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Symptom patterns and life with post-acute COVID-19 in children aged 8-17: a mixed methods studyprotocol. (2023)
Journal Article
Faux-Nightingale, A., Burton, C., Twohig, H., Bucknall, M., Carroll, W., Chew-Graham, C., …Welsh, V. (2023). Symptom patterns and life with post-acute COVID-19 in children aged 8-17: a mixed methods studyprotocol. British Journal of General Practice Open (BJGP Open), 7(2), Article BJGPO20220149. https://doi.org/10.3399/bjgpo.2022.0149

Background: While there is a substantial body of knowledge about acute COVID-19, less is known about long-COVID, where symptoms continue beyond 4 weeks.

Aim: To describe longer-term effects of COVID-19 infection in children and young people (CYP)... Read More about Symptom patterns and life with post-acute COVID-19 in children aged 8-17: a mixed methods studyprotocol..

Protocol for CLASSIC PBB: comparison of lower airway sampling strategies in children with protracted bacterial bronchitis (2022)
Journal Article
Gilchrist, F., Aspey, M., Bowler, R., Brodlie, M., Desai, S., Harris, C., …Carroll, W. D. (2022). Protocol for CLASSIC PBB: comparison of lower airway sampling strategies in children with protracted bacterial bronchitis. BMJ Paediatrics Open, e001722 - e001722. https://doi.org/10.1136/bmjpo-2022-001722

Background Protracted bacterial bronchitis (PBB) is an endobronchial infection and a the most common cause of chronic wet cough in young children. It is treated with antibiotics, which can only be targeted if the causative organism is known. As most... Read More about Protocol for CLASSIC PBB: comparison of lower airway sampling strategies in children with protracted bacterial bronchitis.

Why are children with asthma bullied? A risk factor analysis. (2021)
Journal Article
Gilchrist. (2021). Why are children with asthma bullied? A risk factor analysis. Archives of Disease in Childhood, https://doi.org/10.1136/archdischild-2021-321641

The links between bullying and asthma have not been explored in children. We wanted to determine the child/parent factors and attitudes associated with asthma-related bullying. Individual child/parent responses of children with asthma (N=943) from th... Read More about Why are children with asthma bullied? A risk factor analysis..

Managing chronic wet cough in children: another piece of the puzzle. (2021)
Journal Article
Gilchrist. (2021). Managing chronic wet cough in children: another piece of the puzzle. Lancet Respiratory Medicine, 1078 - 1079. https://doi.org/10.1016/S2213-2600%2821%2900159-4

Chronic wet cough is the hallmark of chronic obstructive pulmonary disease in older people and bronchiectasis in adults and older children. In young children, the commonest cause of chronic wet cough is protracted bacterial bronchitis (PBB) but there... Read More about Managing chronic wet cough in children: another piece of the puzzle..

Longitudinal assessment of lung clearance index to monitor disease progression in children and adults with cystic fibrosis. (2021)
Journal Article
Horsley, A. R., Belcher, J., Bayfield, K., Bianco, B., Cunningham, S., Fullwood, C., …Gilchrist, F. J. (2021). Longitudinal assessment of lung clearance index to monitor disease progression in children and adults with cystic fibrosis. Thorax, 77(4), https://doi.org/10.1136/thoraxjnl-2021-216928

BACKGROUND: Lung clearance index (LCI) is a valuable research tool in cystic fibrosis (CF) but clinical application has been limited by technical challenges and uncertainty about how to interpret longitudinal change. In order to help inform clinical... Read More about Longitudinal assessment of lung clearance index to monitor disease progression in children and adults with cystic fibrosis..

Why are children with asthma bullied? A quantitative analysis of bullying risk factors in the Room to Breathe cohort (2020)
Presentation / Conference
Gilchrist. (2020, September). Why are children with asthma bullied? A quantitative analysis of bullying risk factors in the Room to Breathe cohort. Presented at ERS International Congress 2020

Background: Bullying and asthma are common challenges faced by children worldwide. It has been shown that children with chronic health conditions are at higher risk of being bullied, but this has not been explored in detail in asthma. Aims and Object... Read More about Why are children with asthma bullied? A quantitative analysis of bullying risk factors in the Room to Breathe cohort.

Developing a core outcome set for children with protracted bacterial bronchitis. (2020)
Journal Article
Gilchrist. (2020). Developing a core outcome set for children with protracted bacterial bronchitis. ERJ Open Research, https://doi.org/10.1183/23120541.00344-2019

Background: Protracted bacterial bronchitis (PBB) is a chronic endobrochial infection and a leading cause of chronic wet cough in children. There is an urgent need for a randomised controlled trial to investigate the optimal treatment but there is no... Read More about Developing a core outcome set for children with protracted bacterial bronchitis..

Less sun, more cough: Annual hours of sunshine are inversely associated with hospital admissions for children with lower respiratory tract infection (2019)
Presentation / Conference
Gilchrist. (2019, September). Less sun, more cough: Annual hours of sunshine are inversely associated with hospital admissions for children with lower respiratory tract infection. Presented at ERS International Congress 2019, IFEMA, Madrid

Background: Vitamin D deficiency affects immune function increasing susceptibility to respiratory tract infections (RTI). Randomised controlled trials show vitamin D supplementation protects against acute RTIs. Most vitamin D (>90%) is acquired from... Read More about Less sun, more cough: Annual hours of sunshine are inversely associated with hospital admissions for children with lower respiratory tract infection.

