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Incidence and mortality due to thromboembolic events during the COVID-19 pandemic: Multi-sourced population-based health records cohort study. (2021)
Journal Article
Mamas, & Rashid. (2021). Incidence and mortality due to thromboembolic events during the COVID-19 pandemic: Multi-sourced population-based health records cohort study. Thrombosis Research, 17 - 23. https://doi.org/10.1016/j.thromres.2021.03.006

BACKGROUND: Evidence supports an excess of deaths during the COVID-19 pandemic. We report the incidence and mortality of thrombo-embolic events (TE) during the COVID-19 pandemic. METHODS: Multi-sourced nationwide cohort study of adults (age =18 years... Read More about Incidence and mortality due to thromboembolic events during the COVID-19 pandemic: Multi-sourced population-based health records cohort study..

Missed acute myocardial infarction: an underrecognized problem that contributes to poor patient outcomes. (2021)
Journal Article
Mallen. (2021). Missed acute myocardial infarction: an underrecognized problem that contributes to poor patient outcomes. Coronary Artery Disease, 345-349. https://doi.org/10.1097/MCA.0000000000000975

Ischemic heart disease is the number one killer in the world. While improvements in the management of acute myocardial infarction (AMI) have resulted in lower mortality rates, there are still cases where AMI is missed with rates varying depending on... Read More about Missed acute myocardial infarction: an underrecognized problem that contributes to poor patient outcomes..

Quantifying Missingness in Wearable Heart Rate Recordings (2021)
Presentation / Conference
Collins, T., Woolley, S. I., Oniani, S., & Pandyan, A. (2021, May). Quantifying Missingness in Wearable Heart Rate Recordings. Presented at Medical Informatics Europe 2021, Virtual

Wrist-worn photoplethysmography (PPG) heart rate monitoring devices are increasingly used in clinical applications despite the potential for data missingness and inaccuracy. This paper provides an analysis of the intermittency of experimental wearabl... Read More about Quantifying Missingness in Wearable Heart Rate Recordings.

Minimum sample size for external validation of a clinical prediction model with a continuous outcome (2021)
Journal Article
Riley, R. D., Debray, T. P., Collins, G. S., Archer, L., Ensor, J., van Smeden, M., & Snell, K. I. (2021). Minimum sample size for external validation of a clinical prediction model with a continuous outcome. Statistics in Medicine, 40(19), 4230-4251. https://doi.org/10.1002/sim.9025

Clinical prediction models provide individualised outcome predictions to inform patient counselling and clinical decision making. External validation is the process of examining a prediction model’s performance in data independent to that used for mo... Read More about Minimum sample size for external validation of a clinical prediction model with a continuous outcome.

Recommendations for implementing HPV self-testing in Aotearoa (2021)
Journal Article
Scott, N., Bartholomew, K., Lawton, B., Sherman, S., Bromhead, C., Grant, J., …Crengle, S. (2021). Recommendations for implementing HPV self-testing in Aotearoa. New Zealand Medical Journal, 134(1535), 11-16

In Budget 2021 published earlier this month, the Government made the welcome and long-awaited announcement that they will invest “up to $53 million to complete the design of and implement a new human papillomavirus (HPV) test” in 2023.

Clinicians’ Perspectives on Self-Harm in Pakistan: A Qualitative Study (2021)
Journal Article
Chew-Graham. (2021). Clinicians’ Perspectives on Self-Harm in Pakistan: A Qualitative Study. Frontiers in Psychiatry, https://doi.org/10.3389/fpsyt.2021.607549

Background: Suicide is a serious public health problem, ranked amongst the leading causes of death worldwide. There are no official data on self-harm and suicide in Pakistan; both are illegal acts, and are socially and religiously condemned. This stu... Read More about Clinicians’ Perspectives on Self-Harm in Pakistan: A Qualitative Study.

Corrigendum to: comparing the use of direct observation, standardized patients and exit interviews in low- and middle-income countries: a systematic review of methods of assessing quality of primary care. (2021)
Journal Article
Mallen. (2021). Corrigendum to: comparing the use of direct observation, standardized patients and exit interviews in low- and middle-income countries: a systematic review of methods of assessing quality of primary care. Health Policy and Planning, 341-356. https://doi.org/10.1093/heapol/czab046

Methodological considerations in the assessment of direct and indirect costs of back pain: A systematic scoping review (2021)
Journal Article
Zemedikun, D., Wynne-Jones, G., Guariglia, A., Roberts, T., & Kigozi, J. (2021). Methodological considerations in the assessment of direct and indirect costs of back pain: A systematic scoping review. PloS one, e0251406 - e0251406. https://doi.org/10.1371/journal.pone.0251406

Background Back pain is a common and costly health problem worldwide. There is yet a lack of consistent methodologies to estimate the economic burden of back pain to society. Objective To systematically evaluate the methodologies used in the publishe... Read More about Methodological considerations in the assessment of direct and indirect costs of back pain: A systematic scoping review.

Clinical Outcomes of Proximal Optimization Technique (POT) in Bifurcation Stenting Short title: Impact of proximal optimization technique (2021)
Journal Article
Mamas, Rashid, & Rashid. (2021). Clinical Outcomes of Proximal Optimization Technique (POT) in Bifurcation Stenting Short title: Impact of proximal optimization technique. EuroIntervention, https://doi.org/10.4244/EIJ-D-20-01393

Background: Optimal deployment of coronary stents in a bifurcation lesion remains a matter of debate.

