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Comparison and reproducibility of standard and high temporal resolution myocardial tissue tagging in patients with severe aortic stenosis (2011)
Journal Article
(2011). Comparison and reproducibility of standard and high temporal resolution myocardial tissue tagging in patients with severe aortic stenosis. Journal of Cardiovascular Magnetic Resonance, P311 - P311. https://doi.org/10.1186/1532-429X-13-S1-P311

Objectives
The aim of this study was to compare and assess the reproducibility of left ventricular (LV) circumferential peak systolic strain (PeakEcc) and strain rate (SR) measurements using standard and high temporal resolution myocardial tissue ta... Read More about Comparison and reproducibility of standard and high temporal resolution myocardial tissue tagging in patients with severe aortic stenosis.

Anterior knee pain in younger adults as a precursor to subsequent patellofemoral osteoarthritis: a systematic review (2010)
Journal Article
(2010). Anterior knee pain in younger adults as a precursor to subsequent patellofemoral osteoarthritis: a systematic review. BMC Musculoskeletal Disorders, 201 -?. https://doi.org/10.1186/1471-2474-11-201

BACKGROUND: Patellofemoral osteoarthritis (PFOA) is a common form of knee OA in middle and older age, but its relation to PF disorders and symptoms earlier in life is unclear. Our aim was to conduct a systematic review to investigate the strength of... Read More about Anterior knee pain in younger adults as a precursor to subsequent patellofemoral osteoarthritis: a systematic review.

The Staffordshire Arthritis, Musculoskeletal, and Back Assessment (SAMBA) Study: a prospective observational study of patient outcome following referral to a primary-secondary care musculoskeletal interface service (2010)
Journal Article
Jordan, Roddy, Zwierska, Hay, & Hider. (2010). The Staffordshire Arthritis, Musculoskeletal, and Back Assessment (SAMBA) Study: a prospective observational study of patient outcome following referral to a primary-secondary care musculoskeletal interface service. BMC Musculoskeletal Disorders, 67 -?. https://doi.org/10.1186/1471-2474-11-67

Background
Recent healthcare policy has shifted the management of musculoskeletal conditions in the UK away from secondary care towards Clinical Assessment and Treatment Services at the primary-secondary care interface. However, little is known abou... Read More about The Staffordshire Arthritis, Musculoskeletal, and Back Assessment (SAMBA) Study: a prospective observational study of patient outcome following referral to a primary-secondary care musculoskeletal interface service.

Addressing patient beliefs and expectations in the consultation (2010)
Journal Article
(2010). Addressing patient beliefs and expectations in the consultation. https://doi.org/10.1016/j.berh.2009.12.013

In this article, we specifically focus on the identification and management of patient beliefs and expectations during consultations with health-care professionals (HCPs). In examination of the nature and purpose of communication during consultations... Read More about Addressing patient beliefs and expectations in the consultation.

The discordance between clinical and radiographic knee osteoarthritis: a systematic search and summary of the literature (2008)
Journal Article
(2008). The discordance between clinical and radiographic knee osteoarthritis: a systematic search and summary of the literature. BMC Musculoskeletal Disorders, 116 -?. https://doi.org/10.1186/1471-2474-9-116

BACKGROUND: Studies have suggested that the symptoms of knee osteoarthritis (OA) are rather weakly associated with radiographic findings and vice versa. Our objectives were to identify estimates of the prevalence of radiographic knee OA in adults wit... Read More about The discordance between clinical and radiographic knee osteoarthritis: a systematic search and summary of the literature.

Gender difference in symptomatic radiographic knee osteoarthritis in the Knee Clinical Assessment--CAS(K): a prospective study in the general population (2008)
Journal Article
(2008). Gender difference in symptomatic radiographic knee osteoarthritis in the Knee Clinical Assessment--CAS(K): a prospective study in the general population. BMC Musculoskeletal Disorders, 82 -?. https://doi.org/10.1186/1471-2474-9-82

BACKGROUND: A recent study of adults aged >or=50 years reporting knee pain found an excess of radiographic knee osteoarthritis (knee ROA) in symptomatic males compared to females. This was independent of age, BMI and other clinical signs and symptoms... Read More about Gender difference in symptomatic radiographic knee osteoarthritis in the Knee Clinical Assessment--CAS(K): a prospective study in the general population.

