Neuropathic pain in low back-related leg pain patients: What is the evidence of prevalence, characteristics, and prognosis in primary care? A systematic review of the literature. (2017)
Journal Article
Stynes, S., Dunn, K., Foster, N., Konstantinou, K., & Harrisson, S. (2017). Neuropathic pain in low back-related leg pain patients: What is the evidence of prevalence, characteristics, and prognosis in primary care? A systematic review of the literature. Journal of Pain, 1295-1312. https://doi.org/10.1016/j.jpain.2017.04.012

This systematic review synthesizes literature describing prevalence, characteristics and prognosis of low back-related leg pain (LBLP) patients with neuropathic pain in primary care and/or similar settings. Inclusion and exclusion criteria were devel... Read More about Neuropathic pain in low back-related leg pain patients: What is the evidence of prevalence, characteristics, and prognosis in primary care? A systematic review of the literature..

Effect of a model consultation informed by guideline on recorded quality of care of osteoarthritis (MOSAICS): a cluster randomised controlled trial in primary care (2017)
Journal Article
Jordan, K., Edwards, J., Porcheret, M., Healey, E., Jinks, C., Bedson, J., …Dziedzic, K. (2017). Effect of a model consultation informed by guideline on recorded quality of care of osteoarthritis (MOSAICS): a cluster randomised controlled trial in primary care. Osteoarthritis and Cartilage, 25(10), 1588-1597. https://doi.org/10.1016/j.joca.2017.05.017

Objective
To determine the effect of a model osteoarthritis (OA) consultation (MOAC) informed by National Institute for Health and Care Excellence (NICE) recommendations compared with usual care on recorded quality of care of clinical OA in general... Read More about Effect of a model consultation informed by guideline on recorded quality of care of osteoarthritis (MOSAICS): a cluster randomised controlled trial in primary care.

Consultation patterns of children and adolescents with knee pain in UK general practice: analysis of medical records (2017)
Journal Article
Campbell, P., Protheroe, J., Rajani, A., Dunn, K., & Michaleff, Z. (2017). Consultation patterns of children and adolescents with knee pain in UK general practice: analysis of medical records. BMC Musculoskeletal Disorders, https://doi.org/10.1186/s12891-017-1586-1

Background
Knee problems are common in children and adolescents. Despite this, little is known about the epidemiology of knee problems in children and adolescents who consult in general practice. The aim of this study was to describe consultations b... Read More about Consultation patterns of children and adolescents with knee pain in UK general practice: analysis of medical records.

Chest pain and shortness of breath in cardiovascular disease: a prospective cohort study in UK primary care (2017)
Journal Article
Barnett, L. A., Prior, J. A., Kadam, U. T., & Jordan, K. P. (2017). Chest pain and shortness of breath in cardiovascular disease: a prospective cohort study in UK primary care. BMJ Open, 7(5), Article e015857. https://doi.org/10.1136/bmjopen-2017-015857

OBJECTIVE: To determine characteristics associated with monthly chest pain and shortness of breath (SoB) during activity in cardiovascular disease (CVD) and trajectories of these symptoms over 10 months. STUDY DESIGN AND SETTING: Baseline questionnai... Read More about Chest pain and shortness of breath in cardiovascular disease: a prospective cohort study in UK primary care.

Does metformin protect against osteoarthritis? An electronic health record cohort study (2017)
Journal Article
Barnett, L. A., Jordan, K. P., Edwards, J. J., & Van Der Windt, D. A. (2017). Does metformin protect against osteoarthritis? An electronic health record cohort study. Primary Health Care Research and Development, 623-628. https://doi.org/10.1017/s1463423617000287

Background
Obesity is a major risk factor for osteoarthritis (OA) whilst there is some evidence that diabetes also increases risk. Metformin is a common oral treatment for those with diabetes.

Objective
The aim is to investigate whether metformi... Read More about Does metformin protect against osteoarthritis? An electronic health record cohort study.

