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Cost-effectiveness of a model consultation to support self-management in patients with osteoarthritis (2018)
Journal Article
Oppong, R., Jowett, S., Lewis, M., Clarkson, K., Paskins, Z., Croft, P., …Dziedzic, K. (2018). Cost-effectiveness of a model consultation to support self-management in patients with osteoarthritis. Rheumatology, 57(6), 1056-1063. https://doi.org/10.1093/rheumatology/key037

Objectives: The aim of this study was to estimate the cost-effectiveness of a model OA consultation for OA to support self-management compared with usual care. Methods: An incremental cost-utility analysis using patient responses to the three-level E... Read More about Cost-effectiveness of a model consultation to support self-management in patients with osteoarthritis.

Core outcome measurement instruments for clinical trials in nonspecific low back pain. (2018)
Journal Article
(2018). Core outcome measurement instruments for clinical trials in nonspecific low back pain. PAIN, 481-495. https://doi.org/10.1097/j.pain.0000000000001117

To standardize outcome reporting in clinical trials of patients with nonspecific low back pain, an international multidisciplinary panel recommended physical functioning, pain intensity, and health-related quality of life (HRQoL) as core outcome doma... Read More about Core outcome measurement instruments for clinical trials in nonspecific low back pain..

Development and external validation of risk scores for cardiovascular hospitalisation and rehospitalisation in diabetes patients (2018)
Journal Article
Yu. (2018). Development and external validation of risk scores for cardiovascular hospitalisation and rehospitalisation in diabetes patients. The Journal of Clinical Endocrinology & Metabolism, 1122-1129. https://doi.org/10.1210/jc.2017-02293

Context: Cardiovascular disease (CVD) is a common and costly reason for hospitalization and rehospitalization among patients with type 2 diabetes.

Objective: This study aimed to develop and externally validate two risk- prediction models for cardi... Read More about Development and external validation of risk scores for cardiovascular hospitalisation and rehospitalisation in diabetes patients.

Interpreting intracorporeal landscapes: how patients visualize pathophysiology and utilize medical images in their understanding of chronic musculoskeletal illness (2018)
Journal Article
Moore, A. J., Richardson, J. C., Bernard, M., & Sim, J. (2019). Interpreting intracorporeal landscapes: how patients visualize pathophysiology and utilize medical images in their understanding of chronic musculoskeletal illness. Disability and Rehabilitation, 41(14), 1647 - 1654. https://doi.org/10.1080/09638288.2018.1443162

Medical science and other sources, such as the media, increasingly inform the general public's understanding of disease. There is often discordance between this understanding and the diagnostic interpretations of health care practitioners (HCPs). In... Read More about Interpreting intracorporeal landscapes: how patients visualize pathophysiology and utilize medical images in their understanding of chronic musculoskeletal illness.

Change in physical activity level and clinical outcomes in older adults with knee pain: a secondary analysis from a randomised controlled trial (2018)
Journal Article
Holden. (2018). Change in physical activity level and clinical outcomes in older adults with knee pain: a secondary analysis from a randomised controlled trial. BMC Musculoskeletal Disorders, https://doi.org/10.1186/s12891-018-1968-z

Background
Exercise interventions improve clinical outcomes of pain and function in adults with knee pain due to osteoarthritis and higher levels of physical activity are associated with lower severity of pain and higher levels of physical functioni... Read More about Change in physical activity level and clinical outcomes in older adults with knee pain: a secondary analysis from a randomised controlled trial.

Age-related differences in foot mobility in individuals with patellofemoral pain (2018)
Journal Article
(2018). Age-related differences in foot mobility in individuals with patellofemoral pain. Journal of Foot and Ankle Research, https://doi.org/10.1186/s13047-018-0249-2

Background
Age-related changes in midfoot mobility have the potential to influence success with foot orthoses intervention in people with patellofemoral pain (PFP). The aim of this study was to determine whether older people with PFP demonstrate les... Read More about Age-related differences in foot mobility in individuals with patellofemoral pain.

