Worth the paper it's written on- A cross-sectional study of Medical Certificate of Stillbirth accuracy in the UK (2022)
Journal Article
Rimmer, M. P., Henderson, I., Parry-Smith, W., Raglan, O., Tamblyn, J., Heazell, A. E. P., Higgins, L. E., & working group, T. U. N. (2023). Worth the paper it's written on- A cross-sectional study of Medical Certificate of Stillbirth accuracy in the UK. International Journal of Epidemiology, 52(1), 295–308. https://doi.org/10.1093/ije/dyac100

Background
The Medical Certificate of Stillbirth (MCS) records data about a baby’s death after 24 weeks of gestation but before birth. Major errors that could alter interpretation of the MCS were widespread in two UK-based regional studies.

Metho... Read More about Worth the paper it's written on- A cross-sectional study of Medical Certificate of Stillbirth accuracy in the UK.

Development and psychometric evaluation of a patient reported outcome measure for polymyalgia rheumatica (2022)
Thesis
Twohig, H. J. Development and psychometric evaluation of a patient reported outcome measure for polymyalgia rheumatica. (Thesis). Keele University. https://keele-repository.worktribe.com/output/422679

Background
Polymyalgia rheumatica (PMR) causes pain, stiffness and disability in older adults. Measuring the impact of the condition from the patient’s perspective is vital to highquality research and patient-centred care, yet there are no validated... Read More about Development and psychometric evaluation of a patient reported outcome measure for polymyalgia rheumatica.

Aerobic exercise to improve cardiorespiratory function in Parkinson's (2021)
Thesis
Aburub, A. Aerobic exercise to improve cardiorespiratory function in Parkinson's. (Thesis). Keele University. https://keele-repository.worktribe.com/output/421300

Introduction
Cardiopulmonary impairments are the leading cause of morbidity and mortality in advanced stages of Parkinson’s. Although there is some evidence of pulmonary impairments in the earlier stages, symptoms remain asymptomatic until advanced... Read More about Aerobic exercise to improve cardiorespiratory function in Parkinson's.

Developing a 3D tissue-engineered model to study the biology and treatment of atherosclerosis (2021)
Thesis
Echrish, J. H. J. Developing a 3D tissue-engineered model to study the biology and treatment of atherosclerosis. (Thesis). Keele University. https://keele-repository.worktribe.com/output/421737

Coronary heart disease is the primary global cause of morbidity and mortality, accounting for about 33% of global deaths in 2013. Atherosclerosis is the principal cause of coronary heart disease and is caused by inflammation of the arterial wall. Thi... Read More about Developing a 3D tissue-engineered model to study the biology and treatment of atherosclerosis.

Automated Check-in Data Collection (AC DC): an investigation of utility, acceptability and effectiveness in general practice (2021)
Thesis
Lawton, S. A. Automated Check-in Data Collection (AC DC): an investigation of utility, acceptability and effectiveness in general practice. (Thesis). Keele University. https://keele-repository.worktribe.com/output/421298

Background: There are a range of data collection methodologies employed for collecting patient health related research data. Within primary care settings, and particularly within general practice, time and resources are limited. The utility of an aut... Read More about Automated Check-in Data Collection (AC DC): an investigation of utility, acceptability and effectiveness in general practice.

Examining the potential of general practice to support young people with self-harm behaviour: a systematic review and qualitative study (2021)
Thesis
Mughal, F. H. Examining the potential of general practice to support young people with self-harm behaviour: a systematic review and qualitative study. (Thesis). Keele University. https://keele-repository.worktribe.com/output/420345

Self-harm in young people is a national priority. General practitioners see young people who self-harm the most often in the National Health Service (NHS), and episodes of self-harm in young people presenting to general practice are rising. General p... Read More about Examining the potential of general practice to support young people with self-harm behaviour: a systematic review and qualitative study.

Investigating the impact of subchondral bone health and activity levels on cartilage repair in the knee (2021)
Thesis
Hopkins, T. Investigating the impact of subchondral bone health and activity levels on cartilage repair in the knee. (Thesis). Keele University. https://keele-repository.worktribe.com/output/419497

Damage to the articular cartilage (AC) in the human knee, caused by physical trauma or degenerative disease, represents a common and complex clinical problem. AC has a very limited capacity for self-repair and, once damaged, rarely heals spontaneousl... Read More about Investigating the impact of subchondral bone health and activity levels on cartilage repair in the knee.

Evaluation of surgical outcomes using administrative hospital data (2021)
Thesis
El-Dhuwaib, Y. Evaluation of surgical outcomes using administrative hospital data. (Thesis). Keele University. https://keele-repository.worktribe.com/output/419487

Hospital Episode Statistics (HES) is the main hospital administrative dataset in England. Since the early 1990s HES has been used for research. The aim of the thesis is to evaluate the use of HES data to measure surgical outcomes.

Objectives:
1.... Read More about Evaluation of surgical outcomes using administrative hospital data.

The association between osteoarthritis and invasive management strategies and clinical outcomes following acute myocardial infarction in electronic health record data (2020)
Thesis
Parmar, S. S. The association between osteoarthritis and invasive management strategies and clinical outcomes following acute myocardial infarction in electronic health record data. (Thesis). Keele University. https://keele-repository.worktribe.com/output/418969

Background
The association between osteoarthritis (OA) and acute myocardial infarction (AMI) is unclear, as are the outcomes of people with OA diagnosed with AMI. This study aimed to describe the annual prevalence of OA among AMI patients and descri... Read More about The association between osteoarthritis and invasive management strategies and clinical outcomes following acute myocardial infarction in electronic health record data.

Exploration of the use of decision analytic modelling in low back pain and sciatica (2020)
Thesis
Ashwell Hall, J. Exploration of the use of decision analytic modelling in low back pain and sciatica. (Thesis). Keele University. https://keele-repository.worktribe.com/output/417289

Low back pain (LBP) is a global public health problem. Keele University developed the STarT Back tool to stratify LBP patients according to their risk of persistent disability, matching treatments to individual risk. A 12-month trial-based economic e... Read More about Exploration of the use of decision analytic modelling in low back pain and sciatica.

Collaborative behaviours and professional culture traits in real-time interprofessional clinical simulation (2020)
Thesis
Berry, J. D. