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The North Staffordshire Osteoarthritis Project--NorStOP: prospective, 3-year study of the epidemiology and management of clinical osteoarthritis in a general population of older adults (2004)
Journal Article
(2004). The North Staffordshire Osteoarthritis Project--NorStOP: prospective, 3-year study of the epidemiology and management of clinical osteoarthritis in a general population of older adults. BMC Musculoskeletal Disorders, 2 -?. https://doi.org/10.1186/1471-2474-5-2

BACKGROUND: The clinical syndrome of joint pain and stiffness in older people is the commonest cause of disability and health care consultation in this age group. Yet there have been few prospective studies of its course over time and its impact on p... Read More about The North Staffordshire Osteoarthritis Project--NorStOP: prospective, 3-year study of the epidemiology and management of clinical osteoarthritis in a general population of older adults.

Epithelial ovarian cancer: influence of polymorphism at the glutathione S-transferase GSTM1 and GSTT1 loci on p53 expression (1996)
Journal Article
Sarhanis, P., Redman, C., Perrett, C., Brannigan, K., Clayton, R., Hand, P., …Strange, R. (1996). Epithelial ovarian cancer: influence of polymorphism at the glutathione S-transferase GSTM1 and GSTT1 loci on p53 expression. British journal of cancer, 1757 - 1761. https://doi.org/10.1038/bjc.1996.626

The importance of polymorphism in the glutathione S-transferase GSTM1, GSTT1 and, cytochrome P450, CYP2D6 loci in the pathogenesis of epithelial ovarian cancer has been assessed in two studies; firstly, a case-control study designed to determine the... Read More about Epithelial ovarian cancer: influence of polymorphism at the glutathione S-transferase GSTM1 and GSTT1 loci on p53 expression.

Identifying and rectifying prescriptions of long-acting antimuscarinic and beta-agonist inhalers without inhaled corticosteroids to asthma patients: an audit from a UK general practice surgery
Presentation / Conference
Identifying and rectifying prescriptions of long-acting antimuscarinic and beta-agonist inhalers without inhaled corticosteroids to asthma patients: an audit from a UK general practice surgery. Presented at BJGP Research Conference

Background In the UK 5.4 million people receive treatment for asthma. Patients diagnosed with asthma should not be prescribed a long-acting muscarinic antagonist (LAMA), or a long-acting beta 2 agonist (LABA) without co-prescription of an inhaled cor... Read More about Identifying and rectifying prescriptions of long-acting antimuscarinic and beta-agonist inhalers without inhaled corticosteroids to asthma patients: an audit from a UK general practice surgery.

Screening for cardiovascular disease in Rheumatoid Arthritis: a records-based investigation
Thesis
(2013). Screening for cardiovascular disease in Rheumatoid Arthritis: a records-based investigation

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease affecting approximately 1% of the population. The life expectancy of those with RA is reduced, mainly due to an increased risk of cardiovascular disease (CVD). This thesis investi... Read More about Screening for cardiovascular disease in Rheumatoid Arthritis: a records-based investigation.

The positive predictive value of postmenopausal bleeding for uterine malignancy
Thesis
(2013). The positive predictive value of postmenopausal bleeding for uterine malignancy

Postmenopausal bleeding (PMB) is vaginal bleeding occurring after the menopause. The differing definitions of PMB used and need for a standard definition, including what this might be, are highlighted in the thesis. Benign and malignant causes of PMB... Read More about The positive predictive value of postmenopausal bleeding for uterine malignancy.

STarTBack Whiteboard
Digital Artefact
(2021). STarTBack Whiteboard

Video evidence support for Impact on REF.

Interventions for the Management of Distal Intestinal Obstruction Syndrome in Cystic Fibrosis
Thesis
(2017). Interventions for the Management of Distal Intestinal Obstruction Syndrome in Cystic Fibrosis

Distal intestinal obstruction syndrome (DIOS) is a major gastrointestinal complication in cystic fibrosis (CF). It arises when thick mucus and viscid faecal material combine in the bowel, commonly at the terminal ileum or caecum, leading to partial o... Read More about Interventions for the Management of Distal Intestinal Obstruction Syndrome in Cystic Fibrosis.

An epidemiological study of self-care restriction and joint pain in community-dwelling older people
Thesis
(2013). An epidemiological study of self-care restriction and joint pain in community-dwelling older people

Self-care restriction is proposed in the World Health Organization’s International Classification of Functioning (ICF) as an important functional consequence of health conditions. In contrast to traditional approaches which focus only on an individua... Read More about An epidemiological study of self-care restriction and joint pain in community-dwelling older people.

Polymyalgia rheumatica in primary care: an exploration of the challenges of diagnosis and management using survey and qualitative methods
Thesis
Helliwell, T. (2016). Polymyalgia rheumatica in primary care: an exploration of the challenges of diagnosis and management using survey and qualitative methods

Background: Polymyalgia rheumatica (PMR) is one of the most common inflammatory arthritic disorders seen in older people and is closely related to giant cell arteritis (GCA). Most PMR patients are diagnosed and managed in general practice yet primary... Read More about Polymyalgia rheumatica in primary care: an exploration of the challenges of diagnosis and management using survey and qualitative methods.

