Analysis of the dynamics of temporal relationships of neural activities using optical imaging data (2016)
Journal Article
(2016). Analysis of the dynamics of temporal relationships of neural activities using optical imaging data. Journal of Computational Neuroscience, 107-121. https://doi.org/10.1007/s10827-016-0630-8

The temporal relationship between the activities of neurons in biological neural systems is critically important for the correct delivery of the functionality of these systems. Fine measurement of temporal relationships of neural activities using mic... Read More about Analysis of the dynamics of temporal relationships of neural activities using optical imaging data.

19 F labelled glycosaminoglycan probes for solution NMR and non-linear (CARS) microscopy (2016)
Journal Article
Lima, M. A., Cavalheiro, R. P., Viana, G. M., Meneghetti, M. C., Rudd, T. R., Skidmore, M., …Yates, E. A. (2016). 19 F labelled glycosaminoglycan probes for solution NMR and non-linear (CARS) microscopy. Glycoconjugate Journal, 34, 405-410. https://doi.org/10.1007/s10719-016-9723-x

Studying polysaccharide-protein interactions under physiological conditions by conventional techniques is challenging. Ideally, macromolecules could be followed by both in vitro spectroscopy experiments as well as in tissues using microscopy, to enab... Read More about 19 F labelled glycosaminoglycan probes for solution NMR and non-linear (CARS) microscopy.

Critical Mutation Rate has an Exponential Dependence on Population Size for Eukaryotic-Length Genomes (2016)
Book Chapter
(2016). Critical Mutation Rate has an Exponential Dependence on Population Size for Eukaryotic-Length Genomes. In Proceedings of the Artificial Life Conference 2016 (172-179)

Impact of Deuteration on the Assembly Kinetics of Transthyretin Monitored by Native Mass Spectrometry and Implications for Amyloidoses. (2016)
Journal Article
(2016). Impact of Deuteration on the Assembly Kinetics of Transthyretin Monitored by Native Mass Spectrometry and Implications for Amyloidoses. Angewandte Chemie International Edition, 9438-9442. https://doi.org/10.1002/ange.201602747

It is well established that the formation of transthyretin (TTR) amyloid fibrils is linked to the destabilization and dissociation of its tetrameric structure into insoluble aggregates. Isotope labeling is used for the study of TTR by NMR, neutron di... Read More about Impact of Deuteration on the Assembly Kinetics of Transthyretin Monitored by Native Mass Spectrometry and Implications for Amyloidoses..

A Pilot Study of Ion - Molecule Reactions at Temperatures Relevant to the Atmosphere of Titan (2016)
Journal Article
(2016). A Pilot Study of Ion - Molecule Reactions at Temperatures Relevant to the Atmosphere of Titan. Origins of Life and Evolution of Biospheres, 533-538. https://doi.org/10.1007/s11084-016-9499-9

Reliable theoretical models of the chemical kinetics of the ionosphere of Saturn's moon, Titan, is highly dependent on the precision of the rates of the reactions of ambient ions with hydrocarbon molecules at relevant temperatures. A Variable Tempera... Read More about A Pilot Study of Ion - Molecule Reactions at Temperatures Relevant to the Atmosphere of Titan.

Unique Insights in the Cervicovaginal Lactobacillus iners and L. crispatus Proteomes and Their Associations with Microbiota Dysbiosis. (2016)
Journal Article
Wastling. (2016). Unique Insights in the Cervicovaginal Lactobacillus iners and L. crispatus Proteomes and Their Associations with Microbiota Dysbiosis. PloS one, e0150767 -?. https://doi.org/10.1371/journal.pone.0150767

BACKGROUND: A Lactobacillus-dominated cervicovaginal microbiota (VMB) protects women from adverse reproductive health outcomes, but the role of L. iners in the VMB is poorly understood. Our aim was to explore the association between the cervicovagina... Read More about Unique Insights in the Cervicovaginal Lactobacillus iners and L. crispatus Proteomes and Their Associations with Microbiota Dysbiosis..

Identification of Novel O-Linked Glycosylated Toxoplasma Proteins by Vicia villosa Lectin Chromatography. (2016)
Journal Article
(2016). Identification of Novel O-Linked Glycosylated Toxoplasma Proteins by Vicia villosa Lectin Chromatography. PloS one, e0150561 -?. https://doi.org/10.1371/journal.pone.0150561

Toxoplasma gondii maintains its intracellular life cycle using an extraordinary arsenal of parasite-specific organelles including the inner membrane complex (IMC), rhoptries, micronemes, and dense granules. While these unique compartments play critic... Read More about Identification of Novel O-Linked Glycosylated Toxoplasma Proteins by Vicia villosa Lectin Chromatography..

