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International Foot and Ankle Osteoarthritis Consortium review and research agenda for diagnosis, epidemiology, burden, outcome assessment and treatments. (2022)
Journal Article
Osteoarthritis Consortium, I. F. A. A., Arnold, J., Bowen, C., Chapman, L., Gates, L., Golightly, Y., Halstead, J., Hannan, M., Menz, H., Munteanu, S., Paterson, K., Roddy, E., Siddle, H., & Thomas, M. (2022). International Foot and Ankle Osteoarthritis Consortium review and research agenda for diagnosis, epidemiology, burden, outcome assessment and treatments. Osteoarthritis and Cartilage, 30(7), 945-955. https://doi.org/10.1016/j.joca.2022.02.603

OBJECTIVE: To summarise the available evidence relating to the diagnosis, epidemiology, burden, outcome assessment and treatment of foot and ankle osteoarthritis (OA) and to develop an agenda to guide future research. METHOD: Members of the Internati... Read More about International Foot and Ankle Osteoarthritis Consortium review and research agenda for diagnosis, epidemiology, burden, outcome assessment and treatments..

Healthy working life expectancy at age 50 for people with and without osteoarthritis in local and national English populations (2022)
Journal Article
Lynch, M., Bucknall, M., Jagger, C., & Wilkie, R. (2022). Healthy working life expectancy at age 50 for people with and without osteoarthritis in local and national English populations. Scientific reports, 12(1), Article 2408. https://doi.org/10.1038/s41598-022-06490-3

Retirement ages are rising in many countries to offset the challenges of population ageing, but osteoarthritis is an age-associated disease that is becoming more prevalent and may limit capacity to work until older ages. We aimed to assess the impact... Read More about Healthy working life expectancy at age 50 for people with and without osteoarthritis in local and national English populations.

Stratifying workers on sick leave due to musculoskeletal pain: Translation, cross-cultural adaptation and construct validity of the Norwegian Keele STarT MSK tool (2022)
Journal Article
Dunn, K. M., Hill, J. C., Rysstad, T., Grotle, M., Aasdahl, L., Hill, J. C., Tingulstad, A., & Tveter, A. T. (2022). Stratifying workers on sick leave due to musculoskeletal pain: Translation, cross-cultural adaptation and construct validity of the Norwegian Keele STarT MSK tool. Scandinavian Journal of Pain, 22(2), 325-335. https://doi.org/10.1515/sjpain-2021-0144

Objectives Stratified care using prognostic models to estimate the risk profiles of patients has been increasing. A refined version of the popular STarT Back tool, the Keele STarT MSK tool, is a newly developed model for matched treatment across a wi... Read More about Stratifying workers on sick leave due to musculoskeletal pain: Translation, cross-cultural adaptation and construct validity of the Norwegian Keele STarT MSK tool.

Osteochondral Lesions of the Ankle Treated with Bone Marrow Concentrate with Hyaluronan and Fibrin: A Single-Centre Study (2022)
Journal Article
Abas, S., Kuiper, J. H., Roberts, S., McCarthy, H., Williams, M., Bing, A., Tins, B., & Makwana, N. (2022). Osteochondral Lesions of the Ankle Treated with Bone Marrow Concentrate with Hyaluronan and Fibrin: A Single-Centre Study. Cells, 11(4), Article 629. https://doi.org/10.3390/cells11040629

Osteochondral defects of the ankle (OCD) are being increasingly identified as a clinically significant consequence of injury to the ankle, with the potential to lead to osteoarthritis if left untreated. The aim of this retrospective cohort study was... Read More about Osteochondral Lesions of the Ankle Treated with Bone Marrow Concentrate with Hyaluronan and Fibrin: A Single-Centre Study.

