Recent advances in the catalytic oxidation of alkene and alkane substrates using immobilized manganese complexes with nitrogen containing ligands (2019)
Journal Article
Nodzewska, A., Wadolowska, A., & Watkinson, M. (2019). Recent advances in the catalytic oxidation of alkene and alkane substrates using immobilized manganese complexes with nitrogen containing ligands. Coordination Chemistry Reviews, 382, 181-216. https://doi.org/10.1016/j.ccr.2018.12.004

In recent years, many supported manganese catalysts for the oxidative transformations of hydrocarbons by various terminal oxidants have been designed and tested. A vast range of inorganic (e.g. silica, carbon, zeolites), organic (e.g. polymers, dendr... Read More about Recent advances in the catalytic oxidation of alkene and alkane substrates using immobilized manganese complexes with nitrogen containing ligands.

Microwave Assisted Synthesis of Novel Bis-Flavone Dimers as New Anticancer Agents (2019)
Journal Article
McGown, A., Ragazzon-Smith, A., Hadfield, J. A., Potgetier, H., & Ragazzon, P. A. (2019). Microwave Assisted Synthesis of Novel Bis-Flavone Dimers as New Anticancer Agents. Letters in Organic Chemistry, 16(1), 66-75. https://doi.org/10.2174/1570178615666180621094529

In this study we describe a microwave based click chemistry method used to prepare a family of novel bis-flavone dimers. The substituted 7-hydroxy and 4’-hydroxy flavonoids were linked through a triazole ring. The compounds were easily synthesized an... Read More about Microwave Assisted Synthesis of Novel Bis-Flavone Dimers as New Anticancer Agents.

Simple and robust ion-selective electrodes for bio/environmental analysis (2018)
Thesis
Fayose, T. A. (2018). Simple and robust ion-selective electrodes for bio/environmental analysis. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/412313

Chemical sensors have gone through a lot of optimisation renaissance over the years to have come from a typical bench-top tool for measurements of ions in standard solutions, to a more promising analytical technique capable of measuring the activitie... Read More about Simple and robust ion-selective electrodes for bio/environmental analysis.

Exploring the reversible host-guest chemistry of a crystalline octanuclear Ag(I) metallosupramolecular macrocycle formed from a simple pyrazinylpyridine ligand (2018)
Journal Article
Hawes, C. S. (2018). Exploring the reversible host-guest chemistry of a crystalline octanuclear Ag(I) metallosupramolecular macrocycle formed from a simple pyrazinylpyridine ligand. Dalton Transactions, 17266-17275. https://doi.org/10.1039/C8DT04583F

Here we report the synthesis of two new 2-(2-pyrazinyl)pyridine ligands, and explore their coordination chemistry with Cu(ii) and Ag(i) ions, leading to the discovery of metallosupramolecular architectures of surprising complexity. Differing only in... Read More about Exploring the reversible host-guest chemistry of a crystalline octanuclear Ag(I) metallosupramolecular macrocycle formed from a simple pyrazinylpyridine ligand.

New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action. (2018)
Journal Article
Reynisson. (2018). New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action. Journal of Medicinal Chemistry, https://doi.org/10.1021/acs.jmedchem.8b01031

Six morpholine-(iso)thiosemicarbazone hybrids HL1-HL6 and their Cu(II) complexes with good-to-moderate solubility and stability in water were synthesized and characterized. Cu(II) complexes [Cu(L1-6)Cl] (1-6) formed weak dimeric associates in the sol... Read More about New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action..

Ketone Formation via Decarboxylation Reactions of Fatty Acids Using Solid Hydroxide/Oxide Catalysts (2018)
Journal Article
Smith, B., Li, L., Perera-Solis, D., Gildea, L., Zholobenko, V., Dyer, P., & Greenwell, H. (2018). Ketone Formation via Decarboxylation Reactions of Fatty Acids Using Solid Hydroxide/Oxide Catalysts. Inorganics, https://doi.org/10.3390/inorganics6040121

A sustainable route to ketones is described where stearone is produced via ketonic decarboxylation of stearic acid mediated by solid base catalysts in yields of up to 97%, at 250 °C. A range of Mg/Al layered double hydroxide (LDH) and mixed metal... Read More about Ketone Formation via Decarboxylation Reactions of Fatty Acids Using Solid Hydroxide/Oxide Catalysts.

Structural basis for activation of plasma-membrane Ca2+-ATPase by calmodulin. (2018)
Journal Article
(2018). Structural basis for activation of plasma-membrane Ca2+-ATPase by calmodulin. Communications Biology, 206 - ?. https://doi.org/10.1038/s42003-018-0203-7

Plasma-membrane Ca2+-ATPases expel Ca2+ from the cytoplasm and are key regulators of Ca2+ homeostasis in eukaryotes. They are autoinhibited under low Ca2+ concentrations. Calmodulin (CaM)-binding to a unique regulatory domain releases the autoinhibit... Read More about Structural basis for activation of plasma-membrane Ca2+-ATPase by calmodulin..

