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Physical activity and fasting glucose in adults with abnormal glucose metabolism: Findings from two independent cross-sectional studies in China (2021)
Journal Article
Lu, L., Chen, Y., Cai, Y., Chen, T., Huang, Y., Meng, H., & Yu, D. (2021). Physical activity and fasting glucose in adults with abnormal glucose metabolism: Findings from two independent cross-sectional studies in China. Obesity Research and Clinical Practice, 15(3), 216-220. https://doi.org/10.1016/j.orcp.2021.03.011

Background
Relationship between physical activity and fasting glucose in people with abnormal glucose metabolism is not well-known. This study was to investigate dose–response association between physical activity (PAT) and fasting glucose from two... Read More about Physical activity and fasting glucose in adults with abnormal glucose metabolism: Findings from two independent cross-sectional studies in China.

The use of plain radiography in diagnosing osteoarthritis: A systematic review and time trend analysis (2021)
Journal Article
Henry‐Blake, C., Marshall, M., Treadwell, K., Parmar, S., Higgs, J., Edwards, J. J., & Peat, G. (2021). The use of plain radiography in diagnosing osteoarthritis: A systematic review and time trend analysis. Musculoskeletal Care, 21(2), 462-477. https://doi.org/10.1002/msc.1718

BACKGROUND: Prehabilitation is thought to reduce post-operative respiratory complications by optimising fitness before surgery. This prospective, single-centre study aimed to establish the effect of pre-operative exercise on cardiorespiratory fitness... Read More about The use of plain radiography in diagnosing osteoarthritis: A systematic review and time trend analysis.

Hearing the unheard voice-puberty experiences of young Pakistani men: A qualitative study (2021)
Journal Article
Shivji. (2021). Hearing the unheard voice-puberty experiences of young Pakistani men: A qualitative study. Journal of Adolescence, 36 - 47. https://doi.org/10.1016/j.adolescence.2021.02.003

Introduction
Puberty experiences of male adolescents can have significant impacts on physical and psychological health outcomes. This qualitative study explored the puberty experiences of young males in Pakistan, as there are limited accounts of wha... Read More about Hearing the unheard voice-puberty experiences of young Pakistani men: A qualitative study.

Identifying predictors of ventral hernia recurrence: systematic review and meta-analysis (2021)
Journal Article
Parker, S. G., Mallett, S., Quinn, L., Wood, C. P. J., Boulton, R. W., Jamshaid, S., …Halligan, S. (2021). Identifying predictors of ventral hernia recurrence: systematic review and meta-analysis. BJS Open, 5(2), 1-9. https://doi.org/10.1093/bjsopen/zraa071

BACKGROUND: Ventra hernias are increasing in prevalence and many recur despite attempted repair. To date, much of the literature is underpowered and divergent. As a result there is limited high quality evidence to inform surgeons succinctly which per... Read More about Identifying predictors of ventral hernia recurrence: systematic review and meta-analysis.

Clinical and cost effectiveness of a corticosteroid injection versus exercise therapy for shoulder pain in general practice: protocol for a randomised controlled trial (SIX Study). (2021)
Journal Article
Van Der Windt. (2021). Clinical and cost effectiveness of a corticosteroid injection versus exercise therapy for shoulder pain in general practice: protocol for a randomised controlled trial (SIX Study). BMJ Open, e050101 - ?. https://doi.org/10.1136/bmjopen-2021-050101

INTRODUCTION: Shoulder pain is common and the prognosis is often unfavourable. Dutch guidelines on the treatment of shoulder pain in primary care recommend a corticosteroid injection or a referral to exercise therapy, if initial pain management fails... Read More about Clinical and cost effectiveness of a corticosteroid injection versus exercise therapy for shoulder pain in general practice: protocol for a randomised controlled trial (SIX Study)..

Developing a model Fracture Liaison Service consultation with patients, carers and clinicians: a Delphi survey to inform content of the iFraP complex consultation intervention. (2021)
Journal Article
Bullock, L., Crawford-Manning, F., Cottrell, E., Fleming, J., Leyland, S., Edwards, J., …Paskins, Z. (2021). Developing a model Fracture Liaison Service consultation with patients, carers and clinicians: a Delphi survey to inform content of the iFraP complex consultation intervention. Archives of Osteoporosis, 16, 1- 17. https://doi.org/10.1007/s11657-021-00913-w

Fracture Liaison Services are recommended to deliver best practice in secondary fracture prevention. This modified Delphi survey, as part of the iFraP (Improving uptake of Fracture Prevention drug Treatments) study, provides consensus regarding tasks... Read More about Developing a model Fracture Liaison Service consultation with patients, carers and clinicians: a Delphi survey to inform content of the iFraP complex consultation intervention..

