The thermal expansion properties of halogen bond containing 1-4 dioxane halogen complexes. (2019)
Journal Article
Jones. (2019). The thermal expansion properties of halogen bond containing 1-4 dioxane halogen complexes. CrystEngComm, 5269-5277. https://doi.org/10.1039/C9CE00803A

Neutron powder diffraction has been used to determine accurate molecular structures and thermal expansion properties for the complexes formed between by iodine and bromine with 1{,}4 dioxane. The marked anisotropy in the magnitudes of the principal a... Read More about The thermal expansion properties of halogen bond containing 1-4 dioxane halogen complexes..

Chemical and enzymatic synthesis of the alginate sugar nucleotide building block: GDP-d-mannuronic acid (2019)
Journal Article
Beswick, L., Ahmadipour, S., Dolan, J. P., Rejzek, M., Field, R. A., & Miller, G. J. (2019). Chemical and enzymatic synthesis of the alginate sugar nucleotide building block: GDP-d-mannuronic acid. Carbohydrate Research, 485(1), 107819 -107819. https://doi.org/10.1016/j.carres.2019.107819

Highlights

Sugarnucleotide synthesis.

Chemical and enzymatic access to GDP-d-ManA.

Evaluation of protected and free uronate 1-phosphates for pyrophosphorylation.

External surface phenomena in dealumination and desilication of large single crystals of ZSM-5 zeolite synthesized from a sustainable source (2019)
Journal Article
Zholobenko, V., de Melo, J., Peron, D., Khodakov, A., Capron, M., Nuns, N., de Souza, M., Feris, L., Marcilio, N., & Ordomsky, V. (2019). External surface phenomena in dealumination and desilication of large single crystals of ZSM-5 zeolite synthesized from a sustainable source. Microporous and Mesoporous Materials, 57-64. https://doi.org/10.1016/j.micromeso.2019.05.033

Zeolite dealumination and desilication are common methods, which improve accessibility of the active sites located inside the zeolite crystallites and tune the zeolite acidity. The exact mechanism of these post-synthesis zeolite treatments remains un... Read More about External surface phenomena in dealumination and desilication of large single crystals of ZSM-5 zeolite synthesized from a sustainable source.

Synthesis, coordination chemistry and photophysical properties of naphtho-fused pyrazole ligands (2019)
Journal Article
Hawes, C. S. (2019). Synthesis, coordination chemistry and photophysical properties of naphtho-fused pyrazole ligands. CrystEngComm, 5152-5163. https://doi.org/10.1039/c9ce01074b

The synthesis of two p-extended pyrazole ligands is reported, with naphtho[2,1-d]-1H-pyrazole HL1 prepared in a modified Jacobson indazole synthesis from 1-amino-2-methylnaphthalene, and subsequent arylation with 2-bromopyridine giving the chelating... Read More about Synthesis, coordination chemistry and photophysical properties of naphtho-fused pyrazole ligands.

The influence of precursors on the induction period and transition-regime of dimethyl ether conversion to hydrocarbons over ZSM-5 catalysts (2019)
Journal Article
Omojola, T., Lukyanov, D., Cherkasov, N., Zholobenko, V., & van Veen, A. (2019). The influence of precursors on the induction period and transition-regime of dimethyl ether conversion to hydrocarbons over ZSM-5 catalysts. Industrial & Engineering Chemistry Research, 16479-16488. https://doi.org/10.1021/acs.iecr.9b03344

ZSM-5 catalysts were subjected to step response cycles of dimethyl ether (DME) at 300 °C in a temporal analysis of products (TAP) reactor. Propylene is the major olefin and displays an S-shaped profile. A 44-min induction period occurs before primary... Read More about The influence of precursors on the induction period and transition-regime of dimethyl ether conversion to hydrocarbons over ZSM-5 catalysts.

Phenotypic Plasticity of Nest-Mate Recognition Cues in Formica exsecta Ants. (2019)
Journal Article
Martin, S. J., Drijfhout, F. P., & Hart, A. G. (2019). Phenotypic Plasticity of Nest-Mate Recognition Cues in Formica exsecta Ants. Journal of Chemical Ecology, 735 -740. https://doi.org/10.1007/s10886-019-01103-2

It is well established that many ant species have evolved qualitatively distinct species-specific chemical profile that are stable over large geographical distances. Within these species profiles quantitative variations in the chemical profile allows... Read More about Phenotypic Plasticity of Nest-Mate Recognition Cues in Formica exsecta Ants..

ChemScapes: an Adaptable Chemistry Escape Room Challenge (2019)
Presentation / Conference
Haxton, K. (2019, August). ChemScapes: an Adaptable Chemistry Escape Room Challenge. Presented at ariety in Chemistry Education / Physics Higher Education Conference 2019, Bristol

Escape rooms are increasing in popularity and the basic premise lends itself well to outreach activities: complete tasks to obtain clues and escape the room. We have adapted the format for use in a laboratory setting, creating a set of challenges tha... Read More about ChemScapes: an Adaptable Chemistry Escape Room Challenge.