Harmonizing semantic annotations for computational models in biology (2018)
Journal Article
Misirli. (2018). Harmonizing semantic annotations for computational models in biology. Briefings in bioinformatics, bby087 - bby087. https://doi.org/10.1093/bib/bby087

Life science researchers use computational models to articulate and test hypotheses about the behavior of biological systems. Semantic annotation is a critical component for enhancing the interoperability and reusability of such models as well as for... Read More about Harmonizing semantic annotations for computational models in biology.

Computer modelling of pure and doped stoichiometric and congruent lithium niobate (2018)
Thesis
Hedges, E. E. (2018). Computer modelling of pure and doped stoichiometric and congruent lithium niobate. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/418120

This investigation has modelled lithium niobate in its congruent form, stoichiometric form and paraelectric phase to determine whether the preference of doping schemes changes, specifically when the concentration of a dopant is varied. Mott-Littleton... Read More about Computer modelling of pure and doped stoichiometric and congruent lithium niobate.

Investigations into the synthesis of heterocyclic compounds with biological applications (2018)
Thesis
Abid, H. A. (2018). Investigations into the synthesis of heterocyclic compounds with biological applications. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/412020

There is a growing body of literature that recognises the importance of tandem reactions, where a number of transformations are carried out in a one-pot process. Such reactions offer considerable benefits such as: a reduction in time, and the sequenc... Read More about Investigations into the synthesis of heterocyclic compounds with biological applications.

Enhanced methane reforming activity of a hydrothermally synthesised co-doped perovskite catalyst (2018)
Journal Article
Khazaal, M. H., Staniforth, J. Z., Alfatlawi, Z. A., Ormerod, R. M., & Darton, R. (2018). Enhanced methane reforming activity of a hydrothermally synthesised co-doped perovskite catalyst. Energy and Fuels, 32(12), 12826–12832. https://doi.org/10.1021/acs.energyfuels.8b02848

A catalyst for the direct reforming of methane and simulated biogas has been prepared using a green and low temperature hydrothermal method. The nickel and iron co-doped SrZrO3 perovskite shows catalytic activity comparable to 10% Ni/Al2O3, but with... Read More about Enhanced methane reforming activity of a hydrothermally synthesised co-doped perovskite catalyst.

Fourier transform infrared spectra of cells on glass coverslips: a further step in spectral pathology (2018)
Journal Article
Rutter, A., Crees, J., Wright, H., van Pittius, D., Yousef, I., & Sule-Suso, J. (2018). Fourier transform infrared spectra of cells on glass coverslips: a further step in spectral pathology. Analyst, 5711 - 5717. https://doi.org/10.1039/C8AN01634H

Over the last few years, great effort has been placed on developing Fourier Transform Infrared (FTIR) microspectroscopy as a tool to help in the histopathological diagnosis of cancer. The ever increasing workload in pathology departments is calling f... Read More about Fourier transform infrared spectra of cells on glass coverslips: a further step in spectral pathology.

Single-Source Bismuth (Transition Metal) Polyoxovanadate Precursors for the Scalable Synthesis of Doped BiVO4 Photoanodes (2018)
Journal Article
Lu, H., Andrei, V., Jenkinson, K., Regoutz, A., Li, N., Creissen, C., …Pike, S. (2018). Single-Source Bismuth (Transition Metal) Polyoxovanadate Precursors for the Scalable Synthesis of Doped BiVO4 Photoanodes. Advanced materials, 1804033 - 1804033. https://doi.org/10.1002/adma.201804033

Is callose required for silicification in plants? (2018)
Journal Article
(2018). Is callose required for silicification in plants?. Biology Letters, https://doi.org/10.1098/rsbl.2018.0338

The cell wall polymer callose catalyses the formation of silica in vitro and is heavily implicated in biological silicification in Equisetum (horsetail) and Arabidopsis (thale cress) in vivo Callose, a ß-1,3-glucan, is an ideal partner for silicifica... Read More about Is callose required for silicification in plants?.

Chemical Vapor Deposition of Tin Sulfide from Diorganotin(IV) Dixanthates (2018)
Journal Article
Al-Shakban, M., Matthews, P., Lewis, E., O'Brien, P., Haigh, S., Lewis, D., …Vitorica-Yrezabal, I. (2018). Chemical Vapor Deposition of Tin Sulfide from Diorganotin(IV) Dixanthates. Journal of Materials Science, https://doi.org/10.1007/s10853-018-2968-y

We report the synthesis and single-crystal X-ray characterization of diphenyltin bis(2-methoxyethylxanthate) and diphenyltin bis(iso-butylxanthate). These xanthates have been used as a single-source precursor to deposit tin chalcogenide thin films by... Read More about Chemical Vapor Deposition of Tin Sulfide from Diorganotin(IV) Dixanthates.

