Skip to main content

Research Repository

Advanced Search

Dementia, Treatment Decisions, and the UN Convention on the Rights of Persons With Disabilities. A New Framework for Old Problems (2020)
Journal Article
De Sabbata. (2020). Dementia, Treatment Decisions, and the UN Convention on the Rights of Persons With Disabilities. A New Framework for Old Problems. Frontiers in Psychiatry, 11, https://doi.org/10.3389/fpsyt.2020.571722

The UN Convention on the Rights of Persons with Disabilities has been at the center of considerable debate in the field of mental health. The discussion has caught up in particular after the publication of General Comment No. 1 in which the Committee... Read More about Dementia, Treatment Decisions, and the UN Convention on the Rights of Persons With Disabilities. A New Framework for Old Problems.

Is it time for biocatalysis in fragment-based drug discovery? (2020)
Journal Article
Cosgrove. (2020). Is it time for biocatalysis in fragment-based drug discovery?. Chemical Science, 11104 - 11112. https://doi.org/10.1039/D0SC04103C

The use of biocatalysts for fragment-based drug discovery has yet to be fully investigated, despite the promise enzymes hold for the synthesis of poly-functional, non-protected small molecules. Here we analyze products of the biocatalysis literature... Read More about Is it time for biocatalysis in fragment-based drug discovery?.

Prevalence, Characteristics and Clinical Course of Neuropathic Pain in Primary Care Patients Consulting with Low Back-related Leg Pain. (2020)
Journal Article
Dunn. (2020). Prevalence, Characteristics and Clinical Course of Neuropathic Pain in Primary Care Patients Consulting with Low Back-related Leg Pain. Clinical Journal of Pain, https://doi.org/10.1097/AJP.0000000000000879

OBJECTIVES: Little is known about the epidemiology of neuropathic pain in primary care patients consulting with low back-related leg pain. We aimed to describe prevalence, characteristics and clinical course of low back-related leg pain patients with... Read More about Prevalence, Characteristics and Clinical Course of Neuropathic Pain in Primary Care Patients Consulting with Low Back-related Leg Pain..

Scarlett Letter: A study based on experience of stigma by COVID-19 patients in quarantine (2020)
Journal Article
Farooq. (2020). Scarlett Letter: A study based on experience of stigma by COVID-19 patients in quarantine. https://doi.org/10.12669/pjms.36.7.3606

Background and Objectives: Stigma around COVID-19 is a major barrier in global efforts to control the COVID 19 pandemic. Limited data is available regarding stigma faced by COVID-19 patients in low- and middle-income countries (LMIC).... Read More about Scarlett Letter: A study based on experience of stigma by COVID-19 patients in quarantine.

Public Health and Risk Communication During COVID-19—Enhancing Psychological Needs to Promote Sustainable Behavior Change (2020)
Journal Article
Porat, T., Nyrup, R., Calvo, R. A., Paudyal, P., & Ford, E. (2020). Public Health and Risk Communication During COVID-19—Enhancing Psychological Needs to Promote Sustainable Behavior Change. Frontiers in Public Health, https://doi.org/10.3389/fpubh.2020.573397

Background: The current COVID-19 pandemic requires sustainable behavior change to mitigate the impact of the virus. A phenomenon which has arisen in parallel with this pandemic is an infodemic—an over-abundance of information, of which some is accura... Read More about Public Health and Risk Communication During COVID-19—Enhancing Psychological Needs to Promote Sustainable Behavior Change.

Feasibility study for supporting medication adherence for adults with cystic fibrosis: mixed-methods process evaluation. (2020)
Journal Article
Hind, D., Drabble, S., Arden, M., Mandefield, L., Waterhouse, S., Maguire, C., …O'Cathain, A. (2020). Feasibility study for supporting medication adherence for adults with cystic fibrosis: mixed-methods process evaluation. BMJ Open, e039089 - ?. https://doi.org/10.1136/bmjopen-2020-039089

OBJECTIVES: To undertake a process evaluation of an adherence support intervention for people with cystic fibrosis (PWCF), to assess its feasibility and acceptability. SETTING: Two UK cystic fibrosis (CF) units. PARTICIPANTS: Fourteen adult PWCF; thr... Read More about Feasibility study for supporting medication adherence for adults with cystic fibrosis: mixed-methods process evaluation..