Retroperitoneal Hemorrhage After Percutaneous Coronary Intervention: Incidence, Determinants, and Outcomes as Recorded by the British Cardiovascular Intervention Society. (2018)
Journal Article
Kontopantelis, E., Kinnaird, T., Potts, J., Rashid, M., Shoaib, A., Nolan, J., …Cardiovascular Intervention Society (BCIS) and National, B. (2018). Retroperitoneal Hemorrhage After Percutaneous Coronary Intervention: Incidence, Determinants, and Outcomes as Recorded by the British Cardiovascular Intervention Society. Circulation: Cardiovascular Interventions, 11(2), Article e005866. https://doi.org/10.1161/CIRCINTERVENTIONS.117.005866

BACKGROUND: Retroperitoneal hemorrhage (RH) is a rare bleeding complication of percutaneous coronary intervention, which can result as a consequence of femoral access or can occur spontaneously. This study aims to evaluate temporal changes in RH, its... Read More about Retroperitoneal Hemorrhage After Percutaneous Coronary Intervention: Incidence, Determinants, and Outcomes as Recorded by the British Cardiovascular Intervention Society..

Epidemiology of paediatric presentations with musculoskeletal problems in primary care. (2018)
Journal Article
Protheroe, & Dunn. (2018). Epidemiology of paediatric presentations with musculoskeletal problems in primary care. BMC Musculoskeletal Disorders, 40 - ?. https://doi.org/10.1186/s12891-018-1952-7

BACKGROUND: Musculoskeletal disease is a common cause of morbidity, but there is a paucity of musculoskeletal research focusing on paediatric populations, particularly in primary care settings. In particular, there is limited information on populatio... Read More about Epidemiology of paediatric presentations with musculoskeletal problems in primary care..

Epidemiology of paediatric presentations with musculoskeletal problems in primary care (2018)
Journal Article
Protheroe. (2018). Epidemiology of paediatric presentations with musculoskeletal problems in primary care. BMC Musculoskeletal Disorders, https://doi.org/10.1186/s12891-018-1952-7

Background
Musculoskeletal disease is a common cause of morbidity, but there is a paucity of musculoskeletal research focusing on paediatric populations, particularly in primary care settings. In particular, there is limited information on populatio... Read More about Epidemiology of paediatric presentations with musculoskeletal problems in primary care.

Subacromial impingement syndrome - What does this mean to and for the patient? A qualitative study (2018)
Journal Article
(2018). Subacromial impingement syndrome - What does this mean to and for the patient? A qualitative study. Musculoskeletal Science and Practice, 24-28. https://doi.org/10.1016/j.msksp.2017.10.008

Background
Structured exercise has been reported as the current treatment of choice for patients diagnosed with subacromial impingement syndrome (SIS). However, it has been suggested that this diagnostic term and the language used to explain this co... Read More about Subacromial impingement syndrome - What does this mean to and for the patient? A qualitative study.

Development and validation of risk prediction models for cardiovascular mortality in Chinese people initialising peritoneal dialysis: a cohort study (2018)
Journal Article
Yu. (2018). Development and validation of risk prediction models for cardiovascular mortality in Chinese people initialising peritoneal dialysis: a cohort study. Scientific reports, https://doi.org/10.1038/s41598-018-20160-3

Cardiovascular disease is the leading cause of death among patients receiving peritoneal dialysis. We aimed to develop and validate a risk prediction model for cardiovascular death within 2 years after the initiation of peritoneal dialysis (PD). A co... Read More about Development and validation of risk prediction models for cardiovascular mortality in Chinese people initialising peritoneal dialysis: a cohort study.

Maternal genome-wide DNA methylation profiling in gestational diabetes shows distinctive disease-associated changes relative to matched healthy pregnancies (2018)
Journal Article
Wu, P., Farrell, W., Haworth, K., Emes, R., Kitchen, M., Glossop, J., …Fryer, A. (2018). Maternal genome-wide DNA methylation profiling in gestational diabetes shows distinctive disease-associated changes relative to matched healthy pregnancies. Epigenetics, 122-128. https://doi.org/10.1080/15592294.2016.1166321

Several recent reports have described associations between gestational diabetes (GDM) and changes to the epigenomic landscape where the DNA samples were derived from either cord or placental sources. We employed genome-wide 450K array analysis to det... Read More about Maternal genome-wide DNA methylation profiling in gestational diabetes shows distinctive disease-associated changes relative to matched healthy pregnancies.

