Recommended and observed statin use among US adults with and without cancer. (2024)
Journal Article
Kobo, O., Michos, E. D., Roguin, A., Bagur, R., Gulati, M., & Mamas, M. A. (in press). Recommended and observed statin use among US adults with and without cancer. European Journal of Preventive Cardiology, Article zwae057. https://doi.org/10.1093/eurjpc/zwae057

Patients with cancer are at increased cardiovascular risk. We aimed to compare the recommended and observed statin use among individuals with and without cancer. Using three 2-year cycles from the National Health and Nutrition Examination Survey [NHA... Read More about Recommended and observed statin use among US adults with and without cancer..

Trends in Cardiovascular Mortality Among Patients With Alzheimer's Disease in the United States from 1999 to 2020 (2024)
Journal Article
Ranganathan, S., Abramov, D., Chew, N. W., Mallen, C., Marshall, M., Kobo, O., & Mamas, M. A. (2024). Trends in Cardiovascular Mortality Among Patients With Alzheimer's Disease in the United States from 1999 to 2020. The American Journal of Cardiology, 211, 326-333. https://doi.org/10.1016/j.amjcard.2023.11.044

The clinical characteristics, managements, and outcomes of acute myocardial infarction in osteoarthritis patients; a cross-sectional analysis of 6.5 million patients. (2024)
Journal Article
Parmar, S. S., Mohamed, M. O., Mamas, M. A., & Wilkie, R. (in press). The clinical characteristics, managements, and outcomes of acute myocardial infarction in osteoarthritis patients; a cross-sectional analysis of 6.5 million patients. Expert Review of Cardiovascular Therapy, 22(1-3), 1-9. https://doi.org/10.1080/14779072.2024.2311696

The prevalence of osteoarthritis (OA) and cardiovascular disease are increasing and both conditions share similar risk factors. We investigated the association between OA and receipt of invasive managements and clinical outcomes in patients with acut... Read More about The clinical characteristics, managements, and outcomes of acute myocardial infarction in osteoarthritis patients; a cross-sectional analysis of 6.5 million patients..

The invasive investigation of INOCA in the coronary catheterization lab (2024)
Journal Article
Burgess, S. N., & Mamas, M. A. (2024). The invasive investigation of INOCA in the coronary catheterization lab. American Heart Journal Plus: Cardiology Research and Practice, 38, Article 100365. https://doi.org/10.1016/j.ahjo.2024.100365

Over half of all patients with angina have no angiographically demonstratable obstructive coronary disease, with a significant proportion of these patients having undiagnosed microvascular dysfunction and/or vasospastic angina. In chronic coronary sy... Read More about The invasive investigation of INOCA in the coronary catheterization lab.

Heart Failure Readmission in Patients With ST-Segment Elevation Myocardial Infarction and Active Cancer (2024)
Journal Article
Dafaalla, M., Abramov, D., Van Spall, H. G., Ghosh, A. K., Gale, C. P., Zaman, S., …Mamas, M. A. (in press). Heart Failure Readmission in Patients With ST-Segment Elevation Myocardial Infarction and Active Cancer. JACC: CardioOncology, 6(1), 117-129. https://doi.org/10.1016/j.jaccao.2023.10.011

Background
Although numerous studies have examined readmission with heart failure (HF) after acute myocardial infarction (AMI), limited data are available on HF readmission in cancer patients post-AMI.

Objectives
This study aimed... Read More about Heart Failure Readmission in Patients With ST-Segment Elevation Myocardial Infarction and Active Cancer.

Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors JACC State-of-the-Art Review (2023)
Journal Article
Figtree, G. A., Vernon, S. T., Harmer, J. A., Gray, M. P., Arnott, C., Bachour, E., …Nicholls, S. J. (in press). Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors JACC State-of-the-Art Review. Journal of the American College of Cardiology, 82(13), 1343-1359. https://doi.org/10.1016/j.jacc.2023.06.045

Reducing the incidence and prevalence of standard modifiable cardiovascular risk factors (SMuRFs) is critical to tackling the global burden of coronary artery disease (CAD). However, a substantial number of individuals develop coro... Read More about Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors JACC State-of-the-Art Review.

Rural and urban disparities in cardiovascular disease-related mortality in the USA over 20 years; have the trends been reversed by COVID-19? (2023)
Journal Article
Chaganty, S. S., Abramov, D., Van Spall, H. G. C., Bullock-Palmer, R. P., Vassiliou, V., Myint, P. K., …Mamas, M. A. (in press). Rural and urban disparities in cardiovascular disease-related mortality in the USA over 20 years; have the trends been reversed by COVID-19?. International Journal of Cardiology Cardiovascular Risk and Prevention, 19, Article 200202. https://doi.org/10.1016/j.ijcrp.2023.200202

Risk of Venous Thromboembolism With Gout Flares (2023)
Journal Article
Cipolletta, E., Tata, L. J., Nakafero, G., Avery, A. J., Mamas, M. A., & Abhishek, A. (2023). Risk of Venous Thromboembolism With Gout Flares. Arthritis and Rheumatology, 75(9), 1638-1647. https://doi.org/10.1002/art.42480

ObjectivePrevious studies demonstrated that the risk of venous thromboembolism (VTE) is increased in patients with gout, but not whether there was a temporal association between gout flare and VTE. This study was undertaken to evaluate potential temp... Read More about Risk of Venous Thromboembolism With Gout Flares.