UNWARRANTED USE OF NEPHROTOXIC ANTIBIOTICS IN CHILDREN WITH CYSTIC FIBROSIS (2018)
Presentation / Conference
Gilchrist. (2018, December). UNWARRANTED USE OF NEPHROTOXIC ANTIBIOTICS IN CHILDREN WITH CYSTIC FIBROSIS. Presented at British Thoracic Society Winter Meeting 2018, QEII Centre, Broad Sanctuary, Westminster, London, England

Introduction As life expectancy of individuals with cystic fibrosis (CF) continues to increase, complications resulting from lifetime drug exposures and CF comorbidities are becoming more prevalent. An example of this is chronic kidney disease (CKD).... Read More about UNWARRANTED USE OF NEPHROTOXIC ANTIBIOTICS IN CHILDREN WITH CYSTIC FIBROSIS.

Identifying Asthmatic Children using Tidal Breathing Parameters Measured by Structured Light Plethysmography (SLP) (2018)
Presentation / Conference
Gilchrist. (2018, September). Identifying Asthmatic Children using Tidal Breathing Parameters Measured by Structured Light Plethysmography (SLP). Presented at ERS International Congress 2018, Paris, France

Introduction: We have previously shown that several tidal breathing parameters measured using SLP varied between asthmatic children and healthy (Hmeidi et al., 2017). However, we did not test the classification power of a model which incorporates the... Read More about Identifying Asthmatic Children using Tidal Breathing Parameters Measured by Structured Light Plethysmography (SLP).

Is hypnotherapy an acceptable treatment option for children with habit cough? (2018)
Journal Article
Gilchrist, F. (2018). Is hypnotherapy an acceptable treatment option for children with habit cough?. Complementary Therapies in Medicine, 27 - 28. https://doi.org/10.1016/j.ctim.2018.01.005

Habit cough is a chronic, persistent dry cough which occurs in children only when awake. It is considered functional (non-organic) and can have a significant impact on the quality of life of the child and their family. One possible treatment option f... Read More about Is hypnotherapy an acceptable treatment option for children with habit cough?.

Chronic Cough In Children (2017)
Journal Article
Hine, C., Gilchrist, F., & Carroll, W. (2017). Chronic Cough In Children. Paediatrics and Child Health, 27(3), 121 - 127. https://doi.org/10.1016/j.paed.2017.02.001

All children cough. Despite the ubiquity of this common symptom, it remains a concern for many parents and results in a significant number of health consultations. Nearly every child in the UK will present to their family doctor with cough as the pre... Read More about Chronic Cough In Children.

Assessing chronic cough in children (2016)
Journal Article
Gilchrist. (2016). Assessing chronic cough in children. Paediatrics and Child Health, 273-275. https://doi.org/10.1016/j.paed.2016.03.002

Cough is a protective physiological reflex that aids the clearance of airway secretions and aspirated material. As such, it is normal to cough. Coughing becomes abnormal when the frequency or severity impacts on the child's ability to eat, sleep, pla... Read More about Assessing chronic cough in children.

A review of prednisolone prescribing for children with acute asthma in the UK (2016)
Journal Article
Gilchrist, F. J., Ahmad, A. N., Batchelor, H. K., Marriott, J. F., & Lenney, W. (2016). A review of prednisolone prescribing for children with acute asthma in the UK. Journal of Asthma, 53(6), 563 -566. https://doi.org/10.3109/02770903.2015.1118498

INTRODUCTION: Worldwide asthma guidelines recommend short courses of oral prednisolone in children with acute exacerbations generating high prescription numbers. There is a paucity of evidence to inform the optimal dose and course duration. This has... Read More about A review of prednisolone prescribing for children with acute asthma in the UK.

Research is the Future, the Future is……. (2015)
Journal Article
Gilchrist, F. J. (2015). Research is the Future, the Future is……. Paediatric Respiratory Reviews, 17, 32 - 33. https://doi.org/10.1016/j.prrv.2015.08.008

Over the past two decades, Professor Lenney has established the Paediatric Respiratory Department at the Royal Stoke University Hospital as a centre recognised for high quality research. A broad portfolio of clinical and laboratory based research is... Read More about Research is the Future, the Future is……..

Female sex is associated with increased risk of early readmission with asthma in Staffordshire children
Presentation / Conference
Gilchrist. Female sex is associated with increased risk of early readmission with asthma in Staffordshire children. Presented at ERS International Congress 2017

Background: Asthma is the commonest medical reason for a child to be admitted to hospital in the UK. c.15% are readmitted within 3 months.

Aim: We undertook a retrospective case-control study to determine the predictors of readmission.

Methods:... Read More about Female sex is associated with increased risk of early readmission with asthma in Staffordshire children.

The British Lung Foundation asthma management programme improving children's asthma control
Presentation / Conference
Gilchrist. The British Lung Foundation asthma management programme improving children's asthma control. Presented at ERS International Congress 2017

Background: The 10-year Finland asthma programme showed that educating healthcare workers, patients and families reduces hospital admissions and asthma-related deaths (1).

Aim: The Department of Health and the Scottish Government funded a 2-year p... Read More about The British Lung Foundation asthma management programme improving children's asthma control.