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Patients' and clinicians' perspectives towards primary care consultations for shoulder pain: qualitative findings from the Prognostic and Diagnostic Assessment of the Shoulder (PANDA-S) programme. (2023)
Journal Article
Saunders, B., Burton, C., van der Windt, D. A., Myers, H., Chester, R., Pincus, T., & Wynne-Jones, G. (2023). Patients' and clinicians' perspectives towards primary care consultations for shoulder pain: qualitative findings from the Prognostic and Diagnostic Assessment of the Shoulder (PANDA-S) programme. BMC Musculoskeletal Disorders, 24, Article 1. https://doi.org/10.1186/s12891-022-06059-1

BACKGROUND: Clinical management of musculoskeletal shoulder pain can be challenging due to diagnostic uncertainty, variable prognosis and limited evidence for long-term treatment benefits. The UK-based PANDA-S programme (Prognostic And Diagnostic Ass... Read More about Patients' and clinicians' perspectives towards primary care consultations for shoulder pain: qualitative findings from the Prognostic and Diagnostic Assessment of the Shoulder (PANDA-S) programme..

Conceptualising and measuring adherence to exercise for musculoskeletal pain: The Adherence To Exercise for Musculoskeletal Pain Tool (ATEMPT) (2022)
Thesis
Bailey, D. L. (2022). Conceptualising and measuring adherence to exercise for musculoskeletal pain: The Adherence To Exercise for Musculoskeletal Pain Tool (ATEMPT). (Thesis). Keele University

Aim: To develop and test a measurement tool for adherence to exercise for musculoskeletal (MSK) pain.

Purpose: A valid and reliable measure of adherence to exercise will improve the interpretation of whether outcomes observed in studies of exercis... Read More about Conceptualising and measuring adherence to exercise for musculoskeletal pain: The Adherence To Exercise for Musculoskeletal Pain Tool (ATEMPT).

Developing human tissue engineered arterial constructs to simulate human in vivo thrombus formation (2022)
Journal Article
Ranjbar, J., Yang, Y., & Harper, A. (2022). Developing human tissue engineered arterial constructs to simulate human in vivo thrombus formation. Platelets, 34(1), https://doi.org/10.1080/09537104.2022.2153823

Thrombus formation is highly dependent upon the physico-chemical environment in which it is triggered. Our ability to understand how thrombus formation is initiated, regulated, and resolved in the human body is dependent upon our ability to replicat... Read More about Developing human tissue engineered arterial constructs to simulate human in vivo thrombus formation.

Factors associated with change in health-related quality of life in people with gout: a 3-year prospective cohort study in primary care (2022)
Journal Article
Watson, L., Belcher, J., Nicholls, E., Chandratre, P., Blagojevic-Bucknall, M., Hider, S., …Roddy, E. (2022). Factors associated with change in health-related quality of life in people with gout: a 3-year prospective cohort study in primary care. Rheumatology, 62(8), 2748-2756. https://doi.org/10.1093/rheumatology/keac706

Objective To describe factors associated with change in health-related quality of life (HRQOL) in people living with gout in primary care. Methods In a UK prospective cohort study, adults with a diagnosis of gout registered with 20 general practices... Read More about Factors associated with change in health-related quality of life in people with gout: a 3-year prospective cohort study in primary care.

Post-infarction ventricular septal defect: percutaneous or surgical management in the UK national registry (2022)
Journal Article
Mamas. (2022). Post-infarction ventricular septal defect: percutaneous or surgical management in the UK national registry. European Heart Journal, 5020-5032. https://doi.org/10.1093/eurheartj/ehac511

Background and Aims Postinfarction ventricular septal defect (PIVSD) is a mechanical complication of myocardial infarction (MI) with a poor prognosis. Surgical repair is the mainstay of treatment, although percutaneous closure is increasingly underta... Read More about Post-infarction ventricular septal defect: percutaneous or surgical management in the UK national registry.

Open‐labelled study to monitor the effect of an amino acid formula on symptom management in children with spinal muscular atrophy type I: The SMAAF pilot study (2022)
Journal Article
Bowerman, M., O'Connor, G., Edel, L., Raquq, S., Szmurlo, A., Simpson, Z., …Baranello, G. (2023). Open‐labelled study to monitor the effect of an amino acid formula on symptom management in children with spinal muscular atrophy type I: The SMAAF pilot study. Nutrition in Clinical Practice, 38(4), 871-880. https://doi.org/10.1002/ncp.10940

Background: An increasing number of families of spinal muscular atrophy (SMA) children are incorporating an amino acid-based enteral formula into their child’s feeding regimens. Other components of the amino acidbased formula include added carbohydra... Read More about Open‐labelled study to monitor the effect of an amino acid formula on symptom management in children with spinal muscular atrophy type I: The SMAAF pilot study.