Association Between Handover of Anesthesiology Care and 1-Year Mortality Among Adults Undergoing Cardiac Surgery (2022)
Journal Article
Mamas, M., Sun, L. Y., Jones, P. M., Wijeysundera, D. N., Mamas, M. A., Bader Eddeen, A., O'Connor, J., & O’Connor, J. (2022). Association Between Handover of Anesthesiology Care and 1-Year Mortality Among Adults Undergoing Cardiac Surgery. Jama Network Open, 5(2), Article ARTN e2148161. https://doi.org/10.1001/jamanetworkopen.2021.48161

Importance Handovers of anesthesia care from one anesthesiologist to another is an important intraoperative event. Despite its association with adverse events after noncardiac surgery, its impact in the context of cardiac surgery remains unclear.... Read More about Association Between Handover of Anesthesiology Care and 1-Year Mortality Among Adults Undergoing Cardiac Surgery.

Ethnic Differences in Cancer Rates Among Adults With Type 2 Diabetes in New Zealand From 1994 to 2018 (2022)
Journal Article
Yu, D., Wang, Z., Cai, Y., McBride, K., Osuagwu, U. L., Pickering, K., Baker, J., Cutfield, R., Orr-Walker, B. J., Sundborn, G., Jameson, M. B., Zhao, Z., & Simmons, D. (2022). Ethnic Differences in Cancer Rates Among Adults With Type 2 Diabetes in New Zealand From 1994 to 2018. Jama Network Open, 5(2), Article e2147171. https://doi.org/10.1001/jamanetworkopen.2021.47171

Importance People with type 2 diabetes have greater risk for some site-specific cancers, and risks of cancers differ among racial and ethnic groups in the general population of Aotearoa New Zealand. The extent of ethnic disparities in cancer risks a... Read More about Ethnic Differences in Cancer Rates Among Adults With Type 2 Diabetes in New Zealand From 1994 to 2018.

Development of radiographic classification criteria for hand osteoarthritis: a methodological report (Phase 2) (2022)
Journal Article
Haugen, I. K., Felson, D., Abhishek, A., Berenbaum, F., James Edwards, J., Herrero Beaumont, G., Hermann-Eriksen, M., Hill, C. L., Ishimori, M., Jonsson, H., Karjalainen, T., Ying Leung, Y., Maheu, E., Mallen, C. D., Helene Moe, R., Ramonda, R., Ritschl, V., Stamm, T. A., Szekanecz, Z., van der Giesen, F. J., …Kloppenburg, M. (2022). Development of radiographic classification criteria for hand osteoarthritis: a methodological report (Phase 2). RMD Open, 8(1), e002024 - e002024. https://doi.org/10.1136/rmdopen-2021-002024

Objectives In Phase 1 of developing new hand osteoarthritis (OA) classification criteria, features associated with hand OA were identified in a population with hand complaints. Radiographic findings could better discriminate patients with hand OA and... Read More about Development of radiographic classification criteria for hand osteoarthritis: a methodological report (Phase 2).

Clustering of comorbidities and associated outcomes in people with osteoarthritis - a UK Clinical Practice Research Datalink study. (2022)
Journal Article
Englund, M., Prieto-Alhambra, D., Zhang, W., Doherty, M., Swain, S., Coupland, C., Strauss, V., Mallen, C., Kuo, C., Sarmanova, A., & Bierma-Zeinstra, S. (2022). Clustering of comorbidities and associated outcomes in people with osteoarthritis - a UK Clinical Practice Research Datalink study. Osteoarthritis and Cartilage, https://doi.org/10.1016/j.joca.2021.12.013

OBJECTIVE: To examine the clusters of chronic conditions present in people with osteoarthritis and the associated risk factors and health outcomes. METHODS: Clinical Practice Research Datalink (CPRD) GOLD was used to identify people diagnosed with in... Read More about Clustering of comorbidities and associated outcomes in people with osteoarthritis - a UK Clinical Practice Research Datalink study..

Quality of acute myocardial infarction care in England and Wales during the COVID-19 pandemic: linked nationwide cohort study. (2022)
Journal Article
Aktaa, S., Yadegarfar, M. E., Wu, J., Rashid, M., de Belder, M., Deanfield, J., Schiele, F., Minchin, M., Mamas, M., & Gale, C. P. (2022). Quality of acute myocardial infarction care in England and Wales during the COVID-19 pandemic: linked nationwide cohort study. https://doi.org/10.1136/bmjqs-2021-013040

BACKGROUND AND OBJECTIVE: The impact of the COVID-19 pandemic on the quality of care for patients with acute myocardial infarction (AMI) is uncertain. We aimed to compare quality of AMI care in England and Wales during and before the COVID-19 pandemi... Read More about Quality of acute myocardial infarction care in England and Wales during the COVID-19 pandemic: linked nationwide cohort study..

