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Community Ageing Research 75+ (CARE75+) REMOTE study: a remote model of recruitment and assessment of the health, well-being and social circumstances of older people (2021)
Journal Article
Chew-Graham, C. (2021). Community Ageing Research 75+ (CARE75+) REMOTE study: a remote model of recruitment and assessment of the health, well-being and social circumstances of older people. BMJ Open, e048524 - e048524. https://doi.org/10.1136/bmjopen-2020-048524

<jats:sec><jats:title>Introduction</jats:title><jats:p>The Community Ageing Research 75+ (CARE75+) study is a longitudinal cohort study collecting extensive health and social data, with a focus on frailty, independence and quality of life in older ag... Read More about Community Ageing Research 75+ (CARE75+) REMOTE study: a remote model of recruitment and assessment of the health, well-being and social circumstances of older people.

Identifying Long-Term Trajectories of Foot Pain Severity and Potential Prognostic Factors: A Population-Based Cohort Study (2021)
Journal Article
Marshall, M., Bucknall, M., Rathod‐Mistry, T., Thomas, M. J., Edwards, J. J., Peat, G., Menz, H. B., & Roddy, E. (2023). Identifying Long-Term Trajectories of Foot Pain Severity and Potential Prognostic Factors: A Population-Based Cohort Study. Arthritis Care and Research, 75(5), 1123-1131. https://doi.org/10.1002/acr.24823

OBJECTIVES: To identify distinct foot pain trajectories over seven years and examine their associations with potential prognostic factors. METHODS: Adults aged =50?years registered with four general practices in North Staffordshire, UK were mailed a... Read More about Identifying Long-Term Trajectories of Foot Pain Severity and Potential Prognostic Factors: A Population-Based Cohort Study.

Understand the difference between clinical measured ultrafiltrationand real ultrafiltration in peritoneal dialysis. (2021)
Journal Article
Yu, Z., Wang, Z., Wang, Q., Zhang, M., Jin, H., Ding, L., Yan, H., Huang, J., Jin, Y., Davies, S., Fang, W., & Ni, Z. (2021). Understand the difference between clinical measured ultrafiltrationand real ultrafiltration in peritoneal dialysis. BMC Nephrology, 22, Article 382. https://doi.org/10.1186/s12882-021-02589-3

BACKGROUND: It has been noticed for years that ultrafiltration (UF) is important for survival in peritoneal dialysis. On the other hand, precise and convenient UF measurement suitable for patient daily practice is not as straight forward as it is to... Read More about Understand the difference between clinical measured ultrafiltrationand real ultrafiltration in peritoneal dialysis..

Aortic stenosis post-COVID-19: A mathematical model on waiting lists and mortality (2021)
Journal Article
Mamas. (2021). Aortic stenosis post-COVID-19: A mathematical model on waiting lists and mortality. MedRxiv, https://doi.org/10.1101/2021.11.11.21266212

<h4>Objectives</h4> To provide estimates for how different treatment pathways for the management of severe aortic stenosis (AS) may affect NHS England waiting list duration and associated mortality. <h4>Design</h4> We constructed a mathematical model... Read More about Aortic stenosis post-COVID-19: A mathematical model on waiting lists and mortality.

ASSOCIATIONS BETWEEN PARTIAL FOOT AMPUTATION LEVEL, GAIT PARAMETERS, AND MINIMUM IMPAIRMENT CRITERIA IN PARA-SPORT: A RESEARCH STUDY PROTOCOL (2021)
Journal Article
Lucas de Oliveira, F. C., Williamson, S., Ardern, C. L., Heron, N., Christa Janse van Rensburg, D., Jansen, M. G., O'Connor, S., Schoonmade, L., Thornton, J., & Pluim, B. M. (2021). ASSOCIATIONS BETWEEN PARTIAL FOOT AMPUTATION LEVEL, GAIT PARAMETERS, AND MINIMUM IMPAIRMENT CRITERIA IN PARA-SPORT: A RESEARCH STUDY PROTOCOL. Sports Medicine and Health Science, https://doi.org/10.1016/j.smhs.2021.11.001

Altered biomechanics due to amputation can contribute to substantial limitations, influencing sporting activities. Individuals with lower extremity amputations or congenital lower limb deficiency are encouraged to participate in para-sports. However,... Read More about ASSOCIATIONS BETWEEN PARTIAL FOOT AMPUTATION LEVEL, GAIT PARAMETERS, AND MINIMUM IMPAIRMENT CRITERIA IN PARA-SPORT: A RESEARCH STUDY PROTOCOL.