The Long and the Short of Mate Attraction in a Psylloid: do Semiochemicals Mediate Mating in Aacanthocnema dobsoni Froggatt? (2016)
Journal Article
Drijfhout. (2016). The Long and the Short of Mate Attraction in a Psylloid: do Semiochemicals Mediate Mating in Aacanthocnema dobsoni Froggatt?. Journal of Chemical Ecology, 163 -172. https://doi.org/10.1007/s10886-016-0674-2

Mating is preceded by a series of interdependent events that can be broadly categorized into searching and courtship. Long-range signals convey species- and sex-specific information during searching, while short-range signals provide information spec... Read More about The Long and the Short of Mate Attraction in a Psylloid: do Semiochemicals Mediate Mating in Aacanthocnema dobsoni Froggatt?.

Water Dynamics in Shewanella oneidensis at Ambient and High Pressure using Quasi-Elastic Neutron Scattering (2016)
Journal Article
(2016). Water Dynamics in Shewanella oneidensis at Ambient and High Pressure using Quasi-Elastic Neutron Scattering. Scientific reports, 18862 -?. https://doi.org/10.1038/srep18862

Quasielastic neutron scattering (QENS) is an ideal technique for studying water transport and relaxation dynamics at pico- to nanosecond timescales and at length scales relevant to cellular dimensions. Studies of high pressure dynamic effects in live... Read More about Water Dynamics in Shewanella oneidensis at Ambient and High Pressure using Quasi-Elastic Neutron Scattering.

Transfection with thymidine kinase permits bromodeoxyuridine labelling of DNA replication in the human malaria parasite Plasmodium falciparum (2015)
Journal Article
(2015). Transfection with thymidine kinase permits bromodeoxyuridine labelling of DNA replication in the human malaria parasite Plasmodium falciparum. Malaria Journal, 490-?. https://doi.org/10.1186/s12936-015-1014-7

Background
Plasmodium falciparum, the causative agent of severe human malaria, is an early-diverging protozoan whose lifecycle has many unusual features, including its modes of replication. Research on the Plasmodium cell cycle, which occurs primari... Read More about Transfection with thymidine kinase permits bromodeoxyuridine labelling of DNA replication in the human malaria parasite Plasmodium falciparum.

Picomolar Inhibition of Plasmepsin V, an Essential Malaria Protease, Achieved Exploiting the Prime Region (2015)
Journal Article
Russo. (2015). Picomolar Inhibition of Plasmepsin V, an Essential Malaria Protease, Achieved Exploiting the Prime Region. PloS one, e0142509 - e0142509. https://doi.org/10.1371/journal.pone.0142509

Malaria is an infectious disease caused by Plasmodium parasites. It results in an annual death-toll of ~ 600,000. Resistance to all medications currently in use exists, and novel antimalarial drugs are urgently needed. Plasmepsin V (PmV) is an essent... Read More about Picomolar Inhibition of Plasmepsin V, an Essential Malaria Protease, Achieved Exploiting the Prime Region.

Peroxyl radical reactions with carotenoids in microemulsions: Influence of microemulsion composition and the nature of peroxyl radical precursor (2015)
Journal Article
(2015). Peroxyl radical reactions with carotenoids in microemulsions: Influence of microemulsion composition and the nature of peroxyl radical precursor. Free Radical Biology and Medicine, 75-84. https://doi.org/10.1016/j.freeradbiomed.2015.10.427

The reactions of acetylperoxyl radicals with different carotenoids (7,7'-dihydro-ß-carotene and ?-carotene) in SDS and CTAC microemulsions of different compositions were investigated using laser flash photolysis (LFP) coupled with kinetic absorption... Read More about Peroxyl radical reactions with carotenoids in microemulsions: Influence of microemulsion composition and the nature of peroxyl radical precursor.

Odorant receptor-based discovery of natural repellents of human lice (2015)
Journal Article
(2015). Odorant receptor-based discovery of natural repellents of human lice. Journal of Chemical Ecology, 103 - 109. https://doi.org/10.1016/j.ibmb.2015.10.009

The body louse, Pediculus humanus humanus, is an obligate blood-feeding ectoparasite and an important insect vector that mediates the transmission of diseases to humans. The analysis of the body louse genome revealed a drastic reduction of the chemos... Read More about Odorant receptor-based discovery of natural repellents of human lice.