Unexpected linkage isomerism in chiral tetranuclear bis-tridentate (1,2,3-triazol-4-yl)-picolinamide (tzpa) grids (2019)
Journal Article
Hegarty, I. N., Dalton, H. L., Henwood, A. F., Hawes, C. S., & Gunnlaugsson, T. (2019). Unexpected linkage isomerism in chiral tetranuclear bis-tridentate (1,2,3-triazol-4-yl)-picolinamide (tzpa) grids. Chemical Communications, 9523-9526. https://doi.org/10.1039/c9cc03316e

The synthesis of a chiral bis-tridentate (1,2,3-triazol-4-yl)-picolinamide (tzpa) ligand is described and its coordination chemistry with Cu(NO3)2 and [Cu(MeCN)4]PF6 is explored in the crystalline phase as well as in solution. Chiral [2 × 2] tetranuc... Read More about Unexpected linkage isomerism in chiral tetranuclear bis-tridentate (1,2,3-triazol-4-yl)-picolinamide (tzpa) grids.

Crude Heparin Preparations Unveil the Presence of Structurally Diverse Oversulfated Contaminants (2019)
Journal Article
Mendes, A., Meneghetti, M., Palladino, M., Justo, G., Sassaki, G., Fareed, J., Andrade De Lima, M., & Nader, H. (2019). Crude Heparin Preparations Unveil the Presence of Structurally Diverse Oversulfated Contaminants. Molecules, 24, 2988--2988. https://doi.org/10.3390/molecules24162988

Nowadays, pharmaceutical heparin is purified from porcine and bovine intestinal mucosa. In the past decade there has been an ongoing concern about the safety of heparin, since in 2008, adverse effects associated with the presence of an oversulfated c... Read More about Crude Heparin Preparations Unveil the Presence of Structurally Diverse Oversulfated Contaminants.

An ab initio study of the valence tautomerism of type B mesoionic rings (2019)
Journal Article
(2019). An ab initio study of the valence tautomerism of type B mesoionic rings. Tetrahedron Letters, https://doi.org/10.1016/j.tetlet.2019.06.035

The MP2 calculated Gibbs free energies of a series of type B mesoionic rings and their acyclic valence tautomers suggest that in the gas phase the relative stability of the mesoionic ring increases with single bond strength (S-S > RN-NR > O-O). Inclu... Read More about An ab initio study of the valence tautomerism of type B mesoionic rings.

The size of micro-crystalline tyrosine (MCT®) influences its recognition and uptake by THP-1 macrophages in vitro (2019)
Journal Article
(2019). The size of micro-crystalline tyrosine (MCT®) influences its recognition and uptake by THP-1 macrophages in vitro. RSC advances, 24505 - 24518. https://doi.org/10.1039/C9RA03831K

The physicochemical hallmarks of particulate immunopotentiators play a pivotal role with regards to their adjuvanticity in vivo. These properties have not been fully characterised in the case of MCT®, an amino acid-based adjuvant used as an alternati... Read More about The size of micro-crystalline tyrosine (MCT®) influences its recognition and uptake by THP-1 macrophages in vitro.

Peptide Cross-Linked Poly(2-oxazoline) as a Sensor Material for the Detection of Proteases with a Quartz Crystal Microbalance (2019)
Journal Article
Watkinson. (2019). Peptide Cross-Linked Poly(2-oxazoline) as a Sensor Material for the Detection of Proteases with a Quartz Crystal Microbalance. Biomacromolecules, 2506-2514. https://doi.org/10.1021/acs.biomac.9b00245

Inflammatory conditions are frequently accompanied by increased levels of active proteases, and there is rising interest in methods for their detection to monitor inflammation in a point of care setting. In this work, new sensor materials for disposa... Read More about Peptide Cross-Linked Poly(2-oxazoline) as a Sensor Material for the Detection of Proteases with a Quartz Crystal Microbalance.

Developing Scientific Reporting Skills of Early Undergraduate Chemistry Students (2019)
Book Chapter
Capel, N. J., Hancock, L. M., Haxton, K. J., Hollamby, M. J., Jones, R. H., Plana, D., & Mcgarvey, D. J. (2019). Developing Scientific Reporting Skills of Early Undergraduate Chemistry Students. In Teaching Chemistry in Higher Education: A Festschrift in Honour of Professor Tina Overton (333 - 333 (348)). Creathach Press

Our aim is to initiate the development of selected generic skills of early undergraduate chemistry students by focussing on scientific reporting skills. To achieve this, we have developed an approach that draws upon chemistry journal articles as para... Read More about Developing Scientific Reporting Skills of Early Undergraduate Chemistry Students.

