L. (2019). Identification and Evaluation of Self-Report Physical Activity Instruments in Adults With Osteoarthritis: A Systematic Review. Arthritis Care and Research, 71(2), 237-251. https://doi.org/10.1002/acr.23787

OBJECTIVE
To identify and evaluate the measurement properties of self-report physical activity (PA) instruments suitable for those with osteoarthritis (OA).

METHODS
A comprehensive two-stage systematic review using multiple electronic databases... Read More about Identification and Evaluation of Self-Report Physical Activity Instruments in Adults With Osteoarthritis: A Systematic Review.

Procedural success and outcomes with increasing use of enabling strategies for chronic total occlusion intervention: an analysis of 28,050 cases from the British Cardiovascular Intervention Society database (2018)
Journal Article
Kinnaird, T., Cockburn, J., Sirker, A., Ludman, P., de Belder, M., Smith, E., …Hildick-Smith, D. (2018). Procedural success and outcomes with increasing use of enabling strategies for chronic total occlusion intervention: an analysis of 28,050 cases from the British Cardiovascular Intervention Society database. Circulation: Cardiovascular Interventions, https://doi.org/10.1161/CIRCINTERVENTIONS.118.006436

BACKGROUND
Enabling strategies (ESs) are increasingly used during percutaneous coronary intervention for chronic total occlusive disease (CTO-PCI), enhancing procedural success. Using the British Cardiovascular Society dataset, we examined changes i... Read More about Procedural success and outcomes with increasing use of enabling strategies for chronic total occlusion intervention: an analysis of 28,050 cases from the British Cardiovascular Intervention Society database.

The role of diet in serum urate concentration. (2018)
Journal Article
Roddy, & Watson. (2018). The role of diet in serum urate concentration. BMJ, k4140 - ?. https://doi.org/10.1136/bmj.k4140

Editorial.

Hand osteoarthritis: clinical phenotypes, molecular mechanisms and disease management (2018)
Journal Article
Marshall, M., Watt, F. E., Vincent, T. L., & Dziedzic, K. (2018). Hand osteoarthritis: clinical phenotypes, molecular mechanisms and disease management. Nature Reviews Rheumatology, 14, 641-656. https://doi.org/10.1038/s41584-018-0095-4

Osteoarthritis (OA) is a highly prevalent condition and the hand is the most commonly affected site. Patients with hand OA frequently report symptoms of pain, functional limitations, and frustration in undertaking everyday activities. The condition p... Read More about Hand osteoarthritis: clinical phenotypes, molecular mechanisms and disease management.

Vitamin B3 and Neurodevelopment in Parkinson's Disease (2018)
Presentation / Conference
(2018, October). Vitamin B3 and Neurodevelopment in Parkinson's Disease. Presented at 2018 International Congress, Hong Kong

Vitamin B3 and Neurodevelopment in Parkinson’s Disease
A. Williams, S. Griffin, R. Fricker (Birmingham, United Kingdom)

Meeting: 2018 International Congress

ABSTRACT NUMBER: 592

Keywords: Cell replacement therapy, Dopaminergic neurons

Se... Read More about Vitamin B3 and Neurodevelopment in Parkinson's Disease.

The frequency of testing for glycated haemoglobin, HbA1c, is linked to the probability of achieving target levels in patients with suboptimally controlled diabetes mellitus. (2018)
Journal Article
Duff, C. J., Solis-Trapala, I., Driskell, O. J., Holland, D., Wright, H., Waldron, J. L., …Fryer, A. A. (2018). The frequency of testing for glycated haemoglobin, HbA1c, is linked to the probability of achieving target levels in patients with suboptimally controlled diabetes mellitus. Clinical Chemistry and Laboratory Medicine, https://doi.org/10.1515/cclm-2018-0503

Introduction:
We previously showed, in patients with diabetes, that >50% of monitoring tests for glycated hemoglobin (HbA1c) are outside recommended intervals and that this is linked to diabetes control. Here, we examined the impact of tests/year on... Read More about The frequency of testing for glycated haemoglobin, HbA1c, is linked to the probability of achieving target levels in patients with suboptimally controlled diabetes mellitus..