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference Contribution
Mallen, Mason, K., Frisher, Mamas, Jordan, Marshall, Heron, & White. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Presented at SAPC North 2021, Virtual

Background: There is evidence that painful musculoskeletal conditions are associated with increased risk of cardiovascular disease, but less is known about whether this impacts on prognosis of cardiovascular disease. The aim was to determine whether... Read More about Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM).

Choice and Outcomes of Left Main Coronary Disease Revascularization Strategies in England Before and After the COVID-19 Era (2021)
Journal Article
Mamas, & Rashid. (2021). Choice and Outcomes of Left Main Coronary Disease Revascularization Strategies in England Before and After the COVID-19 Era. Journal of the American College of Cardiology, B27 - B27. https://doi.org/10.1016/j.jacc.2021.09.916

Methods All patients with LM disease (= 50% stenosis) undergoing coronary revascularization in England between January 1, 2017 and August 19, 2020 were included (n = 22,235), stratified by time period (pre-COVID: January 1, 2017 to February 29, 2020;... Read More about Choice and Outcomes of Left Main Coronary Disease Revascularization Strategies in England Before and After the COVID-19 Era.

TCT-110 Fifteen-Year Trends in the Rates of Elective Percutaneous Coronary Intervention and Impact of COURAGE and ORBITA Trials: Insights From British Cardiovascular Intervention Society Dataset (2021)
Journal Article
Rashid, & Mamas. (2021). TCT-110 Fifteen-Year Trends in the Rates of Elective Percutaneous Coronary Intervention and Impact of COURAGE and ORBITA Trials: Insights From British Cardiovascular Intervention Society Dataset. Journal of the American College of Cardiology, B46 - B47. https://doi.org/10.1016/j.jacc.2021.09.960

Background This study was designed to evaluate temporal trends in elective rates of percutaneous coronary intervention (PCI) for stable angina and, specifically, to study the impact of the COURAGE and ORBITA trials on real-life practice. Methods We a... Read More about TCT-110 Fifteen-Year Trends in the Rates of Elective Percutaneous Coronary Intervention and Impact of COURAGE and ORBITA Trials: Insights From British Cardiovascular Intervention Society Dataset.

Treatment Effect of Primary Percutaneous Coronary Intervention on In-Hospital Outcomes of Active Cancer Patients Presenting With ST-Elevation Myocardial Infarction (2021)
Journal Article
Mamas. (2021). Treatment Effect of Primary Percutaneous Coronary Intervention on In-Hospital Outcomes of Active Cancer Patients Presenting With ST-Elevation Myocardial Infarction. Journal of the American College of Cardiology, B148 - B148

Background Primary percutaneous coronary intervention (pPCI) is the optimal strategy for coronary revascularization in patients presenting with ST-segment elevation myocardial infarction (STEMI). However, there are limited data on the utility of pPCI... Read More about Treatment Effect of Primary Percutaneous Coronary Intervention on In-Hospital Outcomes of Active Cancer Patients Presenting With ST-Elevation Myocardial Infarction.

Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: A CARE CR study. (2021)
Journal Article
Nichols, S., Engin, B., Carroll, S., Buckley, J., & Ingle, L. (2021). Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: A CARE CR study. Annals of Physical and Rehabilitation Medicine, 101462 - ?. https://doi.org/10.1016/j.rehab.2020.101462

BACKGROUND: Exercise prescription guidelines for individuals undergoing cardiovascular rehabilitation (CR) are often based on heart rate training zones and rating of perceived exertion (RPE). United Kingdom guidelines indicate that patients should ex... Read More about Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: A CARE CR study..

