Patient and practitioner priorities and concerns about primary healthcare interactions for osteoarthritis: A meta-ethnography (2022)
Journal Article
Mallen, C., Vennik, J., Hughes, S., Smith, K. A., Misurya, P., Bostock, J., …Bishop, F. L. (2022). Patient and practitioner priorities and concerns about primary healthcare interactions for osteoarthritis: A meta-ethnography. Patient Education and Counseling, 105(7), 1865-1877. https://doi.org/10.1016/j.pec.2022.01.009

OBJECTIVE: To explore primary care practitioners' (PCPs) and patients' priorities and concerns for healthcare interactions for osteoarthritis (OA) in primary care. METHODS: We searched Embase, CINAHL, Medline, PsychInfo (1990 to present) for primary... Read More about Patient and practitioner priorities and concerns about primary healthcare interactions for osteoarthritis: A meta-ethnography.

A Rare Presentation of a Solitary Melanoma Bone Metastasis. (2022)
Journal Article
Cool. (2022). A Rare Presentation of a Solitary Melanoma Bone Metastasis. Cureus, e21479 - ?. https://doi.org/10.7759/cureus.21479

A 74-year-old woman presented with sudden onset pain and swelling in her right wrist. Plain radiographs showed a pathological fracture through a lytic lesion. The patient had a past medical history of melanoma on her right thigh, which had been excis... Read More about A Rare Presentation of a Solitary Melanoma Bone Metastasis..

Patient pathways in cardiology: Should pharmaceutical and medical device companies care? (2022)
Journal Article
Kwok, C. S., Muntean, E., Muntean, E., Foster, W., & Mallen, C. D. (2022). Patient pathways in cardiology: Should pharmaceutical and medical device companies care?. Critical Pathways in Cardiology: A Journal of Evidence-Based Medicine, 21(1), 57-60. https://doi.org/10.1097/HPC.0000000000000278

A shared goal of patients, providers and the companies that produce new therapies is to have these therapies used according to guidelines. Health services specialize in patient care and may lack the capabilities to take a product from conception thro... Read More about Patient pathways in cardiology: Should pharmaceutical and medical device companies care?.

Sex differences in high-risk but indicated coronary interventions (CHiP): National report from British Cardiovascular Intervention Society Registry. (2022)
Journal Article
Shamkhani, W., Kinnaird, T., Ludman, P., Rashid, M., & Mamas, M. A. (2022). Sex differences in high-risk but indicated coronary interventions (CHiP): National report from British Cardiovascular Intervention Society Registry. Catheterization and Cardiovascular Interventions, 99(2), 447-456. https://doi.org/10.1002/ccd.30081

OBJECTIVE: To assess sex-based differences in clinical outcomes following complex and high-risk but indicated percutaneous coronary intervention (CHiP). BACKGROUND: CHiP is increasingly common in contemporary percutaneous coronary intervention (PCI)... Read More about Sex differences in high-risk but indicated coronary interventions (CHiP): National report from British Cardiovascular Intervention Society Registry..

Subgroup effects of non-surgical and non-pharmacological treatment of patients with hand osteoarthritis: a protocol for an individual patient data meta-analysis. (2022)
Journal Article
Dziedzic, & Nicholls. (2022). Subgroup effects of non-surgical and non-pharmacological treatment of patients with hand osteoarthritis: a protocol for an individual patient data meta-analysis. BMJ Open, e057156 - ?. https://doi.org/10.1136/bmjopen-2021-057156

INTRODUCTION: Hand osteoarthritis (OA) is a common joint disorder in the adult population. No cure for hand OA is known yet, but treatment aims to reduce symptoms. Non-surgical and non-pharmacological therapy interventions can include splinting, pati... Read More about Subgroup effects of non-surgical and non-pharmacological treatment of patients with hand osteoarthritis: a protocol for an individual patient data meta-analysis..

Trend, predictors, and outcomes of combined mitral valve replacement and coronary artery bypass graft in patients with concomitant mitral valve and coronary artery disease: a National Inpatient Sample database analysis (2022)
Journal Article
Ullah, W., Gul, S., Saleem, S., Syed, M. A., Khan, M. Z., Zahid, S., …Fischman, D. L. (2022). Trend, predictors, and outcomes of combined mitral valve replacement and coronary artery bypass graft in patients with concomitant mitral valve and coronary artery disease: a National Inpatient Sample database analysis. European Heart Journal Open, 2(1), Article oeac002. https://doi.org/10.1093/ehjopen/oeac002

Aims: Combined mitral valve replacement (MVR) and coronary artery bypass graft (CABG) procedures have been the norm for patients with concomitant mitral valve disease (MVD) and coronary artery disease (CAD) with no large-scale data on their safety an... Read More about Trend, predictors, and outcomes of combined mitral valve replacement and coronary artery bypass graft in patients with concomitant mitral valve and coronary artery disease: a National Inpatient Sample database analysis.