Does vitamin D supplementation improve bone density in vitamin D-deficient children? Protocol for an individual patient data meta-analysis. (2018)
Journal Article
(2018). Does vitamin D supplementation improve bone density in vitamin D-deficient children? Protocol for an individual patient data meta-analysis. BMJ Open, e019584 - ?. https://doi.org/10.1136/bmjopen-2017-019584

INTRODUCTION: Our previous study-level (aggregate data) meta-analysis suggested that vitamin D supplements may be beneficial for bone density specifically in children with vitamin D deficiency. However, the misclassification of vitamin D status inher... Read More about Does vitamin D supplementation improve bone density in vitamin D-deficient children? Protocol for an individual patient data meta-analysis..

Trends in prescribing of non-steroidal anti-inflammatory drugs in patients with cardiovascular disease: influence of national guidelines in UK primary care (2018)
Journal Article
Chen, Y., Bedson, J., Hayward, R. A., & Jordan, K. P. (2018). Trends in prescribing of non-steroidal anti-inflammatory drugs in patients with cardiovascular disease: influence of national guidelines in UK primary care. Family Practice, 35(4), https://doi.org/10.1093/fampra/cmx142

Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat pain, but have potential side effects in patients with cardiovascular disease (CVD). Objectives: To determine trends in NSAIDs prescribing between 2002 and 2010 in... Read More about Trends in prescribing of non-steroidal anti-inflammatory drugs in patients with cardiovascular disease: influence of national guidelines in UK primary care.

The Colombo Twin and Singleton Follow-up Study: a population based twin study of psychiatric disorders and metabolic syndrome in Sri Lanka (2018)
Journal Article
(2018). The Colombo Twin and Singleton Follow-up Study: a population based twin study of psychiatric disorders and metabolic syndrome in Sri Lanka. BMC Public Health, 1-15. https://doi.org/10.1186/s12889-017-4992-2

BACKGROUND: The disease burden related to mental disorders and metabolic syndrome is growing in low-and middle-income countries (LMIC). The Colombo Twin and Singleton Study (COTASS) is a population-based sample of twins and singletons in Colombo, Sri... Read More about The Colombo Twin and Singleton Follow-up Study: a population based twin study of psychiatric disorders and metabolic syndrome in Sri Lanka.

Preterm Delivery and Future Risk of Maternal Cardiovascular Disease: A Systematic Review and Meta-Analysis (2018)
Journal Article
Chew-Graham, & Mamas. (2018). Preterm Delivery and Future Risk of Maternal Cardiovascular Disease: A Systematic Review and Meta-Analysis. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, https://doi.org/10.1161/JAHA.117.007809

Abstract Background - Preterm delivery (<37 weeks gestational age) affects 11% of all pregnancies, but data are conflicting whether preterm birth is associated with long-term adverse maternal cardiovascular outcomes. We aimed to systematically evalua...

Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study (2018)
Journal Article
Mallen, Roddy, Bucknall, Hider, Muller, Paskins, & Helliwell. (2018). Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study. BMC Medicine, https://doi.org/10.1186/s12916-017-0987-1

Background
Glucocorticoids are associated with increased fracture risk and are the mainstay of treatment in polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). However, fracture risk in these conditions has not been previously quantified. T... Read More about Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study.

Systematic review into factors associated with the recruitment crisis in psychiatry in the UK: students', trainees' and consultants' views. (2018)
Journal Article
Choudry, A., & Farooq, S. (2018). Systematic review into factors associated with the recruitment crisis in psychiatry in the UK: students', trainees' and consultants' views. BJPsych Bulletin, 345 - 352. https://doi.org/10.1192/pb.bp.116.055269

Aims and method To review the literature to examine the factors that may be affecting recruitment into psychiatry in the UK. We systematically searched four databases to identify studies from 1974 to 2016 and identified 27 papers that met the specifi... Read More about Systematic review into factors associated with the recruitment crisis in psychiatry in the UK: students', trainees' and consultants' views..