Case-finding and improving patient outcomes for chronic obstructive pulmonary disease in primary care: the BLISS research programme including cluster RCT (2021)
Journal Article
Adab, P., Jordan, R. E., Fitzmaurice, D., Ayres, J. G., Cheng, K., Cooper, B. G., Daley, A., Dickens, A., Enocson, A., Greenfield, S., Haroon, S., Jolly, K., Jowett, S., Lambe, T., Martin, J., Miller, M. R., Rai, K., Riley, R. D., Sadhra, S., Sitch, A., …Turner, A. (2021). Case-finding and improving patient outcomes for chronic obstructive pulmonary disease in primary care: the BLISS research programme including cluster RCT. Programme Grants for Applied Research, 9(13), 1 - 148. https://doi.org/10.3310/pgfar09130

BackgroundChronic obstructive pulmonary disease is a major contributor to morbidity, mortality and health service costs but is vastly underdiagnosed. Evidence on screening and how best to approach this is not clear. There are also uncertainties aroun... Read More about Case-finding and improving patient outcomes for chronic obstructive pulmonary disease in primary care: the BLISS research programme including cluster RCT.

Patient-related factors influencing management and procedural outcomes of de novo cardiac electronic device implantation (2021)
Thesis
Mohamed, M. O. A. H. Patient-related factors influencing management and procedural outcomes of de novo cardiac electronic device implantation. (Thesis). Keele University. https://keele-repository.worktribe.com/output/421280

Cardiac implantable electronic devices (CIED) are an essential part of the management of patients with life threatening arrhythmias. While many patient-related factors have been previously shown to play a role in the choice of CIED type offered to pa... Read More about Patient-related factors influencing management and procedural outcomes of de novo cardiac electronic device implantation.

Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic (2021)
Journal Article
Shoaib, A., Van Spall, H. G. C., Wu, J., Cleland, J. G. F., McDonagh, T. A., Rashid, M., Mohamed, M. O., Ahmed, F. Z., Deanfield, J., de Belder, M., Gale, C. P., & Mamas, M. A. (2021). Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic. European Heart Journal - Quality of Care and Clinical Outcomes, 7(4), 378-387. https://doi.org/10.1093/ehjqcco/qcab040

Aims We hypothesized that a decline in admissions with heart failure during COVID-19 pandemic would lead to a reciprocal rise in mortality for patients with heart failure in the community.

Methods and results We used National Heart Failure Audit d... Read More about Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic.

Patient satisfaction with the first contact physiotherapy service: Results from the national evaluation survey (2021)
Journal Article
Stynes, Wood, L., Bishop, A., & Goodwin, R. (2022). Patient satisfaction with the first contact physiotherapy service: Results from the national evaluation survey. Musculoskeletal Care, 20(2), 363-370. https://doi.org/10.1002/msc.1599

BACKGROUND: Musculoskeletal (MSK) First Contact Physiotherapists (FCPs) are diagnostic clinicians able to assess and manage undifferentiated and undiagnosed MSK presentations. The FCP role in primary care has been introduced to allow patients with MS... Read More about Patient satisfaction with the first contact physiotherapy service: Results from the national evaluation survey.

Impact of availability of catheter laboratory facilities on management and outcomes of acute myocardial infarction presenting with out of hospital cardiac arrest. (2021)
Journal Article
Mamas, M., & Rashid, M. (2021). Impact of availability of catheter laboratory facilities on management and outcomes of acute myocardial infarction presenting with out of hospital cardiac arrest. Resuscitation, 327-334. https://doi.org/10.1016/j.resuscitation.2021.10.031

OBJECTIVES: We aimed to identify whether the availability of catheter laboratory affects clinical outcomes of out-of-hospital cardiac arrest (OHCA) complicating myocardial infarction (AMI). METHODS: Patients admitted with a diagnosis of AMI and OHCA... Read More about Impact of availability of catheter laboratory facilities on management and outcomes of acute myocardial infarction presenting with out of hospital cardiac arrest..

Osteoarthritis year in review 2021: epidemiology & therapy (2021)
Journal Article
Quicke, J. G., Conaghan, P. G., Corp, N., & Peat, G. (2022). Osteoarthritis year in review 2021: epidemiology & therapy. Osteoarthritis and Cartilage, 30(2), 196-206. https://doi.org/10.1016/j.joca.2021.10.003

This "Year in review" presents a selection of research themes and individual studies from the clinical osteoarthritis (OA) field (epidemiology and therapy) and includes noteworthy descriptive, analytical-observational, and intervention studies. The e... Read More about Osteoarthritis year in review 2021: epidemiology & therapy.

What non-pharmacological treatments do people with polymyalgia rheumatica try: results from the PMR Cohort Study (2021)
Journal Article
Weddell, J., Hider, S., Mallen, C., & Muller, S. (2022). What non-pharmacological treatments do people with polymyalgia rheumatica try: results from the PMR Cohort Study. Rheumatology International, 285-290. https://doi.org/10.1007/s00296-021-05036-6

Polymyalgia rheumatica (PMR) is common. The mainstay of treatment, glucocorticoids, are associated with significant adverse effects and many patients remain on high doses for a number of years. Little is known about the use of other, non-pharmacologi... Read More about What non-pharmacological treatments do people with polymyalgia rheumatica try: results from the PMR Cohort Study.

AQP1 Promoter Variant, Water Transport, and Outcomes in Peritoneal Dialysis. (2021)
Journal Article
Morelle, J., Marechal, C., Yu, Z., Debaix, H., Corre, T., Lambie, M., Verduijn, M., Dekker, F., Bovy, P., Evenepoel, P., Bammens, B., Selgas, R., Bajo, M. A., Coester, A. M., Sow, A., Hautem, N., Struijk, D. G., Krediet, R. T., Balligand, J.-L., Goffin, E., …Devuyst, O. (2021). AQP1 Promoter Variant, Water Transport, and Outcomes in Peritoneal Dialysis. New England Journal of Medicine, 385, 1570 - 1580. https://doi.org/10.1056/NEJMoa2034279

BACKGROUND: Variability in ultrafiltration influences prescriptions and outcomes in patients with kidney failure who are treated with peritoneal dialysis. Variants in AQP1, the gene that encodes the archetypal water channel aquaporin-1, may contribut... Read More about AQP1 Promoter Variant, Water Transport, and Outcomes in Peritoneal Dialysis..

Outcomes of intravascular ultrasound versus optical coherence tomography guided percutaneous coronary angiography: A meta regression-based analysis. (2021)
Journal Article
Mamas, M. A., Sattar, Y., Abdul Razzack, A., Kompella, R., Alhajri, N., Arshad, J., Ullah, W., Zghouzi, M., Mir, T., Power, D., Qureshi, W. T., Aljaroudi, W., Elgendy, I. Y., & Alraies, M. C. (2022). Outcomes of intravascular ultrasound versus optical coherence tomography guided percutaneous coronary angiography: A meta regression-based analysis. Catheterization and Cardiovascular Interventions, 99(1), E1 - E11. https://doi.org/10.1002/ccd.29976

BACKGROUND: Studies comparing clinical outcomes with intravascular ultrasound (IVUS) versus optical coherence tomography (OCT) guidance for percutaneous coronary intervention (PCI) in patients presenting with coronary artery disease, including stable... Read More about Outcomes of intravascular ultrasound versus optical coherence tomography guided percutaneous coronary angiography: A meta regression-based analysis..

Examining the Trends in Online Health Information–Seeking Behavior About Chronic Obstructive Pulmonary Disease in Singapore: Analysis of Data From Google Trends and the Global Burden of Disease Study (2021)
Journal Article
Fang, Y., Shepherd, T. A., & E Smith, H. (2021). Examining the Trends in Online Health Information–Seeking Behavior About Chronic Obstructive Pulmonary Disease in Singapore: Analysis of Data From Google Trends and the Global Burden of Disease Study. Journal of Medical Internet Research, 23(10), https://doi.org/10.2196/19307

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death globally, and timely health care seeking is imperative for its prevention, early detection, and management. While online health information-seeking behavior... Read More about Examining the Trends in Online Health Information–Seeking Behavior About Chronic Obstructive Pulmonary Disease in Singapore: Analysis of Data From Google Trends and the Global Burden of Disease Study.