The adverse impact of COVID-19 pandemic on cardiovascular disease prevention and management in England, Scotland and Wales: A population-scale analysis of trends in medication data (2022)
Journal Article
Mamas. (2022). The adverse impact of COVID-19 pandemic on cardiovascular disease prevention and management in England, Scotland and Wales: A population-scale analysis of trends in medication data. MedRxiv, https://doi.org/10.1101/2021.12.31.21268587

<h4>Objectives</h4> To estimate the impact of the COVID-19 pandemic on cardiovascular disease (CVD) and CVD management using routinely collected medication data as a proxy. <h4>Design</h4> Descriptive and interrupted time series analysis using anonym... Read More about The adverse impact of COVID-19 pandemic on cardiovascular disease prevention and management in England, Scotland and Wales: A population-scale analysis of trends in medication data.

Substance use among pregnant women in the United States from 2004-2014: The National Inpatient Sample (2022)
Journal Article
Mamas, & Wu. (2022). Substance use among pregnant women in the United States from 2004-2014: The National Inpatient Sample. American Journal of Obstetrics and Gynecology, S339 - S339. https://doi.org/10.1016/j.ajog.2021.11.568

'Meeting Abstract'

Investigating the characteristics and functions of extracellular vesicles from umbilical cord mesenchymal stem cells (2021)
Thesis
Hyland, M. (2021). Investigating the characteristics and functions of extracellular vesicles from umbilical cord mesenchymal stem cells. (Thesis). Keele University

Rheumatoid Arthritis (RA) is a chronic autoimmune disease which is characterised by a loss of immune tolerance, and an infiltration of immune cells into joints causing inflammation. Current pharmaceutical treatments for RA have adverse side effects a... Read More about Investigating the characteristics and functions of extracellular vesicles from umbilical cord mesenchymal stem cells.

Clinical features presented to primary care prior to diagnosis of giant cell arteritis: an electronic health records study (2021)
Thesis
Barnett, L. A. (2021). Clinical features presented to primary care prior to diagnosis of giant cell arteritis: an electronic health records study. (Thesis). Keele University

Background: Giant cell arteritis (GCA) is the most common form of medium and large vessel vasculitis. This condition is associated with serious complications, such as blindness if left untreated, and is therefore considered a medical emergency. Howev... Read More about Clinical features presented to primary care prior to diagnosis of giant cell arteritis: an electronic health records study.

The development of individualised work absence prediction models in patients with neck and/or low back pain (2021)
Presentation / Conference
Wynne-Jones, G., Archer, L., Snell, K., Stynes, S., Dunn, K., Foster, N., …Hill, J. (2021, December). The development of individualised work absence prediction models in patients with neck and/or low back pain. Presented at Virtual Physiotherapy UK 2020 Conference

Implementation of a novel stratified PAthway of CarE for common musculoskeletal (MSK) conditions in primary care: protocol for a multicentre pragmatic randomised controlled trial (the PACE MSK trial) (2021)
Journal Article
(2021). Implementation of a novel stratified PAthway of CarE for common musculoskeletal (MSK) conditions in primary care: protocol for a multicentre pragmatic randomised controlled trial (the PACE MSK trial). BMJ Open, https://doi.org/10.1136/bmjopen-2021-057705

Introduction Musculoskeletal (MSK) conditions constitute the highest burden of disease globally, with healthcare services often utilised inappropriately and overburdened. The aim of this trial is to evaluate the effectiveness of a novel clinical PAth... Read More about Implementation of a novel stratified PAthway of CarE for common musculoskeletal (MSK) conditions in primary care: protocol for a multicentre pragmatic randomised controlled trial (the PACE MSK trial).

European Society for Radiotherapy and Oncology Advisory Committee in Radiation Oncology Practice consensus recommendations on patient selection and dose and fractionation for external beam radiotherapy in early breast cancer. (2021)
Journal Article
Meattini, I., Becherini, C., Boersma, L., Kaidar-Person, O., Nader Marta, G., Montero, A., …Coles, C. E. (2022). European Society for Radiotherapy and Oncology Advisory Committee in Radiation Oncology Practice consensus recommendations on patient selection and dose and fractionation for external beam radiotherapy in early breast cancer. Lancet Oncology, 23(1), e21 - e31. https://doi.org/10.1016/S1470-2045%2821%2900539-8

High-quality randomised clinical trials testing moderately fractionated breast radiotherapy have clearly shown that local control and survival is at least as effective as with 2 Gy daily fractions with similar or reduced normal tissue toxicity. Fewer... Read More about European Society for Radiotherapy and Oncology Advisory Committee in Radiation Oncology Practice consensus recommendations on patient selection and dose and fractionation for external beam radiotherapy in early breast cancer..