Assessment of fracture risk tools in care home residents: a multi-centre observational pilot study (2020)
Journal Article
Ihama, F., Pandyan, A., & Roffe, C. (2020). Assessment of fracture risk tools in care home residents: a multi-centre observational pilot study. European Geriatric Medicine, 12, 79-89. https://doi.org/10.1007/s41999-020-00383-2

Background
Fragility fractures are common in care home residents but established tools have not been tested in this population. Aim: To identify the most practicable tool for use.

Methods
Design
Multicentre prospective observational cohort pilo... Read More about Assessment of fracture risk tools in care home residents: a multi-centre observational pilot study.

The Added Value of Radiographs in Diagnosing Knee Osteoarthritis Is Similar for General Practitioners and Secondary Care Physicians; Data from the CHECK Early Osteoarthritis Cohort. (2020)
Journal Article
(2020). The Added Value of Radiographs in Diagnosing Knee Osteoarthritis Is Similar for General Practitioners and Secondary Care Physicians; Data from the CHECK Early Osteoarthritis Cohort. Journal of Clinical Medicine, https://doi.org/10.3390/jcm9103374

OBJECTIVE: The purpose of this study was to evaluate the added value of radiographs for diagnosing knee osteoarthritis (KOA) by general practitioners (GPs) and secondary care physicians (SPs). METHODS: Seventeen GPs and nineteen SPs were recruited to... Read More about The Added Value of Radiographs in Diagnosing Knee Osteoarthritis Is Similar for General Practitioners and Secondary Care Physicians; Data from the CHECK Early Osteoarthritis Cohort..

The efficacy of appropriate paper-based technology for Kenyan children with cerebral palsy. (2020)
Journal Article
Samia, P., Williams, F., Taylor, S., Lindoewood, R., Barton, C., & Buckley, J. (2020). The efficacy of appropriate paper-based technology for Kenyan children with cerebral palsy. Disability and Rehabilitation: Assistive Technology, 1 - 11. https://doi.org/10.1080/17483107.2020.1830442

PURPOSE: Appropriate paper-based technology (APT) is used to provide postural support for children with cerebral palsy (CP) in low-resourced settings. This pilot study aimed to evaluate the impact of APT on the children's and families' lives. MATERIA... Read More about The efficacy of appropriate paper-based technology for Kenyan children with cerebral palsy..

Evidence-based treatment recommendations for neck and low back pain across Europe: A systematic review of guidelines. (2020)
Journal Article
Corp, N., Mansell, G., Stynes, S., Wynne-Jones, G., Morsø, L., Hill, J., & Van Der Windt, D. (2021). Evidence-based treatment recommendations for neck and low back pain across Europe: A systematic review of guidelines. European Journal of Pain, 25(2), https://doi.org/10.1002/ejp.1679

Background and objective: This systematic review synthesised evidence from European neck and low back pain (NLBP) clinical practice guidelines (CPGs) to identify recommended treatment options for use across Europe. Databases and Data Treatment: Compr... Read More about Evidence-based treatment recommendations for neck and low back pain across Europe: A systematic review of guidelines..

Responders to Exercise Therapy in Patients with Osteoarthritis of the Hip: A Systematic Review and Meta-Analysis. (2020)
Journal Article
(2020). Responders to Exercise Therapy in Patients with Osteoarthritis of the Hip: A Systematic Review and Meta-Analysis. International Journal of Environmental Research and Public Health, https://doi.org/10.3390/ijerph17207380

The Outcome Measures in Rheumatology workgroup (OMERACT), together with the Osteoarthritis Research Society International (OARSI) developed the OMERACT-OARSI responder criteria. These criteria are used to determine if a patient with osteoarthritis (O... Read More about Responders to Exercise Therapy in Patients with Osteoarthritis of the Hip: A Systematic Review and Meta-Analysis..

