Opposing effects of final population density and stress on Escherichia coli mutation rate (2018)
Journal Article
Channon. (2018). Opposing effects of final population density and stress on Escherichia coli mutation rate. ISME Journal, 2981-2987. https://doi.org/10.1038/s41396-018-0237-3

Evolution depends on mutations. For an individual genotype, the rate at which mutations arise is known to increase with various stressors (stress-induced mutagenesis-SIM) and decrease at high final population density (density-associated mutation-rate... Read More about Opposing effects of final population density and stress on Escherichia coli mutation rate.

Critical Mutation Rate has an Exponential Dependence on Population Size for Eukaryotic-length Genomes with Crossover (2017)
Journal Article
Channon. (2017). Critical Mutation Rate has an Exponential Dependence on Population Size for Eukaryotic-length Genomes with Crossover. Scientific reports, https://doi.org/10.1038/s41598-017-14628-x

The critical mutation rate (CMR) determines the shift between survival-of-the-fittest and survival of individuals with greater mutational robustness (“flattest”). We identify an inverse relationship between CMR and sequence length in an in silico sys... Read More about Critical Mutation Rate has an Exponential Dependence on Population Size for Eukaryotic-length Genomes with Crossover.