A cross sectional study of requests for knee radiographs from primary care (2007)
Journal Article
Bedson, J., Jordan, K. P., & Croft, P. R. (2007). A cross sectional study of requests for knee radiographs from primary care. BMC Musculoskeletal Disorders, Article 77. https://doi.org/10.1186/1471-2474-8-77

BACKGROUND: Knee pain is the commonest pain complaint amongst older adults in general practice. General Practitioners (GPs) may use x rays when managing knee pain, but little information exists regarding this process. Our objectives, therefore, were... Read More about A cross sectional study of requests for knee radiographs from primary care.

Constructing osteoarthritis through discourse: a qualitative analysis of six patient information leaflets on osteoarthritis (2007)
Journal Article
(2007). Constructing osteoarthritis through discourse: a qualitative analysis of six patient information leaflets on osteoarthritis. BMC Musculoskeletal Disorders, https://doi.org/10.1186/1471-2474-8-34

Background
Health service policy in the United Kingdom emphasises the importance of self-care by patients with chronic conditions. Written information for patients about their condition is seen as an important aid to help patients look after themsel... Read More about Constructing osteoarthritis through discourse: a qualitative analysis of six patient information leaflets on osteoarthritis.

Achilles tendon rupture following surgical management for tendinopathy: a case report (2007)
Journal Article
(2007). Achilles tendon rupture following surgical management for tendinopathy: a case report. BMC Musculoskeletal Disorders, 19 -?. https://doi.org/10.1186/1471-2474-8-19

BACKGROUND: Achilles tendinopathy is understood to be a failed healing response. Operative management is utilised following the failure of non-operative methods. CASE PRESENTATION: We present a case of Achilles tendon rupture, sustained whilst isomet... Read More about Achilles tendon rupture following surgical management for tendinopathy: a case report.

Effects of glutathione S-transferase M1, T1 and P1 on lung function in asthmatic families. (2005)
Journal Article
Carroll, W., Lenney, W., Jones, P., Strange, R., Child, F., Whyte, M., …Fryer, A. (2005). Effects of glutathione S-transferase M1, T1 and P1 on lung function in asthmatic families. Clinical and Experimental Allergy, 35(9), 1155 - 1161. https://doi.org/10.1111/j.1365-2222.2005.02313.x

RATIONALE: Previous data have suggested that glutathione-S-transferase (GST) genotypes are important in determining the rate of lung function growth in childhood. This effect was most marked in Caucasian children with asthma. OBJECTIVES: We investiga... Read More about Effects of glutathione S-transferase M1, T1 and P1 on lung function in asthmatic families..

Maternal glutathione S-transferase GSTP1 genotype is a specific predictor of phenotype in children with asthma. (2005)
Journal Article
Carroll, W., Lenney, W., Child, F., Strange, R., Jones, P., & Fryer, A. (2005). Maternal glutathione S-transferase GSTP1 genotype is a specific predictor of phenotype in children with asthma. Pediatric Allergy and Immunology, 16(1), 32 - 39. https://doi.org/10.1111/j.1399-3038.2005.00249.x

Maternal factors are known to influence the heritability and expression of asthma and atopy. We report the association of maternal, paternal and proband GSTP1 genotype with lung function in 145 Caucasian children with asthma. GSTP1 Val105/Val105 and... Read More about Maternal glutathione S-transferase GSTP1 genotype is a specific predictor of phenotype in children with asthma..

The Knee Clinical Assessment Study--CAS(K). A prospective study of knee pain and knee osteoarthritis in the general population (2004)
Journal Article
(2004). The Knee Clinical Assessment Study--CAS(K). A prospective study of knee pain and knee osteoarthritis in the general population. BMC Musculoskeletal Disorders, 4 -?. https://doi.org/10.1186/1471-2474-5-4

BACKGROUND: Knee pain affects an estimated 25% of the adult population aged 50 years and over. Osteoarthritis is the most common diagnosis made in older adults consulting with knee pain in primary care. However, the relationship between this diagnosi... Read More about The Knee Clinical Assessment Study--CAS(K). A prospective study of knee pain and knee osteoarthritis in the general population.

