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The pathway to consultation for rheumatoid arthritis: exploring anticipated actions between the onset of symptoms and face-to-face encounter with a healthcare professional. (2017)
Journal Article
Mallen. (2017). The pathway to consultation for rheumatoid arthritis: exploring anticipated actions between the onset of symptoms and face-to-face encounter with a healthcare professional. BMC Musculoskeletal Disorders, 258 -?. https://doi.org/10.1186/s12891-017-1619-9

BACKGROUND: When people first experience symptoms of rheumatoid arthritis (RA) they often delay seeking medical attention resulting in delayed diagnosis and treatment. This research assesses behaviours people might engage in prior to, or instead of,... Read More about The pathway to consultation for rheumatoid arthritis: exploring anticipated actions between the onset of symptoms and face-to-face encounter with a healthcare professional..

Effect of a model consultation informed by guideline on recorded quality of care of osteoarthritis (MOSAICS): a cluster randomised controlled trial in primary care (2017)
Journal Article
Jordan, K., Edwards, J., Porcheret, M., Healey, E., Jinks, C., Bedson, J., …Dziedzic, K. (2017). Effect of a model consultation informed by guideline on recorded quality of care of osteoarthritis (MOSAICS): a cluster randomised controlled trial in primary care. Osteoarthritis and Cartilage, 25(10), 1588-1597. https://doi.org/10.1016/j.joca.2017.05.017

Objective
To determine the effect of a model osteoarthritis (OA) consultation (MOAC) informed by National Institute for Health and Care Excellence (NICE) recommendations compared with usual care on recorded quality of care of clinical OA in general... Read More about Effect of a model consultation informed by guideline on recorded quality of care of osteoarthritis (MOSAICS): a cluster randomised controlled trial in primary care.

Consultation patterns of children and adolescents with knee pain in UK general practice: analysis of medical records (2017)
Journal Article
Campbell, P., Protheroe, J., Rajani, A., Dunn, K., & Michaleff, Z. (2017). Consultation patterns of children and adolescents with knee pain in UK general practice: analysis of medical records. BMC Musculoskeletal Disorders, https://doi.org/10.1186/s12891-017-1586-1

Background
Knee problems are common in children and adolescents. Despite this, little is known about the epidemiology of knee problems in children and adolescents who consult in general practice. The aim of this study was to describe consultations b... Read More about Consultation patterns of children and adolescents with knee pain in UK general practice: analysis of medical records.

Measurement of troponin and natriuretic peptides shortly after admission in patients with heart failure-does it add useful prognostic information? An analysis of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Studies (VERITAS). (2017)
Journal Article
(2017). Measurement of troponin and natriuretic peptides shortly after admission in patients with heart failure-does it add useful prognostic information? An analysis of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Studies (VERITAS). European Journal of Heart Failure, 739 -747. https://doi.org/10.1002/ejhf.786

OBJECTIVE: Plasma concentrations of B-type natriuretic peptide (BNP) and troponin are often measured for diagnostic purposes when patients are admitted with heart failure, but their prognostic value when measured soon after admission is uncertain. We... Read More about Measurement of troponin and natriuretic peptides shortly after admission in patients with heart failure-does it add useful prognostic information? An analysis of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Studies (VERITAS)..

Chest pain and shortness of breath in cardiovascular disease: a prospective cohort study in UK primary care (2017)
Journal Article
Barnett, L. A., Prior, J. A., Kadam, U. T., & Jordan, K. P. (2017). Chest pain and shortness of breath in cardiovascular disease: a prospective cohort study in UK primary care. BMJ Open, 7(5), Article e015857. https://doi.org/10.1136/bmjopen-2017-015857

OBJECTIVE: To determine characteristics associated with monthly chest pain and shortness of breath (SoB) during activity in cardiovascular disease (CVD) and trajectories of these symptoms over 10 months. STUDY DESIGN AND SETTING: Baseline questionnai... Read More about Chest pain and shortness of breath in cardiovascular disease: a prospective cohort study in UK primary care.

Does metformin protect against osteoarthritis? An electronic health record cohort study (2017)
Journal Article
Barnett, L. A., Jordan, K. P., Edwards, J. J., & Van Der Windt, D. A. (2017). Does metformin protect against osteoarthritis? An electronic health record cohort study. Primary Health Care Research and Development, 623-628. https://doi.org/10.1017/s1463423617000287

Background
Obesity is a major risk factor for osteoarthritis (OA) whilst there is some evidence that diabetes also increases risk. Metformin is a common oral treatment for those with diabetes.

Objective
The aim is to investigate whether metformi... Read More about Does metformin protect against osteoarthritis? An electronic health record cohort study.

