Is it time for biocatalysis in fragment-based drug discovery? (2020)
Journal Article
Cosgrove. (2020). Is it time for biocatalysis in fragment-based drug discovery?. Chemical Science, 11104 - 11112. https://doi.org/10.1039/D0SC04103C

The use of biocatalysts for fragment-based drug discovery has yet to be fully investigated, despite the promise enzymes hold for the synthesis of poly-functional, non-protected small molecules. Here we analyze products of the biocatalysis literature... Read More about Is it time for biocatalysis in fragment-based drug discovery?.

Age-Related Trends in the Trabecular Micro-Architecture of the Medial Clavicle: Is It of Use in Forensic Science? (2020)
Journal Article
McGivern, H., Greenwood, C., Márquez-Grant, N., Kranioti, E., Xhemali, B., & Zioupos, P. (2020). Age-Related Trends in the Trabecular Micro-Architecture of the Medial Clavicle: Is It of Use in Forensic Science?. Frontiers in Bioengineering and Biotechnology, 7, https://doi.org/10.3389/fbioe.2019.00467

The mechanical and structural properties of bone are known to change significantly with age. Within forensic and archaeological investigations, the medial end of the clavicle is typically used for estimating the age-at-death of an unknown individual.... Read More about Age-Related Trends in the Trabecular Micro-Architecture of the Medial Clavicle: Is It of Use in Forensic Science?.

The use of µCT and fractal dimension for fracture prediction in osteoporotic individuals (2019)
Journal Article
Arnold, E., Clement, J., Rogers, K., Garcia-Castro, F., & Greenwood, C. (2020). The use of µCT and fractal dimension for fracture prediction in osteoporotic individuals. Journal of the Mechanical Behavior of Biomedical Materials, 103, Article 103585. https://doi.org/10.1016/j.jmbbm.2019.103585

Osteoporosis (OP) is a widespread condition with commonly associated fracture sites at the hip, vertebra and wrist. This study examines the effects of age and osteoporosis on bone quality by comparing the efficacy of using parameters which indicate b... Read More about The use of µCT and fractal dimension for fracture prediction in osteoporotic individuals.