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Bempedoic acid and its role in contemporary management of hyperlipidemia in atherosclerosis. (2022)
Journal Article
Mamas. (2022). Bempedoic acid and its role in contemporary management of hyperlipidemia in atherosclerosis. https://doi.org/10.1080/07853890.2022.2059559

Atherosclerotic heart disease is the leading cause of mortality and morbidity in the USA. Low density lipoprotein (LDL) has been the target for many hypolipidemic agents to modify atherosclerotic risk. Bempedoic acid is a novel hypolipidemic drug tha... Read More about Bempedoic acid and its role in contemporary management of hyperlipidemia in atherosclerosis..

Relation of Extracardiac Vascular Disease and Outcomes in Patients With Diabetes (1.1 Million) Hospitalized for Acute Myocardial Infarction (2022)
Journal Article
Mamas. (2022). Relation of Extracardiac Vascular Disease and Outcomes in Patients With Diabetes (1.1 Million) Hospitalized for Acute Myocardial Infarction. American Journal of Cardiology, 8-18. https://doi.org/10.1016/j.amjcard.2022.04.005

The association between vascular disease and outcomes of patients with acute myocardial infarction (AMI) has not been well-defined in the diabetes mellitus (DM) population. All patients with DM presenting with AMI between October 2015 and December 20... Read More about Relation of Extracardiac Vascular Disease and Outcomes in Patients With Diabetes (1.1 Million) Hospitalized for Acute Myocardial Infarction.

Differential Impact of Type 1 and Type 2 Diabetes Mellitus on Outcomes Among 1.4 Million US Patients Undergoing Percutaneous Coronary Intervention. (2022)
Journal Article
Mamas. (2022). Differential Impact of Type 1 and Type 2 Diabetes Mellitus on Outcomes Among 1.4 Million US Patients Undergoing Percutaneous Coronary Intervention. https://doi.org/10.1016/j.carrev.2021.08.018

BACKGROUND: The aim was to determine the impact of diabetes mellitus (DM) on outcomes after percutaneous coronary intervention (PCI). There is limited data on the impact of DM and its subtypes among patients who underwent PCI during hospitalization.... Read More about Differential Impact of Type 1 and Type 2 Diabetes Mellitus on Outcomes Among 1.4 Million US Patients Undergoing Percutaneous Coronary Intervention..

P059 Acceptability of remote consulting during COVID-19 among patients with two common long-term musculoskeletal conditions: findings from three qualitative studies and recommendations for practice (2022)
Journal Article
Paskins, Z., Bullock, L., Manning, F., Bishop, S., Campbell, P., Cottrell, E., …Ryan, S. (2022). P059 Acceptability of remote consulting during COVID-19 among patients with two common long-term musculoskeletal conditions: findings from three qualitative studies and recommendations for practice. Rheumatology, 61(S1), https://doi.org/10.1093/rheumatology/keac133.058

<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background/Aims</jats:title> <jats:p>The COVID-19 pandemic led to the widespread adoption of remote consultations. Whilst remote consultations offer many potential advantages to patients and he... Read More about P059 Acceptability of remote consulting during COVID-19 among patients with two common long-term musculoskeletal conditions: findings from three qualitative studies and recommendations for practice.

P182 Health literacy and gout characteristics in a primary care cohort (2022)
Journal Article
Watson, L., Protheroe, J., Mallen, C., Muller, S., & Roddy, E. (2022). P182 Health literacy and gout characteristics in a primary care cohort. Rheumatology, 61(S1), https://doi.org/10.1093/rheumatology/keac133.181

<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background/Aims</jats:title> <jats:p>Gout is the most common inflammatory arthritis, affecting 2.5% of the UK population. It is often suboptimally managed, despite the availability of effective... Read More about P182 Health literacy and gout characteristics in a primary care cohort.

P091 Who do we risk leaving behind? A survey of digital access and e-health literacy in people with inflammatory conditions (2022)
Journal Article
Roddy, Paskins, Hider, & Muller. (2022). P091 Who do we risk leaving behind? A survey of digital access and e-health literacy in people with inflammatory conditions. Rheumatology, https://doi.org/10.1093/rheumatology/keac133.090

<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background/Aims</jats:title> <jats:p>The COVID-19 pandemic led to an overnight shift in healthcare delivery and rapid uptake of digital technology. Such approaches risk digital exclusion for pe... Read More about P091 Who do we risk leaving behind? A survey of digital access and e-health literacy in people with inflammatory conditions.