The North Staffordshire Osteoarthritis Project--NorStOP: prospective, 3-year study of the epidemiology and management of clinical osteoarthritis in a general population of older adults (2004)
Journal Article
(2004). The North Staffordshire Osteoarthritis Project--NorStOP: prospective, 3-year study of the epidemiology and management of clinical osteoarthritis in a general population of older adults. BMC Musculoskeletal Disorders, 2 -?. https://doi.org/10.1186/1471-2474-5-2

BACKGROUND: The clinical syndrome of joint pain and stiffness in older people is the commonest cause of disability and health care consultation in this age group. Yet there have been few prospective studies of its course over time and its impact on p... Read More about The North Staffordshire Osteoarthritis Project--NorStOP: prospective, 3-year study of the epidemiology and management of clinical osteoarthritis in a general population of older adults.

Epithelial ovarian cancer: influence of polymorphism at the glutathione S-transferase GSTM1 and GSTT1 loci on p53 expression (1996)
Journal Article
Sarhanis, P., Redman, C., Perrett, C., Brannigan, K., Clayton, R., Hand, P., …Strange, R. (1996). Epithelial ovarian cancer: influence of polymorphism at the glutathione S-transferase GSTM1 and GSTT1 loci on p53 expression. British journal of cancer, 1757 - 1761. https://doi.org/10.1038/bjc.1996.626

The importance of polymorphism in the glutathione S-transferase GSTM1, GSTT1 and, cytochrome P450, CYP2D6 loci in the pathogenesis of epithelial ovarian cancer has been assessed in two studies; firstly, a case-control study designed to determine the... Read More about Epithelial ovarian cancer: influence of polymorphism at the glutathione S-transferase GSTM1 and GSTT1 loci on p53 expression.

Identifying and rectifying prescriptions of long-acting antimuscarinic and beta-agonist inhalers without inhaled corticosteroids to asthma patients: an audit from a UK general practice surgery
Presentation / Conference
Identifying and rectifying prescriptions of long-acting antimuscarinic and beta-agonist inhalers without inhaled corticosteroids to asthma patients: an audit from a UK general practice surgery. Presented at BJGP Research Conference

Background In the UK 5.4 million people receive treatment for asthma. Patients diagnosed with asthma should not be prescribed a long-acting muscarinic antagonist (LAMA), or a long-acting beta 2 agonist (LABA) without co-prescription of an inhaled cor... Read More about Identifying and rectifying prescriptions of long-acting antimuscarinic and beta-agonist inhalers without inhaled corticosteroids to asthma patients: an audit from a UK general practice surgery.

Screening for cardiovascular disease in Rheumatoid Arthritis: a records-based investigation
Thesis
(2013). Screening for cardiovascular disease in Rheumatoid Arthritis: a records-based investigation

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease affecting approximately 1% of the population. The life expectancy of those with RA is reduced, mainly due to an increased risk of cardiovascular disease (CVD). This thesis investi... Read More about Screening for cardiovascular disease in Rheumatoid Arthritis: a records-based investigation.

The positive predictive value of postmenopausal bleeding for uterine malignancy
Thesis
(2013). The positive predictive value of postmenopausal bleeding for uterine malignancy

Postmenopausal bleeding (PMB) is vaginal bleeding occurring after the menopause. The differing definitions of PMB used and need for a standard definition, including what this might be, are highlighted in the thesis. Benign and malignant causes of PMB... Read More about The positive predictive value of postmenopausal bleeding for uterine malignancy.

STarTBack Whiteboard
Digital Artefact
(2021). STarTBack Whiteboard

Video evidence support for Impact on REF.

Interventions for the Management of Distal Intestinal Obstruction Syndrome in Cystic Fibrosis
Thesis
(2017). Interventions for the Management of Distal Intestinal Obstruction Syndrome in Cystic Fibrosis

Distal intestinal obstruction syndrome (DIOS) is a major gastrointestinal complication in cystic fibrosis (CF). It arises when thick mucus and viscid faecal material combine in the bowel, commonly at the terminal ileum or caecum, leading to partial o... Read More about Interventions for the Management of Distal Intestinal Obstruction Syndrome in Cystic Fibrosis.