Biographical suspension and liminality of Self in accounts of severe sciatica (2018)
Journal Article
Saunders, B., Bartlam, B., Artus, M., & Konstantinou, K. (2018). Biographical suspension and liminality of Self in accounts of severe sciatica. Social Science and Medicine, 218, 28 -36. https://doi.org/10.1016/j.socscimed.2018.10.001

Sciatica is a common form of low back pain (LBP) that has been identified as distinct both in terms of the persistence and severity of symptoms. Little research has explored individual experiences of sciatica, and none focuses on individuals with the... Read More about Biographical suspension and liminality of Self in accounts of severe sciatica.

Predictors and temporal trend of flu vaccination in auto-immune rheumatic diseases in the UK: a nationwide prospective cohort study (2018)
Journal Article
Mallen. (2018). Predictors and temporal trend of flu vaccination in auto-immune rheumatic diseases in the UK: a nationwide prospective cohort study. Rheumatology, 1726-1734. https://doi.org/10.1093/rheumatology/key156

Objectives
To examine temporal trend in uptake of seasonal influenza vaccine (SIV) in the UK and explore disease and demographic factors associated with vaccination.

Methods
From the Clinical Practice Research Datalink, 32 751 people with auto-i... Read More about Predictors and temporal trend of flu vaccination in auto-immune rheumatic diseases in the UK: a nationwide prospective cohort study.

Derivation and external validation of risk algorithms for cerebrovascular (re)hospitalisation in patients with type 2 diabetes: two cohorts study. (2018)
Journal Article
Yu. (2018). Derivation and external validation of risk algorithms for cerebrovascular (re)hospitalisation in patients with type 2 diabetes: two cohorts study. Diabetes Research and Clinical Practice, 74-81. https://doi.org/10.1016/j.diabres.2018.08.006

Aims
Cerebrovascular disease is one of more typical reasons for hospitalisation and re-hospitalisation in people with type 2 diabetes. We aimed to derive and externally validate two risk prediction algorithms for cerebrovascular hospitalisation and... Read More about Derivation and external validation of risk algorithms for cerebrovascular (re)hospitalisation in patients with type 2 diabetes: two cohorts study..

Association of Same-Day Discharge After Elective Percutaneous Coronary Intervention in the United States With Costs and Outcomes (2018)
Journal Article
Mamas. (2018). Association of Same-Day Discharge After Elective Percutaneous Coronary Intervention in the United States With Costs and Outcomes. JAMA Cardiology, https://doi.org/10.1001/jamacardio.2018.3029

Importance
Same-day discharge (SDD) after elective percutaneous coronary intervention (PCI) is associated with lower costs and preferred by patients. However, to our knowledge, contemporary patterns of SDD after elective PCI with respect to the inci... Read More about Association of Same-Day Discharge After Elective Percutaneous Coronary Intervention in the United States With Costs and Outcomes.

Screening of the cervical spine in sub-acromial shoulder pain: a systematic review (2018)
Journal Article
(2018). Screening of the cervical spine in sub-acromial shoulder pain: a systematic review. Shoulder and Elbow,

Background
Sub-acromial shoulder pain (SASP) is a common clinical presentation with much diagnostic uncertainty. Some of this uncertainty relates to the involvement of the cervical spine as a source or contribution to SASP. Currently, there is no ac... Read More about Screening of the cervical spine in sub-acromial shoulder pain: a systematic review.

Chronic kidney disease, worsening renal function and outcomes in a heart failure community setting: A UK national study (2018)
Journal Article
Mamas. (2018). Chronic kidney disease, worsening renal function and outcomes in a heart failure community setting: A UK national study. International Journal of Cardiology, 120 - 127. https://doi.org/10.1016/j.ijcard.2018.04.090

Background Routine heart failure (HF) monitoring and management is in the community but the natural course of worsening renal function (WRF) and its influence on HF prognosis is unknown. We investigated the influence of routinely monitored renal decl... Read More about Chronic kidney disease, worsening renal function and outcomes in a heart failure community setting: A UK national study.