The diagnosis and management of a vertebral artery loop causing cervical radiculopathy (2017)
Journal Article
(2017). The diagnosis and management of a vertebral artery loop causing cervical radiculopathy. European Spine Journal, https://doi.org/10.1007/s00586-017-5123-6

Background
Cervical radiculopathies are rarely caused by vertebral artery loop formation, which is estimated to be present in less than 3% of patients. It is uncertain what causes the loop formation: some propose an association with spondylotic chan... Read More about The diagnosis and management of a vertebral artery loop causing cervical radiculopathy.

Are sleep problems a risk factor for the onset of musculoskeletal pain in children and adolescents? A systematic review (2017)
Journal Article
Dunn, K., Andreucci, A., & Campbell, P. (2017). Are sleep problems a risk factor for the onset of musculoskeletal pain in children and adolescents? A systematic review. SLEEP, https://doi.org/10.1093/sleep/zsx093

Study Objectives:
Musculoskeletal pain is a major burden on the society. Adults with sleep problems are at higher risk of musculoskeletal pain onset, but there is no evidence for this relationship in children and adolescents. This study aimed to sys... Read More about Are sleep problems a risk factor for the onset of musculoskeletal pain in children and adolescents? A systematic review.

Affective concordance in couples: a cross-sectional analysis of depression and anxiety consultations within a population of 13,507 couples in primary care (2017)
Journal Article
Walker, J., Liddle, J., Jordan, K., & Campbell, P. (2017). Affective concordance in couples: a cross-sectional analysis of depression and anxiety consultations within a population of 13,507 couples in primary care. BMC Psychiatry, https://doi.org/10.1186/s12888-017-1354-7

Background
Depression and anxiety are common and have a significant impact on the individual and wider society. One theory proposed to explain a heightened risk for depression and anxiety is affective concordance in couples (e.g. influence of shared... Read More about Affective concordance in couples: a cross-sectional analysis of depression and anxiety consultations within a population of 13,507 couples in primary care.

Patient experiences, attitudes and expectations towards receiving information about anti-TNF medication: a quantitative study (2017)
Journal Article
(2017). Patient experiences, attitudes and expectations towards receiving information about anti-TNF medication: a quantitative study. Clinical Rheumatology, 2595-2600. https://doi.org/10.1007/s10067-017-3642-5

The objective of the study was to measure patient attitudes and experience of information received during drug counselling for rheumatoid arthritis (RA) medications. This is a cross-sectional UK postal questionnaire study. Three RA patient groups—dis... Read More about Patient experiences, attitudes and expectations towards receiving information about anti-TNF medication: a quantitative study.

Economic evaluation of strategies for restarting anticoagulation therapy after a first event of unprovoked venous thromboembolism. (2017)
Journal Article
(2017). Economic evaluation of strategies for restarting anticoagulation therapy after a first event of unprovoked venous thromboembolism. Journal of Thrombosis and Haemostasis, 1591-1600. https://doi.org/10.1111/jth.13739

BACKGROUND: Following at least three months of anticoagulation therapy after a first unprovoked Venous Thromboembolism (VTE), there is uncertainty about the duration of therapy. Further anticoagulation therapy reduces the risk of having a potentially... Read More about Economic evaluation of strategies for restarting anticoagulation therapy after a first event of unprovoked venous thromboembolism..

Development of an international comorbidity education framework (2017)
Journal Article
Lawson, C., Pati, S., Green, J., Messina, G., Strömberg, A., Nante, N., …Kadam, U. (2017). Development of an international comorbidity education framework. Nurse Education Today, 55, 82-89. https://doi.org/10.1016/j.nedt.2017.05.011

Context
The increasing number of people living with multiple chronic conditions in addition to an index condition has become an international healthcare priority. Health education curricula have been developed alongside single condition frameworks i... Read More about Development of an international comorbidity education framework.