Health-related quality of life in gout: a primary care-based mixed methods study
Thesis
Chandratre, P. N. (2015). Health-related quality of life in gout: a primary care-based mixed methods study

Background: Gout is the most prevalent inflammatory arthritis (2.5%) and may affect Health Related Quality Of Life (HRQOL) through its disease features, associated co-morbid and sociodemographic characteristics.

Methods: A systematic review of HRQ... Read More about Health-related quality of life in gout: a primary care-based mixed methods study.

Does Multimorbidity Influence the Outcomes of Total Hip Replacement for Osteoarthritis?
Presentation / Conference
Yu, D., & Jordan, K. P. Does Multimorbidity Influence the Outcomes of Total Hip Replacement for Osteoarthritis?. Presented at 2021 Association of Surgeons in Training International Surgical Conference

Introduction Limited data are available on the influence of multimorbidity on the outcomes of total hip replacement for patients with hip osteoarthritis, including the rate of complications and degree of functional benefit. The aim of this study was... Read More about Does Multimorbidity Influence the Outcomes of Total Hip Replacement for Osteoarthritis?.

A SYSTEMATIC REVIEW OF INTERNATIONAL GUIDELINES REGARDING THE ROLE OF RADIOGRAPHY IN THE DIAGNOSIS OF OSTEOARTHRITIS
Presentation / Conference
Henry-Blake, C., Treadwell, K., Parmar, S., Higgs, J., Marshall, M., Edwards, J., & Peat, G. A SYSTEMATIC REVIEW OF INTERNATIONAL GUIDELINES REGARDING THE ROLE OF RADIOGRAPHY IN THE DIAGNOSIS OF OSTEOARTHRITIS. Poster presented at EULAR 2021

Background: A substantial proportion of primary care osteoarthritis (OA) consultations are associated with an X-ray request (1,2). Uncertainty exists regarding the ability of radiography to improve a clinical OA diagnosis, and the over-use of radiogr... Read More about A SYSTEMATIC REVIEW OF INTERNATIONAL GUIDELINES REGARDING THE ROLE OF RADIOGRAPHY IN THE DIAGNOSIS OF OSTEOARTHRITIS.

SEX DIFFERENCES IN HIGH-RISK BUT INDICATED CORONARY INTERVENTIONS. NATIONAL REPORT FROM THE BRITISH CARDIOVASCULAR INTERVENTION SOCIETY REGISTRY
Presentation / Conference
Mamas, & Rashid. SEX DIFFERENCES IN HIGH-RISK BUT INDICATED CORONARY INTERVENTIONS. NATIONAL REPORT FROM THE BRITISH CARDIOVASCULAR INTERVENTION SOCIETY REGISTRY. Presented at ACC.22

Background: Complex and high-risk but indicated percutaneous coronary intervention (CHiP) is increasingly common in contemporary PCI practice. Data on sex differences in the type of CHiP procedures undertaken or their associated clinical outcomes are... Read More about SEX DIFFERENCES IN HIGH-RISK BUT INDICATED CORONARY INTERVENTIONS. NATIONAL REPORT FROM THE BRITISH CARDIOVASCULAR INTERVENTION SOCIETY REGISTRY.

P060 Living with rheumatoid arthritis during the coronavirus pandemic: a longitudinal interview study
Presentation / Conference
Campbell, P., Paskins, Z., Hider, S., Hassell, A., Crawford-Manning, F., Rule, K., …Ryan, S. P060 Living with rheumatoid arthritis during the coronavirus pandemic: a longitudinal interview study. Poster presented at British Society for Rheumatology Annual Conference

Background/Aims The COVID-19 pandemic placed patients with rheumatoid arthritis (RA) at increased risk of poor outcomes as a result of their condition, compounded by use of immunosuppressant medication, and higher prevalence of comorbidities. As a co... Read More about P060 Living with rheumatoid arthritis during the coronavirus pandemic: a longitudinal interview study.

The potential of closed circuit lung clearance index (LCI) to provide longitudinal clinical utility in cystic fibrosis (CF)
Presentation / Conference
Gilchrist. The potential of closed circuit lung clearance index (LCI) to provide longitudinal clinical utility in cystic fibrosis (CF). Presented at https://erj.ersjournals.com/content/54/suppl_63/PA332

Background: Closed circuit washin offers a quicker test with the advantages of an exogenous tracer to measure FRC and LCI. We measured LCI in CF paediatric and adult outpatient clinics to assess repeatability of LCI and track changes over time, and i... Read More about The potential of closed circuit lung clearance index (LCI) to provide longitudinal clinical utility in cystic fibrosis (CF).