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TCT-5 Safety and Efficacy of Postprocedural Anticoagulation After Primary Percutaneous Coronary Intervention for ST-Segment–Elevation Myocardial Infarction: A Meta-Analysis of RCTs (2024)
Journal Article
Elseidy, S., Vorla, M., Hamed, M., Rehan, M., Mohamad, T., Castiello, T., & Mamas, M. (2024). TCT-5 Safety and Efficacy of Postprocedural Anticoagulation After Primary Percutaneous Coronary Intervention for ST-Segment–Elevation Myocardial Infarction: A Meta-Analysis of RCTs. Journal of the American College of Cardiology, 84(18), B1-B438. https://doi.org/10.1016/j.jacc.2024.09.206

This study provides the first meta-analysis of randomized controlled trials (RCTs) to assess the safety and efficacy of postprocedural anticoagulation in STEMI patients.

TCT-931 Outcomes of Self-Expanding vs Balloon-Expandable Transcatheter Aortic Valves in Patients With Small Aortic Annuli: A Meta-analysis (2024)
Journal Article
Elseidy, S., Vorla, M., Hamed, M., Rehan, M., Isaac, J., Mohamad, T., …Mamas, M. (2024). TCT-931 Outcomes of Self-Expanding vs Balloon-Expandable Transcatheter Aortic Valves in Patients With Small Aortic Annuli: A Meta-analysis. Journal of the American College of Cardiology, 84(18), B1-B438. https://doi.org/10.1016/j.jacc.2024.09.1118

Background
Despite the benefits of TAVR, there is a lack of head-to-head comparison between different types of transcatheter aortic valves in patients with small aortic annulus essential to guide clinical decisions and improve patient outcomes in th... Read More about TCT-931 Outcomes of Self-Expanding vs Balloon-Expandable Transcatheter Aortic Valves in Patients With Small Aortic Annuli: A Meta-analysis.

Preparing for responsive management versus preparing for renal dialysis in multimorbid older people with advanced chronic kidney disease (Prepare for Kidney Care): Study protocol for a randomised controlled trial. (2024)
Journal Article
Worthington, J., Soundy, A., Frost, J., Rooshenas, L., MacNeill, S. J., Realpe Rojas, A., …Caskey, F. J. (2024). Preparing for responsive management versus preparing for renal dialysis in multimorbid older people with advanced chronic kidney disease (Prepare for Kidney Care): Study protocol for a randomised controlled trial. Trials, 25(1), 1-19. https://doi.org/10.1186/s13063-024-08509-8

Background: Chronic kidney disease (CKD) prevalence is steadily increasing, in part due to increased multimorbidity in our aging global population. When progression to kidney failure cannot be avoided, people need unbiased information to inform decis... Read More about Preparing for responsive management versus preparing for renal dialysis in multimorbid older people with advanced chronic kidney disease (Prepare for Kidney Care): Study protocol for a randomised controlled trial..

Takotsubo Syndrome: An International Expert Consensus Report on Practical Challenges and Specific Conditions (Part-1: Diagnostic and Therapeutic Challenges). (2024)
Journal Article
Yalta, K., Madias, J. E., Kounis, N. G., Y-Hassan, S., Polovina, M., Altay, S., …Seferovic, P. M. (in press). Takotsubo Syndrome: An International Expert Consensus Report on Practical Challenges and Specific Conditions (Part-1: Diagnostic and Therapeutic Challenges). Balkan Medical Journal, 41(6), 421-441. https://doi.org/10.4274/balkanmedj.galenos.2024.2024-9-98

In the recent years, there has been a burgeoning interest in Takotsubo syndrome (TTS), which is renowned as a specific form of reversible myocardial dysfunction. Despite the extensive literature available on TTS, clinicians still face several practic... Read More about Takotsubo Syndrome: An International Expert Consensus Report on Practical Challenges and Specific Conditions (Part-1: Diagnostic and Therapeutic Challenges)..

Takotsubo Syndrome: An International Expert Consensus Report on Practical Challenges and Specific Conditions (Part-2: Specific Entities, Risk Stratification and Challenges After Recovery). (2024)
Journal Article
Yalta, K., Madias, J. E., Kounis, N. G., Y-Hassan, S., Polovina, M., Altay, S., …Seferovic, P. M. (in press). Takotsubo Syndrome: An International Expert Consensus Report on Practical Challenges and Specific Conditions (Part-2: Specific Entities, Risk Stratification and Challenges After Recovery). Balkan Medical Journal, 41(6), 442-457. https://doi.org/10.4274/balkanmedj.galenos.2024.2024-9-99

Takotsubo syndrome (TTS) still remains as an enigmatic phenomenon. In particular, long-term challenges (including clinical recurrence and persistent symptoms) and specific entities in the setting of TTS have been the evolving areas of interest. On th... Read More about Takotsubo Syndrome: An International Expert Consensus Report on Practical Challenges and Specific Conditions (Part-2: Specific Entities, Risk Stratification and Challenges After Recovery)..