Undergraduate screencast presentations with self-, peer-, and tutor-assessment (2019)
Book Chapter
Haxton. (2019). Undergraduate screencast presentations with self-, peer-, and tutor-assessment. In Teaching Chemistry in Higher Education (265 - 282)

The aim of this work is to describe the use of screencast presentations with first year undergraduate chemistry students to enable presentations to take place without significant timetable demands. I also describe self- and peer- assessment protocols... Read More about Undergraduate screencast presentations with self-, peer-, and tutor-assessment.

A carbon deposition and sulphur poisoning study of new pyrochlore catalysts for methane reforming (2019)
Thesis
Alfatlawi, Z. K. A carbon deposition and sulphur poisoning study of new pyrochlore catalysts for methane reforming. (Thesis). Keele University. https://keele-repository.worktribe.com/output/413837

Reforming of landfill gases for the production of syngas that leads to the generation of heat or electricity is a very promising pathway considering the increasing price of oil. The dry reforming technique is a very interesting approach to reduce the... Read More about A carbon deposition and sulphur poisoning study of new pyrochlore catalysts for methane reforming.

6R/S-deutero-a-d-mannopyranoside 1-phosphate (2019)
Journal Article
Miller, G., & Ahmadipour, S. (2019). 6R/S-deutero-a-d-mannopyranoside 1-phosphate. Molbank, 2019(3), Article M1068. https://doi.org/10.3390/M1068

6R/S-deutero-a-d-mannopyranoside 1-phosphate was synthesised from a C6 aldehydic mannose thioglycoside donor in four steps. Using NaBD4 as the reductant, isotopic enrichment at C6 was achieved and the resultant C6-deuterated material was converted th... Read More about 6R/S-deutero-a-d-mannopyranoside 1-phosphate.

Versatile Roles of Metal Species in Carbon Nanotube Templates for the Synthesis of Metal-Zeolite Nanocomposite Catalysts (2019)
Journal Article
(2019). Versatile Roles of Metal Species in Carbon Nanotube Templates for the Synthesis of Metal-Zeolite Nanocomposite Catalysts. ACS Applied Nano Material, 4507-4517. https://doi.org/10.1021/acsanm.9b00888

Metal-zeolite nanocomposites are extensively used in heterogeneous catalysis. The small size of zeolite micropores and non-uniform distribution of the metal component within the zeolite structure can severely reduce the efficiency of these catalysts.... Read More about Versatile Roles of Metal Species in Carbon Nanotube Templates for the Synthesis of Metal-Zeolite Nanocomposite Catalysts.

Ln3+ doping in CaYAl3O7 and luminescence concentration quenching studied via a new computer modelling strategy (2019)
Journal Article
Jackson. (2019). Ln3+ doping in CaYAl3O7 and luminescence concentration quenching studied via a new computer modelling strategy. Optical Materials, 212-216. https://doi.org/10.1016/j.optmat.2019.04.036

Ln-doped CaYAl3O7 (CYAM) has several applications due to its optical properties. This crystal matrix belongs to the melilite family, where Ca2+/Y3+ ions are randomly distributed at the same crystallographic site keeping a composition ratio of 1:1. Th... Read More about Ln3+ doping in CaYAl3O7 and luminescence concentration quenching studied via a new computer modelling strategy.

A Glycosaminoglycan Extract from Portunus pelagicus Inhibits BACE1, the β Secretase Implicated in Alzheimer's Disease. (2019)
Journal Article
Mycroft-West, C., Cooper, L., Devlin, A., Procter, P., Guimond, S., Guerrini, M., Fernig, D., Lima, M., Yates, E., & Skidmore, M. (2019). A Glycosaminoglycan Extract from Portunus pelagicus Inhibits BACE1, the β Secretase Implicated in Alzheimer's Disease. Marine Drugs, 17, 293 -293. https://doi.org/10.3390/md17050293

Therapeutic options for Alzheimer's disease, the most common form of dementia, are currently restricted to palliative treatments. The glycosaminoglycan heparin, widely used as a clinical anticoagulant, has previously been shown to inhibit the Alzheim... Read More about A Glycosaminoglycan Extract from Portunus pelagicus Inhibits BACE1, the β Secretase Implicated in Alzheimer's Disease..

Photoelectrochemical Imaging System for the Mapping of Cell Surface Charges (2019)
Journal Article
Watkinson. (2019). Photoelectrochemical Imaging System for the Mapping of Cell Surface Charges. Analytical Chemistry, 5896 -5903. https://doi.org/10.1021/acs.analchem.9b00304

The surface charge of cells affects cell signaling, cell metabolic processes, adherence to surfaces, and cell proliferation. Our understanding of the role of membrane charges is limited due to the inability to observe changes without interfering, che... Read More about Photoelectrochemical Imaging System for the Mapping of Cell Surface Charges.