Factors Associated with Healing Outcomes in Primary Care Patients with Diabetic Foot Ulcers: A Retrospective Study in a Multiethnic Sample (2022)
Journal Article
Bajpai, R., Zhu, X., Olsson, M. M., Goh, L. J., & Lim, V. H. (2022). Factors Associated with Healing Outcomes in Primary Care Patients with Diabetic Foot Ulcers: A Retrospective Study in a Multiethnic Sample. Advances in skin & wound care, 35(1), 22 - 29. https://doi.org/10.1097/01.ASW.0000801524.42349.4d

OBJECTIVE To identify and determine patient- and ulcer-related factors associated with healing outcomes within 3 months for patients with diabetic foot ulcer (DFU) in a multiethnic primary care sample. METHODS Retrospective data were collected over 3... Read More about Factors Associated with Healing Outcomes in Primary Care Patients with Diabetic Foot Ulcers: A Retrospective Study in a Multiethnic Sample.

Drivers and outcomes of variation in surgical versus transcatheter aortic valve replacement in Ontario, Canada: a population-based study. (2022)
Journal Article
Mamas. (2022). Drivers and outcomes of variation in surgical versus transcatheter aortic valve replacement in Ontario, Canada: a population-based study. Open Heart, https://doi.org/10.1136/openhrt-2021-001881

OBJECTIVES: To understand the patient and hospital level drivers of the variation in surgical versus trascatheter aortic valve replacement (SAVR vs TAVR) for patients with aortic stenosis (AS) and to explore whether this variation translates into dif... Read More about Drivers and outcomes of variation in surgical versus transcatheter aortic valve replacement in Ontario, Canada: a population-based study..

Primary Prevention of Cardiovascular and Heart Failure Events With SGLT2 Inhibitors, GLP-1 Receptor Agonists, and Their Combination in Type 2 Diabetes (2022)
Journal Article
Mamas. (2022). Primary Prevention of Cardiovascular and Heart Failure Events With SGLT2 Inhibitors, GLP-1 Receptor Agonists, and Their Combination in Type 2 Diabetes. Diabetes Care, 909-918. https://doi.org/10.2337/dc21-1113

OBJECTIVE
To assess associations between current use of sodium–glucose cotransporter 2 inhibitors (SGLT2is), glucagon-like peptide 1 receptor agonists (GLP-1RAs), and their combination and risk for major adverse cardiac and cerebrovascular events (M... Read More about Primary Prevention of Cardiovascular and Heart Failure Events With SGLT2 Inhibitors, GLP-1 Receptor Agonists, and Their Combination in Type 2 Diabetes.

Aluminium co-localises with Biondi ring tangles in Parkinson’s disease and epilepsy (2022)
Journal Article
(2022). Aluminium co-localises with Biondi ring tangles in Parkinson’s disease and epilepsy. Scientific reports, https://doi.org/10.1038/s41598-022-05627-8

Aluminium is known to accumulate in neuropathological hallmarks. However, such has only tentatively been suggested in Biondi ring tangles. Owing to their intracellular and filamentous structure rich in beta-pleated sheets, Biondi ring tangles might a... Read More about Aluminium co-localises with Biondi ring tangles in Parkinson’s disease and epilepsy.

Septal Flash as a Predictor of Cardiac Resynchronization Therapy Response: A Systematic Review and Meta-Analysis (2022)
Journal Article
(2022). Septal Flash as a Predictor of Cardiac Resynchronization Therapy Response: A Systematic Review and Meta-Analysis. Journal of Cardiovascular Echography, 198 - 198

Cardiac resynchronization therapy (CRT) in heart failure patients has been shown to improve patient outcomesin some but not all patients. A few studies have identified that septal flash on imaging is associated with response to CRT, but there has yet... Read More about Septal Flash as a Predictor of Cardiac Resynchronization Therapy Response: A Systematic Review and Meta-Analysis.