Pre‐hospital transdermal glyceryl trinitrate for transient ischaemic attack: Data from the RIGHT ‐2 trial (2024)
Journal Article
Appleton, J. P., Dixon, M., Woodhouse, L. J., Anderson, C. S., Ankolekar, S., Cala, L., …Bath, P. M. (in press). Pre‐hospital transdermal glyceryl trinitrate for transient ischaemic attack: Data from the RIGHT ‐2 trial. European Journal of Neurology, 31(11), 1-7. https://doi.org/10.1111/ene.16502

Background and purpose: Ambulance trials assessing interventions in suspected stroke patients will recruit patients with currently active symptoms that will resolve into transient ischaemic attack (TIA). The safety and efficacy of glyceryl trinitrate... Read More about Pre‐hospital transdermal glyceryl trinitrate for transient ischaemic attack: Data from the RIGHT ‐2 trial.

Flavonoids, gut microbiota and cardiovascular disease: Dynamics and interplay (2024)
Journal Article
Mansour, H., Slika, H., Nasser, S. A., Pintus, G., Khachab, M., Sahebkar, A., & Eid, A. H. (in press). Flavonoids, gut microbiota and cardiovascular disease: Dynamics and interplay. Pharmacological Research, 209(November 2024), 1-13. https://doi.org/10.1016/j.phrs.2024.107452

Cardiovascular disease (CVD) remains the leading cause of global morbidity and mortality. Extensive efforts have been invested to explicate mechanisms implicated in the onset and progression of CVD. Besides the usual suspects as risk factors (obesity... Read More about Flavonoids, gut microbiota and cardiovascular disease: Dynamics and interplay.

Ischemic Heart Disease in the Cancer Population: Trends, Outcomes, Epidemiology, and Challenges in Diagnosis and Treatment. (2024)
Journal Article
Condurache, D.-G., Raisi-Estabragh, Z., Ghosh, A. K., & Mamas, M. A. (in press). Ischemic Heart Disease in the Cancer Population: Trends, Outcomes, Epidemiology, and Challenges in Diagnosis and Treatment. Cardiology Clinics, 43(1), 57-67. https://doi.org/10.1016/j.ccl.2024.08.001

Patients with cancer are at increased risk of ischemic heart disease (IHD). The increased risk of IHD in these patients is due to the interaction of shared risk factors, cancer type and stage, and immuno/chemotherapy and radiotherapy regimens. Manage... Read More about Ischemic Heart Disease in the Cancer Population: Trends, Outcomes, Epidemiology, and Challenges in Diagnosis and Treatment..

Optimising inhaled therapy for patients with asthma. (2024)
Journal Article
Bansal, A., Franklin, L., & Twohig, H. (in press). Optimising inhaled therapy for patients with asthma. BMJ, 386, 1-6. https://doi.org/10.1136/bmj-2024-080353

What you need to know
Sub-optimally controlled asthma is common, in part because of normalisation of symptoms, underuse of preventer therapy, overuse of reliever therapy, and poor inhaler technique. Ensuring patients are using the right inhaled medi... Read More about Optimising inhaled therapy for patients with asthma..

Optical attenuation coefficient-based automatic segmentation of limbal epithelium and age-related differences (2024)
Conference Proceeding
Zhang, Y., Dimmock, R., Yang, Y., & Huang, Z. (2024). Optical attenuation coefficient-based automatic segmentation of limbal epithelium and age-related differences. In 2024 IEEE Ultrasonics, Ferroelectrics, and Frequency Control Joint Symposium (UFFC-JS) (1-4). https://doi.org/10.1109/uffc-js60046.2024.10793631

The limbus, located at the cornea-conjunctiva junction, houses limbal epithelial stem cells that maintain the corneal epithelium and respond to tissue damage. The limbal epithelial thickness is an indicator of corneal structural or functional alterat... Read More about Optical attenuation coefficient-based automatic segmentation of limbal epithelium and age-related differences.

Incidence of psoriatic arthritis in a UK primary care psoriasis population. (2024)
Journal Article
Rudge, A., Brown, S. T., Ransom, M., Helliwell, P. S., Packham, J., Tillett, W., …McHugh, N. J. (2024). Incidence of psoriatic arthritis in a UK primary care psoriasis population. The Journal of Rheumatology, 51(9), Article jrheum.2024-0556. https://doi.org/10.3899/jrheum.2024-0556

To determine the annual incidence of psoriatic arthritis in a UK primary care population with preexisting psoriasis followed prospectively over two years after excluding baseline prevalence of existing disease. TUDOR (Total bUrDen of psORiasis) was a... Read More about Incidence of psoriatic arthritis in a UK primary care psoriasis population..