New developments in osteoarthritis pharmacological therapies. (2021)
Journal Article
(2021). New developments in osteoarthritis pharmacological therapies. Rheumatology, vi1 - vi11. https://doi.org/10.1093/rheumatology/keab679

OA is an increasingly common, painful condition with complex aetiology and limited therapies. Approaches to expanding our therapeutic armamentarium have included repurposing existing therapies used for other rheumatological conditions, modifying exis... Read More about New developments in osteoarthritis pharmacological therapies..

Development of an optimised physiotherapist-led treatment protocol for lateral elbow tendinopathy: a consensus study using an online nominal group technique (2021)
Journal Article
Bateman, M., Saunders, B., Littlewood, C., & Hill, J. (2021). Development of an optimised physiotherapist-led treatment protocol for lateral elbow tendinopathy: a consensus study using an online nominal group technique. BMJ Open, 11(12), Article e053841. https://doi.org/10.1136/bmjopen-2021-053841

OBJECTIVES: There are a wide range of physiotherapy treatment options for people with lateral elbow tendinopathy (LET); however, previous studies have reported inconsistent approaches to treatment and a lack of evidence demonstrating clinical effecti... Read More about Development of an optimised physiotherapist-led treatment protocol for lateral elbow tendinopathy: a consensus study using an online nominal group technique.

Therapeutic Effects of Hypoxic and Pro-Inflammatory Priming of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Inflammatory Arthritis (2021)
Journal Article
Kay, A. G., Roach, P., Morgan, R., Lodge, R., Hyland, M., Piccinini, A. M., …Treadwell, K. (2021). Therapeutic Effects of Hypoxic and Pro-Inflammatory Priming of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Inflammatory Arthritis. International Journal of Molecular Sciences, 23(1), 126 - 126. https://doi.org/10.3390/ijms23010126

<jats:p>Mesenchymal stem cells (MSCs) immunomodulate inflammatory responses through paracrine signalling, including via secretion of extracellular vesicles (EVs) in the cell secretome. We evaluated the therapeutic potential of MSCs-derived small EVs... Read More about Therapeutic Effects of Hypoxic and Pro-Inflammatory Priming of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Inflammatory Arthritis.

Decision making in percutaneous coronary intervention in patients with cancer: balancing ischaemic and bleeding risk. (2021)
Journal Article
Mamas. (2021). Decision making in percutaneous coronary intervention in patients with cancer: balancing ischaemic and bleeding risk. https://doi.org/10.1093/eurheartj/ehab403

Risk for Myocardial Infarction Following 5-Fluorouracil Treatment in Patients With Gastrointestinal Cancer: A Nationwide Registry-Based Study. (2021)
Journal Article
Mamas. (2021). Risk for Myocardial Infarction Following 5-Fluorouracil Treatment in Patients With Gastrointestinal Cancer: A Nationwide Registry-Based Study. https://doi.org/10.1016/j.jaccao.2021.11.001

Background: Myocardial infarction is a cardiac adverse event associated with 5-fluorouracil (5-FU). There are limited data on the incidence, risk, and prognosis of 5-FU-associated myocardial infarction. Objectives: The aim of this study was to examin... Read More about Risk for Myocardial Infarction Following 5-Fluorouracil Treatment in Patients With Gastrointestinal Cancer: A Nationwide Registry-Based Study..

Co-designing an Adaption of a Mobile App to Enhance Communication, Safety, and Well-being Among People Living at Home With Early-Stage Dementia: Protocol for an Exploratory Multiple Case Study (2021)
Journal Article
(2021). Co-designing an Adaption of a Mobile App to Enhance Communication, Safety, and Well-being Among People Living at Home With Early-Stage Dementia: Protocol for an Exploratory Multiple Case Study. JMIR Research Protocols, e19543 - e19543

<jats:sec> <jats:title>Background</jats:title> <jats:p>There is a growing interest in using mobile apps to support communication, safety, and well-being. Evidence directly from people with dementia regarding the usability, usefulness, and relevance o... Read More about Co-designing an Adaption of a Mobile App to Enhance Communication, Safety, and Well-being Among People Living at Home With Early-Stage Dementia: Protocol for an Exploratory Multiple Case Study.

Effects of an Online Education Program on Physical Therapists' Confidence in Weight Management for People With Osteoarthritis: A Randomized Controlled Trial (2021)
Journal Article
Allison, K., Jones, S., Hinman, R. S., Briggs, A. M., Sumithran, P., Quicke, J., …Bennell, K. (2021). Effects of an Online Education Program on Physical Therapists' Confidence in Weight Management for People With Osteoarthritis: A Randomized Controlled Trial. Arthritis Care and Research, 75(4), 835-847. https://doi.org/10.1002/acr.24828

OBJECTIVE: Evaluate effects of an online education program about weight management for osteoarthritis on physiotherapists' self-reported confidence in knowledge and skills in weight management, and attitudes toward obesity.

METHOD: A two-group ran... Read More about Effects of an Online Education Program on Physical Therapists' Confidence in Weight Management for People With Osteoarthritis: A Randomized Controlled Trial.