Exploring a Gemcitabine-Glucose Hybrid as a Glycoconjugate Prodrug (2024)
Journal Article
Porter, J., Noble, A. R., Signoret, N., Fascione, M. A., & Miller, G. J. (in press). Exploring a Gemcitabine-Glucose Hybrid as a Glycoconjugate Prodrug. ACS Omega, 9(29), 31703-31713. https://doi.org/10.1021/acsomega.4c02417

Nucleoside analogues are established treatments for cancer and viral infection. Gemcitabine is a commonly employed nucleoside analogue displaying anticancer properties against a range of tumor types but is rapidly inactivated in vivo. Efforts to bols... Read More about Exploring a Gemcitabine-Glucose Hybrid as a Glycoconjugate Prodrug.

Advances in biocatalytic and chemoenzymatic synthesis of nucleoside analogues. (2022)
Journal Article
Cosgrove, S. C., & Miller, G. J. (2022). Advances in biocatalytic and chemoenzymatic synthesis of nucleoside analogues. Expert Opinion on Drug Discovery, 17(4), 355-364. https://doi.org/10.1080/17460441.2022.2039620

INTRODUCTION: Nucleoside analogues represent a cornerstone of achievement in drug discovery, rising to prominence particularly in the fields of antiviral and anticancer discovery over the last 60 years. Traditionally accessed using chemical synthesis... Read More about Advances in biocatalytic and chemoenzymatic synthesis of nucleoside analogues..

Sweet targets: sugar nucleotide biosynthesis inhibitors. (2022)
Journal Article
Ahmadipour, S., Reynisson, J., Field, R. A., & Miller, G. J. (2022). Sweet targets: sugar nucleotide biosynthesis inhibitors. Future Medicinal Chemistry, 14(5), 295-298. https://doi.org/10.4155/fmc-2021-0286

'Editorial Material'

Exploring anomeric glycosylation of phosphoric acid: Optimisation and scope for non-native substrates. (2019)
Journal Article
Beswick, L., Ahmadipour, S., Hofman, G., Wootton, H., Dimitriou, E., Reynisson, J., …Miller, G. J. (2020). Exploring anomeric glycosylation of phosphoric acid: Optimisation and scope for non-native substrates. Carbohydrate Research, 488, 107896. https://doi.org/10.1016/j.carres.2019.107896

'No abstract'

Money Versus Medicine: Public Perceptions of Patenting Medical Innovations (2019)
Journal Article
(2019). Money Versus Medicine: Public Perceptions of Patenting Medical Innovations. https://doi.org/10.21252/nr13-a922

The effect of demographics on the public's perceptions of the pharmaceutical industry, and the subsequent influence this has on over-the-counter painkiller buying preference, is a sparsely researched area. At the time of publication, there had been n... Read More about Money Versus Medicine: Public Perceptions of Patenting Medical Innovations.