Single-centre survey of parents regarding the hidden burden of paediatric flexible bronchoscopy. (2021)
Journal Article
Gilchrist. (2021). Single-centre survey of parents regarding the hidden burden of paediatric flexible bronchoscopy. BMJ Paediatrics Open, e000991 - ?. https://doi.org/10.1136/bmjpo-2020-000991

Although paediatric flexible bronchoscopy is safe with relatively few side effects, parents frequently report an associated burden. To assess this, we undertook 25 semi-structured interviews with the parents of children who had recently undergone thi... Read More about Single-centre survey of parents regarding the hidden burden of paediatric flexible bronchoscopy..

Comparative differences in musculoskeletal pain consultation and analgesic prescription for people with dementia: a UK-wide matched cohort study (2021)
Journal Article
Bullock, L., Bedson, J., Chen, Y., Chew-Graham, C. A., & Campbell, P. (2021). Comparative differences in musculoskeletal pain consultation and analgesic prescription for people with dementia: a UK-wide matched cohort study. PAIN, 162(10), 2613-2620. https://doi.org/10.1097/j.pain.0000000000002257

Painful musculoskeletal conditions are common in older adults; however, pain identification, assessment, and management are reported to be suboptimal for people with dementia. Adequate pain management is an integral aspect of care for people with dem... Read More about Comparative differences in musculoskeletal pain consultation and analgesic prescription for people with dementia: a UK-wide matched cohort study.

Patient experiences with physiotherapy for knee osteoarthritis in Australia—a qualitative study (2021)
Journal Article
Dziedzic. (2021). Patient experiences with physiotherapy for knee osteoarthritis in Australia—a qualitative study. BMJ Open, e043689 - e043689. https://doi.org/10.1136/bmjopen-2020-043689

Objective Physiotherapists commonly provide non-surgical care for people with knee osteoarthritis (OA). It is unknown if patients are receiving high-quality physiotherapy care for their knee OA. This study aimed to explore the experiences of people w... Read More about Patient experiences with physiotherapy for knee osteoarthritis in Australia—a qualitative study.

Increased co-expression of PSMA2 and GLP-1 receptor in cervical cancer models in type 2 diabetes attenuated by Exendin-4: A translational case-control study. (2021)
Journal Article
Kwong. (2021). Increased co-expression of PSMA2 and GLP-1 receptor in cervical cancer models in type 2 diabetes attenuated by Exendin-4: A translational case-control study. EBioMedicine, 1- 15. https://doi.org/10.1016/j.ebiom.2021.103242

BACKGROUND: Type 2 diabetes (T2D) increases the risk of many types of cancer. Dysregulation of proteasome-related protein degradation leads to tumorigenesis, while Exendin-4, a glucagon-like peptide 1 receptor (GLP-1R) agonist, possesses anti-cancer... Read More about Increased co-expression of PSMA2 and GLP-1 receptor in cervical cancer models in type 2 diabetes attenuated by Exendin-4: A translational case-control study..

Overuse injuries in runners of different abilities—a one-year prospective study (2021)
Journal Article
Winter, S. (2021). Overuse injuries in runners of different abilities—a one-year prospective study. Research in Sports Medicine, 196 - 212. https://doi.org/10.1080/15438627.2019.1616548

The aim of this prospective study was to investigate differences in participant characteristics, previous injury, running dynamics during a long-distance run, and training between injured and uninjured runners in runners of different abilities. Cente... Read More about Overuse injuries in runners of different abilities—a one-year prospective study.

Predicting negative health outcomes in older general practice patients with chronic illness: Rationale and development of the PROPERmed harmonized individual participant data database. (2021)
Journal Article
(2021). Predicting negative health outcomes in older general practice patients with chronic illness: Rationale and development of the PROPERmed harmonized individual participant data database. Mechanisms of Ageing and Development, https://doi.org/10.1016/j.mad.2021.111436

The prevalence of multimorbidity and polypharmacy increases significantly with age and are associated with negative health consequences. However, most current interventions to optimize medication have failed to show significant effects on patient-rel... Read More about Predicting negative health outcomes in older general practice patients with chronic illness: Rationale and development of the PROPERmed harmonized individual participant data database..

Use and evaluation of assistive technologies for upper limb function in tetraplegia (2021)
Journal Article
Readioff, R., Kamran Siddiqui, Z., Stewart, C., Fulbrook, L., O’Connor, R. J., & Chadwick, E. K. (2021). Use and evaluation of assistive technologies for upper limb function in tetraplegia. Journal of Spinal Cord Medicine, 45(6), 1 - 12. https://doi.org/10.1080/10790268.2021.1878342

Context More than half of all spinal cord injuries (SCI) occur at the cervical level leading to loss of upper limb function, restricted activity and reduced independence. Several technologies have been developed to assist with upper limb functions in... Read More about Use and evaluation of assistive technologies for upper limb function in tetraplegia.