Affective concordance in couples: a cross-sectional analysis of depression and anxiety consultations within a population of 13,507 couples in primary care (2017)
Journal Article
Walker, J., Liddle, J., Jordan, K., & Campbell, P. (2017). Affective concordance in couples: a cross-sectional analysis of depression and anxiety consultations within a population of 13,507 couples in primary care. BMC Psychiatry, https://doi.org/10.1186/s12888-017-1354-7

Background
Depression and anxiety are common and have a significant impact on the individual and wider society. One theory proposed to explain a heightened risk for depression and anxiety is affective concordance in couples (e.g. influence of shared... Read More about Affective concordance in couples: a cross-sectional analysis of depression and anxiety consultations within a population of 13,507 couples in primary care.

Patient experiences, attitudes and expectations towards receiving information about anti-TNF medication: a quantitative study (2017)
Journal Article
(2017). Patient experiences, attitudes and expectations towards receiving information about anti-TNF medication: a quantitative study. Clinical Rheumatology, 2595-2600. https://doi.org/10.1007/s10067-017-3642-5

The objective of the study was to measure patient attitudes and experience of information received during drug counselling for rheumatoid arthritis (RA) medications. This is a cross-sectional UK postal questionnaire study. Three RA patient groups—dis... Read More about Patient experiences, attitudes and expectations towards receiving information about anti-TNF medication: a quantitative study.

Economic evaluation of strategies for restarting anticoagulation therapy with warfarin based on Venous Thromboembolism (VTE) risk after an index unprovoked VTE event (2017)
Journal Article
(2017). Economic evaluation of strategies for restarting anticoagulation therapy with warfarin based on Venous Thromboembolism (VTE) risk after an index unprovoked VTE event. Journal of Thrombosis and Haemostasis, 1591-1600. https://doi.org/10.1111/jth.13739

Background
Following at least 3 months of anticoagulation therapy after a first unprovoked venous thromboembolism (VTE), there is uncertainty about the duration of therapy. Further anticoagulation therapy reduces the risk of having a potentially fat... Read More about Economic evaluation of strategies for restarting anticoagulation therapy with warfarin based on Venous Thromboembolism (VTE) risk after an index unprovoked VTE event.

Des caractéristiques de la goutte associées à la dépression mais pas à l’anxiété en soins primaires : conclusions initiales d’une étude de cohorte prospective (2017)
Journal Article
Mallen, Prior, Roddy, & Muller. (2017). Des caractéristiques de la goutte associées à la dépression mais pas à l’anxiété en soins primaires : conclusions initiales d’une étude de cohorte prospective. Revue du Rhumatisme, 84(5), 423-429. https://doi.org/10.1016/j.rhum.2017.05.004

Objectifs
Déterminer la prévalence de l’anxiété et de la dépression dans le contexte de la goutte, examiner les liens entre certaines caractéristiques de la goutte et ces comorbidités et identifier le rôle de l’allopurinol dans ces relations.

Mét... Read More about Des caractéristiques de la goutte associées à la dépression mais pas à l’anxiété en soins primaires : conclusions initiales d’une étude de cohorte prospective.

Cost-effectiveness of surgical interventions for the management of osteoarthritis: a systematic review of the literature (2017)
Journal Article
(2017). Cost-effectiveness of surgical interventions for the management of osteoarthritis: a systematic review of the literature. BMC Musculoskeletal Disorders, https://doi.org/10.1186/s12891-017-1540-2

Background
The primary purpose of this study is to assess the existing evidence on the cost-effectiveness of surgical interventions for the management of knee and hip osteoarthritis by systematically reviewing published economic evaluation studies.... Read More about Cost-effectiveness of surgical interventions for the management of osteoarthritis: a systematic review of the literature.

Potential health impact and cost-effectiveness of drug therapy for prehypertension (2017)
Journal Article
Yu. (2017). Potential health impact and cost-effectiveness of drug therapy for prehypertension. International Journal of Cardiology, 403-408. https://doi.org/10.1016/j.ijcard.2017.05.003

Background
Studies have reported that pharmacologic interventions with candesartan or ramipril could reduce the risk of hypertension among prehypertensive subjects free of clinical cardiovascular disease (CVD), however, the cost-effectiveness and lo... Read More about Potential health impact and cost-effectiveness of drug therapy for prehypertension.

Association between pulmonary function and renal function: findings from China and Australia. (2017)
Journal Article
Yu. (2017). Association between pulmonary function and renal function: findings from China and Australia. BMC Nephrology, https://doi.org/10.1186/s12882-017-0565-y

Background
The relationship between obstructive lung function and impaired renal function is unclear. This study investigated the dose-response relationship between obstructive lung function and impaired renal function.

Methods
Two independent c... Read More about Association between pulmonary function and renal function: findings from China and Australia..