Patient and practitioner priorities and concerns about primary healthcare interactions for osteoarthritis: A meta-ethnography (2022)
Journal Article
Mallen, C., Vennik, J., Hughes, S., Smith, K. A., Misurya, P., Bostock, J., Howick, J., Little, P., Ratnapalan, M., Lyness, E., Dambha-Miller, H., Morrison, L., Leydon, G., Everitt, H., & Bishop, F. L. (2022). Patient and practitioner priorities and concerns about primary healthcare interactions for osteoarthritis: A meta-ethnography. Patient Education and Counseling, 105(7), 1865-1877. https://doi.org/10.1016/j.pec.2022.01.009

OBJECTIVE: To explore primary care practitioners' (PCPs) and patients' priorities and concerns for healthcare interactions for osteoarthritis (OA) in primary care. METHODS: We searched Embase, CINAHL, Medline, PsychInfo (1990 to present) for primary... Read More about Patient and practitioner priorities and concerns about primary healthcare interactions for osteoarthritis: A meta-ethnography.

A Rare Presentation of a Solitary Melanoma Bone Metastasis. (2022)
Journal Article
Cool. (2022). A Rare Presentation of a Solitary Melanoma Bone Metastasis. Cureus, e21479 - ?. https://doi.org/10.7759/cureus.21479

A 74-year-old woman presented with sudden onset pain and swelling in her right wrist. Plain radiographs showed a pathological fracture through a lytic lesion. The patient had a past medical history of melanoma on her right thigh, which had been excis... Read More about A Rare Presentation of a Solitary Melanoma Bone Metastasis..

Patient pathways in cardiology: Should pharmaceutical and medical device companies care? (2022)
Journal Article
Kwok, C. S., Muntean, E., Muntean, E., Foster, W., & Mallen, C. D. (2022). Patient pathways in cardiology: Should pharmaceutical and medical device companies care?. Critical Pathways in Cardiology: A Journal of Evidence-Based Medicine, 21(1), 57-60. https://doi.org/10.1097/HPC.0000000000000278

A shared goal of patients, providers and the companies that produce new therapies is to have these therapies used according to guidelines. Health services specialize in patient care and may lack the capabilities to take a product from conception thro... Read More about Patient pathways in cardiology: Should pharmaceutical and medical device companies care?.

Sex differences in high-risk but indicated coronary interventions (CHiP): National report from British Cardiovascular Intervention Society Registry. (2022)
Journal Article
Shamkhani, W., Kinnaird, T., Ludman, P., Rashid, M., & Mamas, M. A. (2022). Sex differences in high-risk but indicated coronary interventions (CHiP): National report from British Cardiovascular Intervention Society Registry. Catheterization and Cardiovascular Interventions, 99(2), 447-456. https://doi.org/10.1002/ccd.30081

OBJECTIVE: To assess sex-based differences in clinical outcomes following complex and high-risk but indicated percutaneous coronary intervention (CHiP). BACKGROUND: CHiP is increasingly common in contemporary percutaneous coronary intervention (PCI)... Read More about Sex differences in high-risk but indicated coronary interventions (CHiP): National report from British Cardiovascular Intervention Society Registry..

Subgroup effects of non-surgical and non-pharmacological treatment of patients with hand osteoarthritis: a protocol for an individual patient data meta-analysis. (2022)
Journal Article
Dziedzic, & Nicholls. (2022). Subgroup effects of non-surgical and non-pharmacological treatment of patients with hand osteoarthritis: a protocol for an individual patient data meta-analysis. BMJ Open, e057156 - ?. https://doi.org/10.1136/bmjopen-2021-057156

INTRODUCTION: Hand osteoarthritis (OA) is a common joint disorder in the adult population. No cure for hand OA is known yet, but treatment aims to reduce symptoms. Non-surgical and non-pharmacological therapy interventions can include splinting, pati... Read More about Subgroup effects of non-surgical and non-pharmacological treatment of patients with hand osteoarthritis: a protocol for an individual patient data meta-analysis..