Short‐term risk of cardiovascular events in people newly diagnosed with gout (2024)
Journal Article
Cipolletta, E., Nakafero, G., Richette, P., Avery, A. J., Mamas, M. A., Tata, L. J., & Abhishek, A. (in press). Short‐term risk of cardiovascular events in people newly diagnosed with gout. Arthritis & Rheumatology, https://doi.org/10.1002/art.42986

ObjectivesTo investigate the temporal association between first diagnosis of gout and cardiovascular events in the short‐term.MethodsWe performed a self‐controlled case series analysis and a cohort study using data from linked primary care, hospitali... Read More about Short‐term risk of cardiovascular events in people newly diagnosed with gout.

Interventions to promote colorectal cancer screening among people with a family history of colorectal cancer: A scoping review. (2024)
Journal Article
Firzara, A. M. T., Beh, H. C., Selvaraj, C. S., Mallen, C., Ng, C. J., & Lee, Y. K. (in press). Interventions to promote colorectal cancer screening among people with a family history of colorectal cancer: A scoping review. Preventive Medicine, 189(December 2024), 1-18. https://doi.org/10.1016/j.ypmed.2024.108137

The global incidence of colorectal cancer (CRC) is rising, with people having a family history of CRC (PFH-CRC) facing double the risk compared to the average-risk population. Despite this, CRC screening uptake among PFH-CRC remains low. There is a l... Read More about Interventions to promote colorectal cancer screening among people with a family history of colorectal cancer: A scoping review..

Sacroiliac joint pain: what treatment and when. (2024)
Journal Article
Cocconi, F., Maffulli, N., Bell, A., Memminger, M. K., Simeone, F., & Migliorini, F. (in press). Sacroiliac joint pain: what treatment and when. Expert Review of Neurotherapeutics, 1-8. https://doi.org/10.1080/14737175.2024.2400682

Spinal and non-spinal pathologies can cause low back pain. Non-spinal sources of low back pain include the sacroiliac joint (SIJ) and the hip. SIJ pain can be treated either conservatively or surgically. Current strategies for managing sacroiliac joi... Read More about Sacroiliac joint pain: what treatment and when..

Temporal Trends of Infant Mortality Secondary to Congenital Heart Disease: National CDC Cohort Analysis (1999–2020) (2024)
Journal Article
Chobufo, M., Ali, S., Taha, A., Duhan, S., Patel, N., Gonuguntla, K., …Balla, S. (2024). Temporal Trends of Infant Mortality Secondary to Congenital Heart Disease: National CDC Cohort Analysis (1999–2020). Birth Defects Research, 116(9), 1-8. https://doi.org/10.1002/bdr2.2398

Background
Infant mortality continues to be a significant problem for patients with congenital heart disease (CHD). Limited data exist on the recent trends of mortality in infants with CHD.

Methods
The CDC WONDER (Centers for Disease Control and... Read More about Temporal Trends of Infant Mortality Secondary to Congenital Heart Disease: National CDC Cohort Analysis (1999–2020).

Pharmacological management of secondary chronic spinal cord injury: a systematic review (2024)
Journal Article
Migliorini, F., Cocconi, F., Schäfer, L., Simeone, F., Jeyaraman, M., & Maffulli, N. (2024). Pharmacological management of secondary chronic spinal cord injury: a systematic review. British Medical Bulletin, 151(1), 49–68. https://doi.org/10.1093/bmb/ldae009

Introduction Spinal cord injury (SCI) may bring lifelong consequences for affected patients and a high financial burden to the health care system. Source of data Published peer-reviewed scientific articles identified from EMBASE, Google Scholar, PubM... Read More about Pharmacological management of secondary chronic spinal cord injury: a systematic review.

Metamizole in the Management of Musculoskeletal Disorders: Current Concept Review (2024)
Journal Article
Jeyaraman, N., Migliorini, F., Murugan, S., Ramasubramanian, S., Balaji, S., Maffulli, N., & Jeyaraman, M. (in press). Metamizole in the Management of Musculoskeletal Disorders: Current Concept Review. Journal of Clinical Medicine, 13(16), Article 4794. https://doi.org/10.3390/jcm13164794

Metamizole, or dipyrone, has been used for decades as a non-narcotic analgesic, providing pain relief from musculoskeletal disorders and antipyretic and antispasmolytic properties. Despite being in use since the 1920s, its mechanism of action still n... Read More about Metamizole in the Management of Musculoskeletal Disorders: Current Concept Review.

The prognostic value of mean platelet volume in patients with coronary artery disease: An updated systematic review with meta-analyses. (2024)
Journal Article
Galimzhanov, A., Tun, H. N., Sabitov, Y., Perone, F., Kursat, T. M., Tenekecioglu, E., & Mamas, M. A. (in press). The prognostic value of mean platelet volume in patients with coronary artery disease: An updated systematic review with meta-analyses. European Journal of Clinical Investigation, Article e14295. https://doi.org/10.1111/eci.14295

Mean platelet volume (MPV) is a widely available laboratory index, however its prognostic significance in patients with coronary artery disease (CAD) is still unclear. We intended to investigate and pool the evidence on the prognostic utility of admi... Read More about The prognostic value of mean platelet volume in patients with coronary artery disease: An updated systematic review with meta-analyses..