External validation of clinical prediction models: simulation-based sample size calculations were more reliable than rules-of-thumb. (2021)
Journal Article
Snell, K. I., Archer, L., Ensor, J., Bonnett, L. J., Debray, T. P., Phillips, B., …Riley, R. D. (2021). External validation of clinical prediction models: simulation-based sample size calculations were more reliable than rules-of-thumb. Journal of Clinical Epidemiology, https://doi.org/10.1016/j.jclinepi.2021.02.011

INTRODUCTION: Sample size 'rules-of-thumb' for external validation of clinical prediction models suggest at least 100 events and 100 non-events. Such blanket guidance is imprecise, and not specific to the model or validation setting. We investigate f... Read More about External validation of clinical prediction models: simulation-based sample size calculations were more reliable than rules-of-thumb..

The influence of candidates' physical attributes on assessors' ratings in clinical practice (2021)
Journal Article
Sam, A., Reid, M., Thakerar, V., Gurnell, M., Westacott, R., Yeates, P., …Brown, C. (2021). The influence of candidates' physical attributes on assessors' ratings in clinical practice. Medical Teacher, 43(5), 554-559. https://doi.org/10.1080/0142159X.2021.1877268

BACKGROUND: Assessments of physician competence in the work-place are common and often contribute to high-stakes assessments. Previous research suggests that assessors' judgements can be influenced by candidates' physical attributes. We investigated... Read More about The influence of candidates' physical attributes on assessors' ratings in clinical practice.

Excess mortality in England and Wales during the first wave of the COVID-19 pandemic (2021)
Journal Article
Mamas. (2021). Excess mortality in England and Wales during the first wave of the COVID-19 pandemic. Journal of epidemiology and community health, 213-223. https://doi.org/10.1136/jech-2020-214764

Background Deaths during the COVID-19 pandemic result directly from infection and exacerbation of other diseases and indirectly from deferment of care for other conditions, and are socially and geographically patterned. We quantified excess mortality... Read More about Excess mortality in England and Wales during the first wave of the COVID-19 pandemic.

"People play it down and tell me it can't kill people, but I know people are dying each day". Children's health literacy relating to a global pandemic (COVID-19); an international cross sectional study. (2021)
Journal Article
Protheroe. (2021). "People play it down and tell me it can't kill people, but I know people are dying each day". Children's health literacy relating to a global pandemic (COVID-19); an international cross sectional study. PloS one, e0246405 - ?. https://doi.org/10.1371/journal.pone.0246405

The aim of this study was to examine aspects of children's health literacy; the information sources they were accessing, their information preferences, their perceived understanding of and their reported information needs in relation to COVID-19. An... Read More about "People play it down and tell me it can't kill people, but I know people are dying each day". Children's health literacy relating to a global pandemic (COVID-19); an international cross sectional study..

Effect of primary percutaneous coronary intervention on in-hospital outcomes among active cancer patients presenting with ST-elevation myocardial infarction: a propensity score matching analysis (2021)
Journal Article
Mamas. (2021). Effect of primary percutaneous coronary intervention on in-hospital outcomes among active cancer patients presenting with ST-elevation myocardial infarction: a propensity score matching analysis. European Heart Journal: Acute Cardiovascular Care, 829-839. https://doi.org/10.1093/ehjacc/zuaa032

Aims
Primary percutaneous coronary intervention (pPCI) is the gold standard, guideline-recommended revascularization strategy in patients presenting with ST-elevation myocardial infarction (STEMI). However, there are limited data on its use and effe... Read More about Effect of primary percutaneous coronary intervention on in-hospital outcomes among active cancer patients presenting with ST-elevation myocardial infarction: a propensity score matching analysis.

Incidence and Predictors of Postoperative Ischemic Stroke after Coronary Artery Bypass Grafting (2021)
Journal Article
Mamas. (2021). Incidence and Predictors of Postoperative Ischemic Stroke after Coronary Artery Bypass Grafting. International Journal of Clinical Practice, https://doi.org/10.1111/ijcp.14067

Background: Data on the incidence and outcomes of ischemic stroke in patients undergoing coronary artery bypass grafting (CABG) in the current era is limited. The goal of this study was to examine contemporary trends, predictors, and outcomes of isch... Read More about Incidence and Predictors of Postoperative Ischemic Stroke after Coronary Artery Bypass Grafting.