Rewriting the history of leishmaniasis in Sri Lanka: An untold story since 1904. (2022)
Journal Article
Nuwangi, H., Weerakoon, K., Agampodi, T., Price, H., Dikomitis, L., & Agampodi, S. (2022). Rewriting the history of leishmaniasis in Sri Lanka: An untold story since 1904. PLoS Neglected Tropical Diseases, e0010918 - ?. https://doi.org/10.1371/journal.pntd.0010918

Leishmaniasis is widely considered a disease that emerged in Sri Lanka in the 1990s. However, a comprehensive case report from 1904 suggests that the presence of Leishmaniasis was well demonstrated in Sri Lanka long before that. The Annual Administra... Read More about Rewriting the history of leishmaniasis in Sri Lanka: An untold story since 1904..

Enhancing authenticity, diagnosticity and equivalence (AD-Equiv) in multicentre OSCE exams in health professionals education: protocol for a complex intervention study. (2022)
Journal Article
Yeates, P., Maluf, A., Kinston, R., Cope, N., McCray, G., Cullen, K., …Wong, G. (2022). Enhancing authenticity, diagnosticity and equivalence (AD-Equiv) in multicentre OSCE exams in health professionals education: protocol for a complex intervention study. BMJ Open, 12(12), Article e064387. https://doi.org/10.1136/bmjopen-2022-064387

INTRODUCTION: Objective structured clinical exams (OSCEs) are a cornerstone of assessing the competence of trainee healthcare professionals, but have been criticised for (1) lacking authenticity, (2) variability in examiners' judgements which can cha... Read More about Enhancing authenticity, diagnosticity and equivalence (AD-Equiv) in multicentre OSCE exams in health professionals education: protocol for a complex intervention study..

Predictors of perceived risk in first-degree relatives of patients with rheumatoid arthritis. (2022)
Journal Article
Bunnewell, S., Wells, I., Zemedikun, D., Simons, G., Mallen, C. D., Raza, K., & Falahee, M. (2022). Predictors of perceived risk in first-degree relatives of patients with rheumatoid arthritis. RMD Open, https://doi.org/10.1136/rmdopen-2022-002606

OBJECTIVES: To define variables associated with perceived risk of developing rheumatoid arthritis (RA) in first-degree relatives (FDRs) of patients with RA. METHODS: Patients with RA and their FDRs were invited to complete cross-sectional surveys. FD... Read More about Predictors of perceived risk in first-degree relatives of patients with rheumatoid arthritis..

Mortality in ST-segment elevation myocardial infarction patients without standard modifiable risk factors: A race disaggregated analysis. (2022)
Journal Article
Mamas, & Rashid. (2022). Mortality in ST-segment elevation myocardial infarction patients without standard modifiable risk factors: A race disaggregated analysis. https://doi.org/10.1016/j.ijcha.2022.101135

Background: Individuals who present with STEMI without the standard cardiovascular risk factors (SMuRFs) of diabetes, hypercholesterolemia, hypertension, and smoking, coined SMuRF-less are not uncommon. Little is known about their outcomes as a cohor... Read More about Mortality in ST-segment elevation myocardial infarction patients without standard modifiable risk factors: A race disaggregated analysis..

Differential remodelling of mitochondrial subpopulations and mitochondrial dysfunction are a feature of early stage diabetes (2022)
Journal Article
Mamas. (2022). Differential remodelling of mitochondrial subpopulations and mitochondrial dysfunction are a feature of early stage diabetes. Scientific reports, https://doi.org/10.1038/s41598-022-04929-1

<jats:title>Abstract</jats:title><jats:p>Mitochondrial dysfunction is a feature of type I and type II diabetes, but there is a lack of consistency between reports and links to disease development. We aimed to investigate if mitochondrial structure–fu... Read More about Differential remodelling of mitochondrial subpopulations and mitochondrial dysfunction are a feature of early stage diabetes.