Aims: We sought to capture the daily practice of bifurcation stenting by means of a worldwide registry and to investigate how the post-implantati... Read More about Clinical Outcomes of Proximal Optimization Technique (POT) in Bifurcation Stenting Short title: Impact of proximal optimization technique.

“Pacing does help you get your life back”: The acceptability of a newly developed activity pacing framework for chronic pain/fatigue (2021)
Journal Article
Antcliff, D., Keenan, A., Woby, S., Keeley, P., & McGowan, L. (2021). “Pacing does help you get your life back”: The acceptability of a newly developed activity pacing framework for chronic pain/fatigue. Musculoskeletal Care, 20(1), 99-110. https://doi.org/10.1002/msc.1557

Objectives
We have developed and feasibility tested an activity pacing framework for clinicians to standardise their recommendations of activity pacing to patients with chronic pain/fatigue. This study aimed to explore the acceptability and fidelity... Read More about “Pacing does help you get your life back”: The acceptability of a newly developed activity pacing framework for chronic pain/fatigue.

When the World Throws You a Curve Ball: Lessons Learned in Breast Cancer Management (2021)
Journal Article
Obeng-Gyasi, S., Coles, C. E., Jones, J., Sacks, R., Lightowlers, S., Bliss, J. M., …Kalinsky, K. (2021). When the World Throws You a Curve Ball: Lessons Learned in Breast Cancer Management. American Society of Clinical Oncology educational book, 41(41), e79-e89. https://doi.org/10.1200/edbk_320691

In the care of patients with operable breast cancer, there has been a shift toward increasing use of neoadjuvant therapy. There are benefits to neoadjuvant therapy, such as monitoring for response, as well as an increased rate of breast conservation... Read More about When the World Throws You a Curve Ball: Lessons Learned in Breast Cancer Management.

Prognostic models for predicting relapse or recurrence of major depressive disorder in adults (2021)
Journal Article
Moriarty, A. S., Meader, N., Snell, K. I., Riley, R. D., Paton, L. W., Chew-Graham, C. A., …McMillan, D. (2021). Prognostic models for predicting relapse or recurrence of major depressive disorder in adults. Cochrane Database of Systematic Reviews, 2021(5), Article ARTN CD013491. https://doi.org/10.1002/14651858.cd013491.pub2

BACKGROUND: Relapse (the re-emergence of depressive symptoms after some level of improvement but preceding recovery) and recurrence (onset of a new depressive episode after recovery) are common in depression, lead to worse outcomes and quality of lif... Read More about Prognostic models for predicting relapse or recurrence of major depressive disorder in adults.

Developing more generalizable prediction models from pooled studies and large clustered data sets (2021)
Journal Article
de Jong, V. M. T., Moons, K. G. M., Eijkemans, M. J. C., Riley, R. D., & Debray, T. P. A. (2021). Developing more generalizable prediction models from pooled studies and large clustered data sets. Statistics in Medicine, 40(15), 3533-3559. https://doi.org/10.1002/sim.8981

Prediction models often yield inaccurate predictions for new individuals. Large data sets from pooled studies or electronic healthcare records may alleviate this with an increased sample size and variability in sample characteristics. However, existi... Read More about Developing more generalizable prediction models from pooled studies and large clustered data sets.

Experiences of general practice care for self-harm: a qualitative study of young people's perspectives. (2021)
Journal Article
Dikomitis, L., Babatunde, O., Chew-Graham, C., & Mughal, F. (2021). Experiences of general practice care for self-harm: a qualitative study of young people's perspectives. British Journal of General Practice (BJGP), E744-E752. https://doi.org/10.3399/BJGP.2021.0091

BACKGROUND: Self-harm is a growing concern and rates of self-harm in young people presenting to general practice are rising. There is however an absence of evidence on young people's experiences of GP care and on accessing general practice. AIM: To e... Read More about Experiences of general practice care for self-harm: a qualitative study of young people's perspectives..

'There's the end of an auld sang': Farewell to the NHS market. (2021)
Journal Article
Paton, C. (2021). 'There's the end of an auld sang': Farewell to the NHS market. International Journal of Health Planning and Management, 36(5), 1392-1396. https://doi.org/10.1002/hpm.3173

The new White Paper, Integration and Innovation, prefiguring a Health and Social Care Bill for England, means that the NHS structure in England will have come full circle in the last 32 years, since the Thatcher government began in 1989 to implement... Read More about 'There's the end of an auld sang': Farewell to the NHS market..

Temporal trends in annual incidence rates for psychiatric disorders and self-harm among children and adolescents in the UK, 2003-2018. (2021)
Journal Article
Chew-Graham. (2021). Temporal trends in annual incidence rates for psychiatric disorders and self-harm among children and adolescents in the UK, 2003-2018. BMC Psychiatry, 229 - ?. https://doi.org/10.1186/s12888-021-03235-w

BACKGROUND: There has been growing concern in the UK over recent years that a perceived mental health crisis is affecting children and adolescents, although published epidemiological evidence is limited. METHODS: Two population-based UK primary care... Read More about Temporal trends in annual incidence rates for psychiatric disorders and self-harm among children and adolescents in the UK, 2003-2018..