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Global impact of asthma on children and adolescents' daily lives: the room to breathe survey (2012)
Journal Article
(2012). Global impact of asthma on children and adolescents' daily lives: the room to breathe survey. Pediatric Pulmonology, 346-357. https://doi.org/10.1002/ppul.21557

Objective
To establish children and adolescents' perspectives regarding their asthma and its impact upon their daily lives.

Design
A 14-item questionnaire.

Setting
Canada, Greece, Hungary, The Netherlands, the United Kingdom, and South Afric... Read More about Global impact of asthma on children and adolescents' daily lives: the room to breathe survey.

Parent misperception of control in childhood/adolescent asthma: the Room to Breathe survey (2012)
Journal Article
(2012). Parent misperception of control in childhood/adolescent asthma: the Room to Breathe survey. European Respiratory Journal, 90-96. https://doi.org/10.1183/09031936.00048911

The aim of our study was to determine how often asthma control is achieved in children and adolescents, and how asthma affects parents' and children's daily lives.

Interviews, including the childhood asthma control test (C-ACT), were conducted wit... Read More about Parent misperception of control in childhood/adolescent asthma: the Room to Breathe survey.

Is there any evidence for influenza vaccination in children with asthma? (2007)
Journal Article
(2007). Is there any evidence for influenza vaccination in children with asthma?. Archives of Disease in Childhood, 644-645. https://doi.org/10.1136/adc.2007.117085

A 12 year old boy presents for a routine asthma follow-up appointment during the autumn. He takes 200 µg per day of inhaled budesonide and uses his salbutamol 3–4 times per week. His mother asks if the flu vaccine will make it less likely that he wil... Read More about Is there any evidence for influenza vaccination in children with asthma?.

Drug therapy in the management of acute asthma. (2007)
Journal Article
(2007). Drug therapy in the management of acute asthma. Archives of Disease in Childhood: Education & Practice, ep82 - ep86. https://doi.org/10.1136/adc.2006.107631

If our management of children with asthma was optimal, there would be no need for this article as we would be able to prevent the development and progression of any asthma exacerbation. In reality, we are quite a long way from optimal care of childho... Read More about Drug therapy in the management of acute asthma..

Effects of glutathione S-transferase M1, T1 and P1 on lung function in asthmatic families. (2005)
Journal Article
Carroll, W., Lenney, W., Jones, P., Strange, R., Child, F., Whyte, M., …Fryer, A. (2005). Effects of glutathione S-transferase M1, T1 and P1 on lung function in asthmatic families. Clinical and Experimental Allergy, 35(9), 1155 - 1161. https://doi.org/10.1111/j.1365-2222.2005.02313.x

RATIONALE: Previous data have suggested that glutathione-S-transferase (GST) genotypes are important in determining the rate of lung function growth in childhood. This effect was most marked in Caucasian children with asthma. OBJECTIVES: We investiga... Read More about Effects of glutathione S-transferase M1, T1 and P1 on lung function in asthmatic families..

Maternal glutathione S-transferase GSTP1 genotype is a specific predictor of phenotype in children with asthma. (2005)
Journal Article
Carroll, W., Lenney, W., Child, F., Strange, R., Jones, P., & Fryer, A. (2005). Maternal glutathione S-transferase GSTP1 genotype is a specific predictor of phenotype in children with asthma. Pediatric Allergy and Immunology, 16(1), 32 - 39. https://doi.org/10.1111/j.1399-3038.2005.00249.x

Maternal factors are known to influence the heritability and expression of asthma and atopy. We report the association of maternal, paternal and proband GSTP1 genotype with lung function in 145 Caucasian children with asthma. GSTP1 Val105/Val105 and... Read More about Maternal glutathione S-transferase GSTP1 genotype is a specific predictor of phenotype in children with asthma..

Randomized controlled trial of nebulized adrenaline in acute bronchiolitis. (2003)
Journal Article
(2003). Randomized controlled trial of nebulized adrenaline in acute bronchiolitis. Pediatric Allergy and Immunology, 134 - 139. https://doi.org/10.1034/j.1399-3038.2003.00014.x

Use of both l-epinephrine and racemic epinephrine (adrenaline) has improved clinical symptoms and composite respiratory scores in acute bronchiolitis. The objective of this randomized double-blind placebo-controlled study was to assess whether there... Read More about Randomized controlled trial of nebulized adrenaline in acute bronchiolitis..

Vitamin D supplementation for improving bone density in vitamin D-deficient children: a systematic review and individual participant data meta-analysis of randomized controlled trials
Presentation / Conference
Wu, F., El-Hajj Fuleihan, G., Cai, G., Lamberg-Allardt, C., Viljakainen, H. T., Rahme, M., …Winzenberg, T. Vitamin D supplementation for improving bone density in vitamin D-deficient children: a systematic review and individual participant data meta-analysis of randomized controlled trials. Presented at Journal of Bone and Mineral Research

'Meeting Abstract'

Incidence of post-procedure complications in children undergoing elective flexible bronchoscopy
Presentation / Conference
Gilchrist. Incidence of post-procedure complications in children undergoing elective flexible bronchoscopy. Presented at ERS International Congress 2019

Background: Paediatric flexible bronchoscopy with bronchoalveolar lavage (FB-BAL) is a safe procedure with a low incidence of intra-procedure complications. There is a paucity of data on the incidence of post-procedure complications.

Aim: To inves... Read More about Incidence of post-procedure complications in children undergoing elective flexible bronchoscopy.

The British Lung Foundation asthma management programme improving children's asthma control
Presentation / Conference
Gilchrist. The British Lung Foundation asthma management programme improving children's asthma control. Presented at ERS International Congress 2017

Background: The 10-year Finland asthma programme showed that educating healthcare workers, patients and families reduces hospital admissions and asthma-related deaths (1).

Aim: The Department of Health and the Scottish Government funded a 2-year p... Read More about The British Lung Foundation asthma management programme improving children's asthma control.

Female sex is associated with increased risk of early readmission with asthma in Staffordshire children
Presentation / Conference
Gilchrist. Female sex is associated with increased risk of early readmission with asthma in Staffordshire children. Presented at ERS International Congress 2017

Background: Asthma is the commonest medical reason for a child to be admitted to hospital in the UK. c.15% are readmitted within 3 months.

Aim: We undertook a retrospective case-control study to determine the predictors of readmission.

Methods:... Read More about Female sex is associated with increased risk of early readmission with asthma in Staffordshire children.