P137 Supporting patients to get the best from their osteoporosis treatment; what works for whom, why and in what circumstance: a rapid realist review (2022)
Journal Article
Paskins, Z., Babatunde, O., Sturrock, A., Toh, L., Horne, R., & Maidment, I. (2022). P137 Supporting patients to get the best from their osteoporosis treatment; what works for whom, why and in what circumstance: a rapid realist review. Rheumatology, https://doi.org/10.1093/rheumatology/keac133.136

<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background/Aims</jats:title> <jats:p>For two decades, clinicians and academics have been writing about the problem of poor adherence in osteoporosis, while people with osteoporosis have identif... Read More about P137 Supporting patients to get the best from their osteoporosis treatment; what works for whom, why and in what circumstance: a rapid realist review.

P008 Fracture liaison service management of patients aged 85 and older who sustain fragility fractures: audit and quality improvement (2022)
Journal Article
Paskins. (2022). P008 Fracture liaison service management of patients aged 85 and older who sustain fragility fractures: audit and quality improvement. Rheumatology, https://doi.org/10.1093/rheumatology/keac133.007

<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background/Aims</jats:title> <jats:p>Osteoporosis is a burdensome disease internationally, that is commonly diagnosed following fragility fracture. In line with national guidance, in 2018 the N... Read More about P008 Fracture liaison service management of patients aged 85 and older who sustain fragility fractures: audit and quality improvement.

Perceptual Disorders After Stroke: A Scoping Review of Interventions. (2022)
Journal Article
Hunter. (2022). Perceptual Disorders After Stroke: A Scoping Review of Interventions. Stroke, 1772 - 1787. https://doi.org/10.1161/STROKEAHA.121.035671

Perceptual disorders relating to hearing, smell, somatosensation, taste, touch, and vision commonly impair stroke survivors' ability to interpret sensory information, impacting on their ability to interact with the world. We aimed to identify and sum... Read More about Perceptual Disorders After Stroke: A Scoping Review of Interventions..

Temporal trends and patterns in atrial fibrillation incidence: a population-based study of 3·4 million individuals (2022)
Journal Article
Mamas. (2022). Temporal trends and patterns in atrial fibrillation incidence: a population-based study of 3·4 million individuals. The Lancet Regional Health Europe, https://doi.org/10.1016/j.lanepe.2022.100386

Background Population-based studies of atrial fibrillation (AF) incidence are needed to inform health-service planning, but evidence is conflicting. We assessed trends of AF incidence in a large general population cohort from England. Methods We used... Read More about Temporal trends and patterns in atrial fibrillation incidence: a population-based study of 3·4 million individuals.

Mirels’ score for upper limb metastatic lesions: do we need a different cutoff for recommending prophylactic fixation? (2022)
Journal Article
Hoban, K. A., Downie, S., Adamson, D. J., MacLean, J. G., Cool, P., & Jariwala, A. C. (2022). Mirels’ score for upper limb metastatic lesions: do we need a different cutoff for recommending prophylactic fixation?. https://doi.org/10.1016/j.jseint.2022.03.006

The aim of this study was to investigate the reproducibility, reliability and accuracy of Mirels’s score in upper limb bony metastatic disease and validate its use in predicting pathological fractures. Methods 45 patients with upper limb bony metasta... Read More about Mirels’ score for upper limb metastatic lesions: do we need a different cutoff for recommending prophylactic fixation?.

Treatment and Outcomes of Acute Myocardial Infarction in Patients With Polymyalgia Rheumatica With and Without Giant Cell Arteritis. (2022)
Journal Article
Sokhal, B., Matetić, A., Bharadwaj, A., Helliwell, T., Abhishek, A., Mallen, C., …Mamas, M. (2022). Treatment and Outcomes of Acute Myocardial Infarction in Patients With Polymyalgia Rheumatica With and Without Giant Cell Arteritis. American Journal of Cardiology, 12-19. https://doi.org/10.1016/j.amjcard.2022.03.034

This study analyzed the characteristics, management, and outcomes of patients with polymyalgia rheumatica (PMR) hospitalized with acute myocardial infarction (AMI), including sensitivity analysis for presence of giant cell arteritis (GCA). Using the... Read More about Treatment and Outcomes of Acute Myocardial Infarction in Patients With Polymyalgia Rheumatica With and Without Giant Cell Arteritis..