Treatment of Experimental Arthritis with Mesenchymal Stem Cell Conditioned Medium (2015)
Journal Article
Kehoe, O., Kay, A., Rump-Goodrich, L., & Middleton, J. (2015). Treatment of Experimental Arthritis with Mesenchymal Stem Cell Conditioned Medium. Tissue engineering. Part A, S74 - S75

De novo Transcriptome Assemblies of Rana (Lithobates) catesbeiana and Xenopus laevis Tadpole Livers for Comparative Genomics without Reference Genomes (2015)
Journal Article
(2015). De novo Transcriptome Assemblies of Rana (Lithobates) catesbeiana and Xenopus laevis Tadpole Livers for Comparative Genomics without Reference Genomes. PloS one, e0130720 -?. https://doi.org/10.1371/journal.+pone.0130720

In this work we studied the liver transcriptomes of two frog species, the American bullfrog (Rana (Lithobates) catesbeiana) and the African clawed frog (Xenopus laevis). We used high throughput RNA sequencing (RNA-seq) data to assemble and annotate t... Read More about De novo Transcriptome Assemblies of Rana (Lithobates) catesbeiana and Xenopus laevis Tadpole Livers for Comparative Genomics without Reference Genomes.

Human mesenchymal stem cells stimulate EaHy926 endothelial cell migration: combined proteomic and in vitro analysis of the influence of donor-donor variability (2015)
Journal Article
Walter, M., Kohli, N., Major, T., Fuller, H., Wright, K., Kuiper, J., & Johnson, W. (2015). Human mesenchymal stem cells stimulate EaHy926 endothelial cell migration: combined proteomic and in vitro analysis of the influence of donor-donor variability. Journal of Stem Cells and Regenerative Medicine, 11(1), 18-24. https://doi.org/10.46582/jsrm.1101004

Mesenchymal stem cells (MSCs) stimulate angiogenesis within a wound environment and this effect is mediated through paracrine interactions with the endothelial cells present. Here we report that human MSC-conditioned medium (n=3 donors) significantly... Read More about Human mesenchymal stem cells stimulate EaHy926 endothelial cell migration: combined proteomic and in vitro analysis of the influence of donor-donor variability.

Marshalin, a microtubule minus-end binding protein, regulates cytoskeletal structure in the organ of Corti (2013)
Journal Article
(2013). Marshalin, a microtubule minus-end binding protein, regulates cytoskeletal structure in the organ of Corti. Biology open BiO / Company of Biologists, 1192 -1202. https://doi.org/10.1242/bio.20135603

Dramatic structural changes in microtubules (MT) and the assembly of complicated intercellular connections are seen during the development of the cellular matrix of the sense organ for hearing, the organ of Corti. This report examines the expression... Read More about Marshalin, a microtubule minus-end binding protein, regulates cytoskeletal structure in the organ of Corti.

Imaging African trypanosomes (2013)
Journal Article
MacLean, L., Myburgh, E., Rodgers, J., & Price, H. (2013). Imaging African trypanosomes. Parasite immunology, 35(9-10), 283 -294. https://doi.org/10.1111/pim.12046

Trypanosoma brucei are extracellular kinetoplastid parasites transmitted by the blood-sucking tsetse fly. They are responsible for the fatal disease human African trypanosomiasis (HAT), also known as sleeping sickness. In late-stage infection, trypan... Read More about Imaging African trypanosomes.

Prothymosin a overexpression contributes to the development of pulmonary emphysema (2013)
Journal Article
Wu. (2013). Prothymosin a overexpression contributes to the development of pulmonary emphysema. Nature communications, https://doi.org/10.1038/ncomms2906

Emphysema is one of the disease conditions that comprise chronic obstructive pulmonary disease. Prothymosin a transgenic mice exhibit an emphysema phenotype, but the pathophysiological role of prothymosin a in emphysema remains unclear. Here we show... Read More about Prothymosin a overexpression contributes to the development of pulmonary emphysema.

Evaluation of bioluminescence-based assays of anti-malarial drug activity (2013)
Journal Article
Horrocks. (2013). Evaluation of bioluminescence-based assays of anti-malarial drug activity. Malaria Journal, 58 - ?. https://doi.org/10.1186/1475-2875-12-58

Transgenic Plasmodium falciparum expressing luciferase offers an attractive bioluminescence-based assay platform for the investigation of the pharmacological properties of anti-malarial drugs. Here a side-by-side comparison of bioluminescence and flu... Read More about Evaluation of bioluminescence-based assays of anti-malarial drug activity.