Physiotherapists may improve management of knee osteoarthritis through greater psychosocial focus, being proactive with advice, and offering longer-term reviews: a qualitative study. (2020)
Journal Article
Dziedzic. (2020). Physiotherapists may improve management of knee osteoarthritis through greater psychosocial focus, being proactive with advice, and offering longer-term reviews: a qualitative study. Journal of Physiotherapy, https://doi.org/10.1016/j.jphys.2020.09.005

QUESTIONS: What are the experiences of physiotherapists delivering care for people with knee osteoarthritis? How do these experiences align with the national Clinical Care Standard? DESIGN: A qualitative study using individual interviews. PARTICIPANT... Read More about Physiotherapists may improve management of knee osteoarthritis through greater psychosocial focus, being proactive with advice, and offering longer-term reviews: a qualitative study..

Perspectives on public involvement in health research from Singapore: The potential of a supported group model of involvement. (2020)
Journal Article
(2020). Perspectives on public involvement in health research from Singapore: The potential of a supported group model of involvement. Health Expectations, 1074 - 1085. https://doi.org/10.1111/hex.13058

BACKGROUND: Singapore is an international research hub, with an emphasis on translational clinical research. Despite growing evidence of the positive impact of public involvement (PPI) in research, it remains rare in Singapore. AIMS: To investigate S... Read More about Perspectives on public involvement in health research from Singapore: The potential of a supported group model of involvement..

Identification of Patterns of Foot and Ankle Pain in the Community: Cross-sectional Findings from the Clinical Assessment Study of the Foot (2020)
Journal Article
Chean, C. S., Lingham, A., Rathod-Mistry, T., Thomas, M. J., Marshall, M., Menz, H. B., & Roddy, E. (2021). Identification of Patterns of Foot and Ankle Pain in the Community: Cross-sectional Findings from the Clinical Assessment Study of the Foot. Musculoskeletal Care, 19(1), https://doi.org/10.1002/msc.1502

Objectives: To investigate patterns of foot and ankle pain locations and symptoms, socio-demographic and comorbid characteristics to examine whether there are distinct foot and ankle pain phenotypes. Methods: Adults aged =50 years registered with fou... Read More about Identification of Patterns of Foot and Ankle Pain in the Community: Cross-sectional Findings from the Clinical Assessment Study of the Foot.

Clinical features and outcomes of adults with COVID-19: A systematic review and pooled analysis of the literature (2020)
Journal Article
Mallen. (2020). Clinical features and outcomes of adults with COVID-19: A systematic review and pooled analysis of the literature. International Journal of Clinical Practice, https://doi.org/10.1111/ijcp.13725

Background: The 2019 coronavirus disease (COVID-19) has become a global pandemic and the published literature describing the virus has grown exponentially.
Methods: We conducted a systematic review of the literature to identify the symptoms, comorb... Read More about Clinical features and outcomes of adults with COVID-19: A systematic review and pooled analysis of the literature.

The national Targeted Lung Health Checks programme: Focusing on the lungs does not mean missing adrenal lesions. (2020)
Journal Article
Hussain, I., Fryer, A. A., Barnett, J., & Hanna, F. W. (2020). The national Targeted Lung Health Checks programme: Focusing on the lungs does not mean missing adrenal lesions. Clinical Medicine, e202 - e203. https://doi.org/10.7861/clinmed.2020-0231

Recently, the UK's national Targeted Lung Health Checks programme produced recommendations for the management of incidental findings identified during the scans performed as part of the lung cancer screening programme. We identified significant discr... Read More about The national Targeted Lung Health Checks programme: Focusing on the lungs does not mean missing adrenal lesions..

Recent Advances and Future Perspectives in the Development of Therapeutic Approaches for Neurodegenerative Diseases (2020)
Journal Article
Bowerman, M. (2020). Recent Advances and Future Perspectives in the Development of Therapeutic Approaches for Neurodegenerative Diseases. Brain Sciences, 10(9), Article 633. https://doi.org/10.3390/brainsci10090633

Note: In lieu of an abstract, this is an excerpt from the first page.

Neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and Huntington’s disease (HD), severely impact the function of neuronal cells in the brain... Read More about Recent Advances and Future Perspectives in the Development of Therapeutic Approaches for Neurodegenerative Diseases.