Identifying Asthmatic Children using Tidal Breathing Parameters Measured by Structured Light Plethysmography (SLP) (2018)
Presentation / Conference
Gilchrist. (2018, September). Identifying Asthmatic Children using Tidal Breathing Parameters Measured by Structured Light Plethysmography (SLP). Presented at ERS International Congress 2018, Paris, France

Introduction: We have previously shown that several tidal breathing parameters measured using SLP varied between asthmatic children and healthy (Hmeidi et al., 2017). However, we did not test the classification power of a model which incorporates the... Read More about Identifying Asthmatic Children using Tidal Breathing Parameters Measured by Structured Light Plethysmography (SLP).

Changes in Peri-procedural Bleeding Complications Following Percutaneous Coronary Intervention in The United Kingdom Between 2006-2013 (From the British Cardiovascular Interventional Society) (2018)
Journal Article
Mamas, M., Nolan, J., & Rashid, M. (2018). Changes in Peri-procedural Bleeding Complications Following Percutaneous Coronary Intervention in The United Kingdom Between 2006-2013 (From the British Cardiovascular Interventional Society). American Journal of Cardiology, 952-960. https://doi.org/10.1016/j.amjcard.2018.06.016

Major bleeding is a common complication following percutaneous coronary intervention (PCI), although little is known about how bleeding rates have changed over time and what has driven this. We analyzed all patients undergoing PCI in England and Wale... Read More about Changes in Peri-procedural Bleeding Complications Following Percutaneous Coronary Intervention in The United Kingdom Between 2006-2013 (From the British Cardiovascular Interventional Society).

Item response theory evaluation of the biomedical scale of the Pain Attitudes and Beliefs Scale. (2018)
Journal Article
(2018). Item response theory evaluation of the biomedical scale of the Pain Attitudes and Beliefs Scale. PloS one, e0202539 - ?. https://doi.org/10.1371/journal.pone.0202539

OBJECTIVES: The assessment of health care professionals' attitudes and beliefs towards musculoskeletal pain is essential because they are key determinants of their clinical practice behaviour. The Pain Attitudes and Beliefs Scale (PABS) biomedical sc... Read More about Item response theory evaluation of the biomedical scale of the Pain Attitudes and Beliefs Scale..

Underrecording of osteoarthritis in United Kingdom primary care electronic health record data (2018)
Journal Article
Yu, D., Jordan, K., & Peat, G. (2018). Underrecording of osteoarthritis in United Kingdom primary care electronic health record data. Clinical Epidemiology, 1195-1201. https://doi.org/10.2147/CLEP.S160059

Purpose: Primary care electronic health records are increasingly used to estimate the occurrence of osteoarthritis (OA). We aimed to estimate the extent and trend over time of underrecording of severe OA patients in UK primary care electronic health... Read More about Underrecording of osteoarthritis in United Kingdom primary care electronic health record data.

Mortality after admission for heart failure in the UK compared with Japan. (2018)
Journal Article
(2018). Mortality after admission for heart failure in the UK compared with Japan. Open Heart, e000811 - ?. https://doi.org/10.1136/openhrt-2018-000811

Objective: Mortality amongst patients hospitalised for heart failure (HHF) in Western and Asian countries may differ, but this has not been investigated using individual patient-level data (IPLD). We sought to remedy this through rigorous statistical... Read More about Mortality after admission for heart failure in the UK compared with Japan..

Coexistence of plantar calcaneal spurs and plantar fascial thickening in individuals with plantar heel pain (2018)
Journal Article
Menz, H. B., Thomas, M., Marshall, M., Rathod-Mistry, T., Hall, A., Chesterton, L. S., …Roddy, E. (2019). Coexistence of plantar calcaneal spurs and plantar fascial thickening in individuals with plantar heel pain. Rheumatology, 58(2), 237-245. https://doi.org/10.1093/rheumatology/key266

Objectives
To examine associations between plantar calcaneal spurs, plantar fascia thickening and plantar heel pain (PHP), and to determine whether tenderness on palpation of the heel differentiates between these presentations.

Methods
Adults... Read More about Coexistence of plantar calcaneal spurs and plantar fascial thickening in individuals with plantar heel pain.