What do we mean by complex percutaneous coronary intervention? An assessment of agreement amongst interventional cardiologists for defining complexity (2023)
Journal Article
Rjoob, K., McGilligan, V., McAllister, R., Bond, R., Doolub, G., Leslie, S. J., …Peace, A. (2023). What do we mean by complex percutaneous coronary intervention? An assessment of agreement amongst interventional cardiologists for defining complexity. Catheterization and Cardiovascular Interventions, 102(1), 1-10. https://doi.org/10.1002/ccd.30684

Racial Disparities in Mortality Associated With Acute Myocardial Infarction and COVID-19 in the United States: A Nationwide Analysis (2023)
Journal Article
Muhyieddeen, A., Cheng, S., Mamas, M. A., Beasley, D., Weins, G. C., & Gulati, M. (2023). Racial Disparities in Mortality Associated With Acute Myocardial Infarction and COVID-19 in the United States: A Nationwide Analysis. Current Problems in Cardiology, 48(9), Article 101798. https://doi.org/10.1016/j.cpcardiol.2023.101798

This study assessed the COVID-19 pan-demic's impact on racial disparities in acute myocar-dial infarction (AMI) management and outcomes. We reviewed AMI patient management and outcomes in the pandemic's initial nine months, comparing COVID-19 and non... Read More about Racial Disparities in Mortality Associated With Acute Myocardial Infarction and COVID-19 in the United States: A Nationwide Analysis.

Race and sex disparities in acute outcomes of patients with acute ischemic stroke and diabetes mellitus. A national inpatient sample study (2023)
Journal Article
Thuemmler, R. J., Pana, T. A., Mohamed, M. O., Poobalan, A., Mamas, M. A., & Myint, P. K. (2023). Race and sex disparities in acute outcomes of patients with acute ischemic stroke and diabetes mellitus. A national inpatient sample study. Clinical Neurology and Neurosurgery, 229, Article 107747. https://doi.org/10.1016/j.clineuro.2023.107747

Background:
Diabetes Mellitus (DM) disproportionately affects racial minority groups and is a well-established risk factor for ischemic stroke and worse stroke outcomes. Whether racial disparities exist in acute outcomes of patients presenting with... Read More about Race and sex disparities in acute outcomes of patients with acute ischemic stroke and diabetes mellitus. A national inpatient sample study.

Association of Frailty Status on the Causes and Outcomes of Patients Admitted With Cardiovascular Disease. (2023)
Journal Article
Sokhal, B., Matetić, A., Rashid, M., Protheroe, J., Partington, R., Mallen, C., & Mamas, M. (2023). Association of Frailty Status on the Causes and Outcomes of Patients Admitted With Cardiovascular Disease. American Journal of Cardiology, 7 - 15. https://doi.org/10.1016/j.amjcard.2022.12.029

Data are limited about the contemporary association between frailty and the causes and outcomes of patients admitted with cardiovascular diseases (CVD). Using the US National Inpatient Sample, CVD admissions of interest (acute myocardial infarction,... Read More about Association of Frailty Status on the Causes and Outcomes of Patients Admitted With Cardiovascular Disease..

Primary prevention of cardiovascular disease in women with a Mediterranean diet: systematic review and meta-analysis. (2023)
Journal Article
Mamas. (2023). Primary prevention of cardiovascular disease in women with a Mediterranean diet: systematic review and meta-analysis. Heart, https://doi.org/10.1136/heartjnl-2022-321930

BACKGROUND: Dietary modification is a cornerstone of cardiovascular disease (CVD) prevention. A Mediterranean diet has been associated with a lower risk of CVD but no systematic reviews have evaluated this relationship specifically in women. OBJECTIV... Read More about Primary prevention of cardiovascular disease in women with a Mediterranean diet: systematic review and meta-analysis..

Determining cardiovascular risk in patients with unattributed chest pain in UK primary care: an electronic health record study (2023)
Journal Article
Jordan, K. P., Rathod-Mistry, T., van der Windt, D. A., Bailey, J., Chen, Y., Clarson, L., …Mamas, M. A. (2023). Determining cardiovascular risk in patients with unattributed chest pain in UK primary care: an electronic health record study. European Journal of Preventive Cardiology, 30(11), 1151-1161. https://doi.org/10.1093/eurjpc/zwad055

BACKGROUND: Most adults presenting in primary care with chest pain symptoms will not receive a diagnosis ("unattributed" chest pain) but are at increased risk of cardiovascular events. AIM: To assess within patients with unattributed chest pain, risk... Read More about Determining cardiovascular risk in patients with unattributed chest pain in UK primary care: an electronic health record study.