A Novel Class of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Contains the Octahydro-2H-chromen-4-ol Scaffold. (2018)
Journal Article
Li-Zhulanov, N. S., Zakharenko, A. L., Chepanova, A. A., Patel, J., Zafar, A., Volcho, K. P., …Lavrik, O. I. (2018). A Novel Class of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Contains the Octahydro-2H-chromen-4-ol Scaffold. Molecules, 23(10), Article 2468. https://doi.org/10.3390/molecules23102468

Tyrosyl-DNA phosphodiesterase 1 (Tdp1) is a DNA repair enzyme that mends topoisomerase 1-mediated DNA damage. Tdp1 is a current inhibition target for the development of improved anticancer treatments, as its inhibition may enhance the therapeutic eff... Read More about A Novel Class of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Contains the Octahydro-2H-chromen-4-ol Scaffold..

Highly diastereoselective boron and titanium mediated aldol reactions of a mannitol derived 2,3-butanediacetal ethyl ketone (2018)
Journal Article
O'Brien, M., Weber, A., Hardy, G., & Ley, S. (2018). Highly diastereoselective boron and titanium mediated aldol reactions of a mannitol derived 2,3-butanediacetal ethyl ketone. Tetrahedron, 5319 - 5329. https://doi.org/10.1016/j.tet.2018.06.041

A mannitol derived 2,3-butanediacetal ethyl ketone displays high levels of diastereoselectivity in boron and titanium mediated aldol reactions with a range of aliphatic and aromatic aldehydes to afford syn aldol products in high yield. The stereochem... Read More about Highly diastereoselective boron and titanium mediated aldol reactions of a mannitol derived 2,3-butanediacetal ethyl ketone.

Gas-liquid flow hydrogenation of nitroarenes: Efficient access to a pharmaceutically relevant pyrrolobenzo[1,4]diazepine scaffold (2018)
Journal Article
Dimitriou, E., Jones, R., Pritchard, R., Miller, G., & O'Brien, M. (2018). Gas-liquid flow hydrogenation of nitroarenes: Efficient access to a pharmaceutically relevant pyrrolobenzo[1,4]diazepine scaffold. Tetrahedron, 74(47), 6795-6803. https://doi.org/10.1016/j.tet.2018.09.025

Using a Tube-in-Tube device based on the amorphous Teflon AF-2400 fluoropolymer, a series of nitroarenes was hydrogenated to afford the corresponding aniline compounds. The system was then applied to the construction of a pyrrolobenzo[1,4]diazapene s... Read More about Gas-liquid flow hydrogenation of nitroarenes: Efficient access to a pharmaceutically relevant pyrrolobenzo[1,4]diazepine scaffold.

Nuclear magnetic resonance and small-angle X-ray scattering studies of mixed sodium dodecyl sulfate and N,N-dimethyldodecylamine N-oxide aqueous systems performed at low temperatures (2018)
Journal Article
Summerton, E., Hollamby, M., Duff, C., Thompson, E., Snow, T., Smith, A., …Britton, M. (2018). Nuclear magnetic resonance and small-angle X-ray scattering studies of mixed sodium dodecyl sulfate and N,N-dimethyldodecylamine N-oxide aqueous systems performed at low temperatures. Journal of Colloid and Interface Science, 535(1), 1-7. https://doi.org/10.1016/j.jcis.2018.09.053

Surfactant crystallisation is important in many applications in the food, consumer product and medical sectors. However, these processes are not well understood. In particular, surfactant crystallisation can be detrimental to the stability of deterge... Read More about Nuclear magnetic resonance and small-angle X-ray scattering studies of mixed sodium dodecyl sulfate and N,N-dimethyldodecylamine N-oxide aqueous systems performed at low temperatures.

Structural features and stability of Spanish sepiolite as a potential catalyst (2018)
Journal Article
Al-Ani, . A., Gertisser, R., & Zholobenko, V. (2018). Structural features and stability of Spanish sepiolite as a potential catalyst. Applied Clay Science, 297 -304. https://doi.org/10.1016/j.clay.2018.06.021

Abstract Sepiolite-based catalysts loaded with potassium hydroxide were prepared via the wet impregnation and ion-exchange methods and evaluated as catalysts in base-assisted reactions, such as transesterification of renewable oils. The structural fe... Read More about Structural features and stability of Spanish sepiolite as a potential catalyst.