Patient involvement vs. patient participation in qualitative research in the development of PROMs (2017)
Journal Article
(2017). Patient involvement vs. patient participation in qualitative research in the development of PROMs. Health Expectations, 371 - 372. https://doi.org/10.1111/hex.12459

No abstract

Patient involvement in research – participants or collaborators? (2017)
Journal Article
Chew-Graham, C. (2017). Patient involvement in research – participants or collaborators?. Health Expectations, 369 - 370. https://doi.org/10.1111/hex.12578

No abstract

Des caractéristiques de la goutte associées à la dépression mais pas à l’anxiété en soins primaires : conclusions initiales d’une étude de cohorte prospective (2017)
Journal Article
Mallen, Prior, Roddy, & Muller. (2017). Des caractéristiques de la goutte associées à la dépression mais pas à l’anxiété en soins primaires : conclusions initiales d’une étude de cohorte prospective. Revue du Rhumatisme, 84(5), 423-429. https://doi.org/10.1016/j.rhum.2017.05.004

Objectifs
Déterminer la prévalence de l’anxiété et de la dépression dans le contexte de la goutte, examiner les liens entre certaines caractéristiques de la goutte et ces comorbidités et identifier le rôle de l’allopurinol dans ces relations.

Mét... Read More about Des caractéristiques de la goutte associées à la dépression mais pas à l’anxiété en soins primaires : conclusions initiales d’une étude de cohorte prospective.

Cost-effectiveness of surgical interventions for the management of osteoarthritis: a systematic review of the literature (2017)
Journal Article
(2017). Cost-effectiveness of surgical interventions for the management of osteoarthritis: a systematic review of the literature. BMC Musculoskeletal Disorders, https://doi.org/10.1186/s12891-017-1540-2

Background
The primary purpose of this study is to assess the existing evidence on the cost-effectiveness of surgical interventions for the management of knee and hip osteoarthritis by systematically reviewing published economic evaluation studies.... Read More about Cost-effectiveness of surgical interventions for the management of osteoarthritis: a systematic review of the literature.

IL-6 promotes epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2/STAT3 signaling pathway. (2017)
Journal Article
Yu. (2017). IL-6 promotes epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2/STAT3 signaling pathway. American journal of physiology. Renal physiology, F310 - F318. https://doi.org/10.1152/ajprenal.00428.2016

Long-term peritoneal dialysis (PD) therapy results in functional and structural alteration of the peritoneal membrane, including epithelial-to-mesenchymal transition (EMT). Interleukin 6 (IL-6) is a local pleiotropic cytokine, hypothesized to play an... Read More about IL-6 promotes epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2/STAT3 signaling pathway..

Genetic and other risk factors for suicidal ideation and the relationship with depression (2017)
Journal Article
(2017). Genetic and other risk factors for suicidal ideation and the relationship with depression. Psychological Medicine, 2438-2449. https://doi.org/10.1017/s0033291717000940

There is a genetic contribution to the risk of suicide, but sparse prior research on the genetics of suicidal ideation.
Active and passive suicidal ideation were assessed in a Sri Lankan population-based twin registry (n = 3906 twins) and a matched... Read More about Genetic and other risk factors for suicidal ideation and the relationship with depression.

Casual mechanisms in the clinical course and treatment of back pain (2017)
Journal Article
(2017). Casual mechanisms in the clinical course and treatment of back pain. Best Practice and Research: Clinical Rheumatology, 1074-1083. https://doi.org/10.1016/j.berh.2017.04.001

In recent years, there has been increasing interest in studying causal mechanisms in the development and treatment of back pain. The aim of this article is to provide an overview of our current understanding of causal mechanisms in the field. In the... Read More about Casual mechanisms in the clinical course and treatment of back pain.

Potential health impact and cost-effectiveness of drug therapy for prehypertension (2017)
Journal Article
Yu. (2017). Potential health impact and cost-effectiveness of drug therapy for prehypertension. International Journal of Cardiology, 403-408. https://doi.org/10.1016/j.ijcard.2017.05.003

Background
Studies have reported that pharmacologic interventions with candesartan or ramipril could reduce the risk of hypertension among prehypertensive subjects free of clinical cardiovascular disease (CVD), however, the cost-effectiveness and lo... Read More about Potential health impact and cost-effectiveness of drug therapy for prehypertension.

Association between pulmonary function and renal function: findings from China and Australia. (2017)
Journal Article
Yu. (2017). Association between pulmonary function and renal function: findings from China and Australia. BMC Nephrology, https://doi.org/10.1186/s12882-017-0565-y

Background
The relationship between obstructive lung function and impaired renal function is unclear. This study investigated the dose-response relationship between obstructive lung function and impaired renal function.

Methods
Two independent c... Read More about Association between pulmonary function and renal function: findings from China and Australia..