Acceptability and engagement amongst patients on oral and intravenous bisphosphonates for the treatment of osteoporosis in older adults (2022)
Journal Article
Narayanasamy, M., Bishop, S., Sahota, O., Paskins, Z., Gittoes, N., & Langley, T. (2022). Acceptability and engagement amongst patients on oral and intravenous bisphosphonates for the treatment of osteoporosis in older adults. Age and ageing, https://doi.org/10.1093/ageing/afac255

Background: Osteoporosis is common in older adults leading to fragility fractures at enormous individual and economic cost. Improving long-term adherence with bisphosphonate treatments reduces fracture risk, but adherence rates for first line oral bi... Read More about Acceptability and engagement amongst patients on oral and intravenous bisphosphonates for the treatment of osteoporosis in older adults.

Effects of the COVID-19 pandemic on secondary care for cardiovascular disease in the UK: an electronic health record analysis across three countries. (2022)
Journal Article
Wright, F. L., Cheema, K., Goldacre, R., Hall, N., Herz, N., Islam, N., …Banerjee, A. (2023). Effects of the COVID-19 pandemic on secondary care for cardiovascular disease in the UK: an electronic health record analysis across three countries. European Heart Journal - Quality of Care and Clinical Outcomes, 9(4), 377-388. https://doi.org/10.1093/ehjqcco/qcac077

Background
Although morbidity and mortality from COVID-19 have been widely reported, the indirect effects of the pandemic beyond 2020 on other major diseases and health service activity have not been well described.

Methods and results
Analyses... Read More about Effects of the COVID-19 pandemic on secondary care for cardiovascular disease in the UK: an electronic health record analysis across three countries..

Palliative Care Utilization Among Hospitalized Patients With Common Chronic Conditions in the United States. (2022)
Journal Article
Rashid, & Mamas. (2022). Palliative Care Utilization Among Hospitalized Patients With Common Chronic Conditions in the United States. Journal of Palliative Care, 8258597221136733 - ?. https://doi.org/10.1177/08258597221136733

Objective: Limited data exist around the receipt of palliative care (PC) in patients hospitalized with common chronic conditions. We studied the independent predictors, temporal trends in rates of PC utilization in patients hospitalized with acute ex... Read More about Palliative Care Utilization Among Hospitalized Patients With Common Chronic Conditions in the United States..

Sensemaking in the early stages of the COVID‐19 pandemic: A narrative exploration of polarised morality in an NHS Trust (2022)
Journal Article
Faux‐Nightingale, A., Kelemen, M., Lilley, S., & Stewart, C. (2023). Sensemaking in the early stages of the COVID‐19 pandemic: A narrative exploration of polarised morality in an NHS Trust. Sociology of Health and Illness, 45(2), 386-404. https://doi.org/10.1111/1467-9566.13586

This article presents an analysis of personal diaries kept by health-care staff within a specialist NHS Trust in England during the initial 3 months of the COVID-19 pandemic. It adopts a moral sensemaking perspective to explore how NHS employees mobi... Read More about Sensemaking in the early stages of the COVID‐19 pandemic: A narrative exploration of polarised morality in an NHS Trust.

Recommendations for improving the working conditions and cultures of distressed junior doctors, based on a qualitative study and stakeholder perspectives. (2022)
Journal Article
Chew-Graham. (2022). Recommendations for improving the working conditions and cultures of distressed junior doctors, based on a qualitative study and stakeholder perspectives. BMC Health Services Research, 1333 - ?. https://doi.org/10.1186/s12913-022-08728-2

Background: Doctors, including junior doctors, are vulnerable to greater levels of distress and mental health difficulties than the public. This is exacerbated by their working conditions and cultures. While this vulnerability has been known for many... Read More about Recommendations for improving the working conditions and cultures of distressed junior doctors, based on a qualitative study and stakeholder perspectives..

Development and external validation of a risk prediction model for falls in patients with an indication for antihypertensive treatment: retrospective cohort study. (2022)
Journal Article
Archer, L., Koshiaris, C., Lay-Flurrie, S., Snell, K. I. E., Riley, R. D., Stevens, R., …Ogden, M. (2022). Development and external validation of a risk prediction model for falls in patients with an indication for antihypertensive treatment: retrospective cohort study. BMJ, 379, e070918. https://doi.org/10.1136/bmj-2022-070918

OBJECTIVE: To develop and externally validate the STRAtifying Treatments In the multi-morbid Frail elderlY (STRATIFY)-Falls clinical prediction model to identify the risk of hospital admission or death from a fall in patients with an indication for a... Read More about Development and external validation of a risk prediction model for falls in patients with an indication for antihypertensive treatment: retrospective cohort study..