Public priorities for osteoporosis and fracture research: results from a general population survey (2017)
Journal Article
Paskins, Z., Jinks, C., Mahmood, W., Jayakumar, P., Sangan, C. B., Belcher, J., & Gwilym, S. (2017). Public priorities for osteoporosis and fracture research: results from a general population survey. Archives of Osteoporosis, 12(45), https://doi.org/10.1007/s11657-017-0340-5

This is the first national study of public and patient research priorities in osteoporosis and fracture. We have identified new research areas of importance to members of the public, particularly ‘access to information from health professionals’. The... Read More about Public priorities for osteoporosis and fracture research: results from a general population survey.

Shoe-stiffening inserts for first metatarsophalangeal joint osteoarthritis (the SIMPLE trial): study protocol for a randomised controlled trial (2017)
Journal Article
Roddy. (2017). Shoe-stiffening inserts for first metatarsophalangeal joint osteoarthritis (the SIMPLE trial): study protocol for a randomised controlled trial. Trials, 198 - ?. https://doi.org/10.1186/s13063-017-1936-1

BACKGROUND: This article describes the design of a parallel-group, participant- and assessor-blinded randomised controlled trial comparing the effectiveness of shoe-stiffening inserts versus sham shoe insert(s) for reducing pain associated with first... Read More about Shoe-stiffening inserts for first metatarsophalangeal joint osteoarthritis (the SIMPLE trial): study protocol for a randomised controlled trial.

The clinical and cost-effectiveness of stratified care for patients with sciatica: the SCOPiC randomised controlled trial protocol (ISRCTN75449581). (2017)
Journal Article
Foster, N. E., Konstantinou, K., Lewis, M., Ogollah, R., Dunn, K. M., van der Windt, D., …Hay, E. M. (2017). The clinical and cost-effectiveness of stratified care for patients with sciatica: the SCOPiC randomised controlled trial protocol (ISRCTN75449581). BMC Musculoskeletal Disorders, 18, Article 172. https://doi.org/10.1186/s12891-017-1513-5

BACKGROUND: Sciatica has a substantial impact on patients, and is associated with high healthcare and societal costs. Although there is variation in the clinical management of sciatica, the current model of care usually involves an initial period of... Read More about The clinical and cost-effectiveness of stratified care for patients with sciatica: the SCOPiC randomised controlled trial protocol (ISRCTN75449581)..

Rationale and design of BISTRO: a randomized controlled trial to determine whether bioimpedance spectroscopy-guided fluid management maintains residual kidney function in incident haemodialysis patients (2017)
Journal Article
Davie, S., Coyle, D., Dasgupta, I., Andronis, L., Farrington, K., Wilkie, M., …Caskey, F. (2017). Rationale and design of BISTRO: a randomized controlled trial to determine whether bioimpedance spectroscopy-guided fluid management maintains residual kidney function in incident haemodialysis patients. BMC Nephrology, 18, Article 138. https://doi.org/10.1186/s12882-017-0554-1

BACKGROUND: Preserved residual kidney function (RKF) and normal fluid status are associated with better patient outcomes in incident haemodialysis patients. The objective of this trial is to determine whether using bioimpedance technology in prescrib... Read More about Rationale and design of BISTRO: a randomized controlled trial to determine whether bioimpedance spectroscopy-guided fluid management maintains residual kidney function in incident haemodialysis patients.

The incidence of first stroke in pregnant and non-pregnant women of childbearing age: a population-based cohort study from England (2017)
Journal Article
(2017). The incidence of first stroke in pregnant and non-pregnant women of childbearing age: a population-based cohort study from England. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, https://doi.org/10.1161/JAHA.116.004601

Abstract Background: Pregnant women may have an increased risk of stroke compared to non-pregnant women of similar age, but the magnitude and the timing of such risk are unclear. We examined the risk of first stroke event in women of childbearing age... Read More about The incidence of first stroke in pregnant and non-pregnant women of childbearing age: a population-based cohort study from England.

'It seems like you're going around in circles': recurrent biographical disruption constructed through the past, present and anticipated future in the narratives of young adults with inflammatory bowel disease. (2017)
Journal Article
Saunders. (2017). 'It seems like you're going around in circles': recurrent biographical disruption constructed through the past, present and anticipated future in the narratives of young adults with inflammatory bowel disease. Sociology of Health and Illness, 39(5), 726 -740. https://doi.org/10.1111/1467-9566.12561

Biographical disruption and related concepts continue to be widely drawn upon in explaining how individuals experience chronic illness. Through in-depth examination of the narrative experiences of two young adults with inflammatory bowel disease (IBD... Read More about 'It seems like you're going around in circles': recurrent biographical disruption constructed through the past, present and anticipated future in the narratives of young adults with inflammatory bowel disease..