Musculoskeletal pain and its impact on prognosis following acute coronary syndrome or stroke: A linked electronic health record cohort study (2023)
Journal Article
Mason, K. J., Jordan, K. P., Heron, N., Edwards, J. J., Bailey, J., Achana, F. A., …Marshall, M. (2023). Musculoskeletal pain and its impact on prognosis following acute coronary syndrome or stroke: A linked electronic health record cohort study. Musculoskeletal Care, 21(3), 749-762. https://doi.org/10.1002/msc.1748

OBJECTIVE: Musculoskeletal painful conditions are a risk factor for cardiovascular disease (CVD), but less is known about whether musculoskeletal pain also worsens prognosis from CVD. The objective was to determine whether patients with musculoskelet... Read More about Musculoskeletal pain and its impact on prognosis following acute coronary syndrome or stroke: A linked electronic health record cohort study.

Association of Depression and Poor Mental Health With Cardiovascular Disease and Suboptimal Cardiovascular Health Among Young Adults in the United States. (2023)
Journal Article
Mamas, M. A., Kwapong, Y. A., Boakye, E., Khan, S. S., Honigberg, M. C., Martin, S. S., …Sharma, G. (2023). Association of Depression and Poor Mental Health With Cardiovascular Disease and Suboptimal Cardiovascular Health Among Young Adults in the United States. Journal of the American Heart Association, 12(3), Article e028332. https://doi.org/10.1161/jaha.122.028332

Background Depression is a nontraditional risk factor for cardiovascular disease (CVD). Data on the association of depression and poor mental health with CVD and suboptimal cardiovascular health (CVH) among young adults are limited. Methods and Resul... Read More about Association of Depression and Poor Mental Health With Cardiovascular Disease and Suboptimal Cardiovascular Health Among Young Adults in the United States..

Sex-Specific Outcomes of Acute Stroke in Patients with Systemic Lupus Erythematosus: A National Inpatient Sample Study. (2023)
Journal Article
Carter, B., Jesenakova, S., Pana, T., Mohamed, M., Mamas, M., Myint, P., & Hollick, R. (2023). Sex-Specific Outcomes of Acute Stroke in Patients with Systemic Lupus Erythematosus: A National Inpatient Sample Study. Journal of Clinical Medicine, https://doi.org/10.3390/jcm12020462

Background: Systemic lupus erythematosus (SLE) is an autoimmune disorder associated with increased stroke risk. Its association with stroke outcomes remains poorly understood. In this study, we aimed to compare the sex-specific SLE-associated acute s... Read More about Sex-Specific Outcomes of Acute Stroke in Patients with Systemic Lupus Erythematosus: A National Inpatient Sample Study..

Temporal trends of hospitalizations, comorbidity burden and in-hospital outcomes in patients admitted with asthma in the United States: Population-based study. (2022)
Journal Article
Mamas. (2022). Temporal trends of hospitalizations, comorbidity burden and in-hospital outcomes in patients admitted with asthma in the United States: Population-based study. PloS one, e0276731 - ?. https://doi.org/10.1371/journal.pone.0276731

BACKGROUND: Asthma is a prevalent chronic respiratory condition and remains a common cause for hospitalization. However, contemporary data on asthma hospitalization rates, comorbidity burden, and in-hospital outcomes are lacking.

METHODS: Survey-... Read More about Temporal trends of hospitalizations, comorbidity burden and in-hospital outcomes in patients admitted with asthma in the United States: Population-based study..

Differential remodelling of mitochondrial subpopulations and mitochondrial dysfunction are a feature of early stage diabetes (2022)
Journal Article
Mamas. (2022). Differential remodelling of mitochondrial subpopulations and mitochondrial dysfunction are a feature of early stage diabetes. Scientific reports, https://doi.org/10.1038/s41598-022-04929-1

<jats:title>Abstract</jats:title><jats:p>Mitochondrial dysfunction is a feature of type I and type II diabetes, but there is a lack of consistency between reports and links to disease development. We aimed to investigate if mitochondrial structure–fu... Read More about Differential remodelling of mitochondrial subpopulations and mitochondrial dysfunction are a feature of early stage diabetes.

Effects of the COVID-19 pandemic on secondary care for cardiovascular disease in the UK: an electronic health record analysis across three countries. (2022)
Journal Article
Wright, F. L., Cheema, K., Goldacre, R., Hall, N., Herz, N., Islam, N., …Banerjee, A. (2023). Effects of the COVID-19 pandemic on secondary care for cardiovascular disease in the UK: an electronic health record analysis across three countries. European Heart Journal - Quality of Care and Clinical Outcomes, 9(4), 377-388. https://doi.org/10.1093/ehjqcco/qcac077

Background
Although morbidity and mortality from COVID-19 have been widely reported, the indirect effects of the pandemic beyond 2020 on other major diseases and health service activity have not been well described.

Methods and results
Analyses... Read More about Effects of the COVID-19 pandemic on secondary care for cardiovascular disease in the UK: an electronic health record analysis across three countries..