P181 Musculoskeletal pain and prognosis of acute coronary syndrome and cerebrovascular accident: a linked electronic health record cohort study (2022)
Journal Article
Mason, K. J., Jordan, K. P., Achana, F. A., Bailey, J., Chen, Y., Frisher, M., …Edwards, J. J. (2022). P181 Musculoskeletal pain and prognosis of acute coronary syndrome and cerebrovascular accident: a linked electronic health record cohort study. Rheumatology, 61(S1), https://doi.org/10.1093/rheumatology/keac133.180

<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background/Aims</jats:title> <jats:p>There is some evidence of an increased risk of cardiovascular disease in patients with painful musculoskeletal conditions, but it is unclear if musculoskele... Read More about P181 Musculoskeletal pain and prognosis of acute coronary syndrome and cerebrovascular accident: a linked electronic health record cohort study.

P183 Establishing the epidemiology of rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis in England using primary care electronic health record data (2022)
Journal Article
Scott, I. C., Whittle, R., Bailey, J., Twohig, H., Hider, S., Mallen, C., …Jordan, K. (2022). P183 Establishing the epidemiology of rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis in England using primary care electronic health record data. Rheumatology, 61(S1), https://doi.org/10.1093/rheumatology/keac133.182

<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background/Aims</jats:title> <jats:p>The substantial personal and socioeconomic costs associated with rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (SpA) mak... Read More about P183 Establishing the epidemiology of rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis in England using primary care electronic health record data.

Temporal trends in disease-specific causes of cardiovascular mortality amongst patients with cancer in the USA between 1999 and 2019 (2022)
Journal Article
Mamas. (2022). Temporal trends in disease-specific causes of cardiovascular mortality amongst patients with cancer in the USA between 1999 and 2019. European Heart Journal - Quality of Care and Clinical Outcomes, https://doi.org/10.1093/ehjqcco/qcac016

Aims: We report disease-specific cardiovascular causes of mortality among cancer patients in the USA between 1999 and 2019, considering temporal trends by age, sex, and cancer site.

Methods and results: We used the Multiple Cause of Death databas... Read More about Temporal trends in disease-specific causes of cardiovascular mortality amongst patients with cancer in the USA between 1999 and 2019.

In Vivo Antibacterial Efficacy of Antimicrobial Peptides Modified Metallic Implants-Systematic Review and Meta-Analysis. (2022)
Journal Article
Kaur Sandhu, A., Yang, Y., & Li, W. (2022). In Vivo Antibacterial Efficacy of Antimicrobial Peptides Modified Metallic Implants-Systematic Review and Meta-Analysis. ACS Biomaterials Science and Engineering, 1749-1762. https://doi.org/10.1021/acsbiomaterials.1c01307

Biomaterial-associated infection is difficult to detect and brings consequences that can lead to morbidity and mortality. Bacteria can adhere to the implant surface, grow, and form biofilms. Antimicrobial peptides (AMPs) can target and kill bacterial... Read More about In Vivo Antibacterial Efficacy of Antimicrobial Peptides Modified Metallic Implants-Systematic Review and Meta-Analysis..

Osteoarthritis Flares. (2022)
Journal Article
Thomas, M., Guillemin, F., & Neogi, T. (2022). Osteoarthritis Flares. Clinics in Geriatric Medicine, 38(2), 239 - 257. https://doi.org/10.1016/j.cger.2021.11.001

The phenomenon of flares is a common feature in the daily life of people with osteoarthritis (OA). Characterized by episodes of sudden-onset increases in signs and symptoms, their impact can often be distressing and disabling. Despite their potential... Read More about Osteoarthritis Flares..

Study protocol for the development and internal validation of SPIRIT (Schizophrenia Prediction of Resistance to Treatment): A clinical tool for predicting risk of treatment resistance to anti-psychotics in First Episode Schizophrenia (2022)
Journal Article
Farooq, S., Hattle, M., Dazzan, P., Kingstone, T., Ajnakina, O., Shiers, D., …Van Der Windt, D. (in press). Study protocol for the development and internal validation of SPIRIT (Schizophrenia Prediction of Resistance to Treatment): A clinical tool for predicting risk of treatment resistance to anti-psychotics in First Episode Schizophrenia. BMJ Open, 12(4), https://doi.org/10.1136/bmjopen-2021-056420

<jats:title>ABSTRACT</jats:title><jats:sec><jats:title>Introduction</jats:title><jats:p>Treatment Resistant Schizophrenia (TRS) is associated with significant impairment of functioning and high treatment costs. Identification of patients at high risk... Read More about Study protocol for the development and internal validation of SPIRIT (Schizophrenia Prediction of Resistance to Treatment): A clinical tool for predicting risk of treatment resistance to anti-psychotics in First Episode Schizophrenia.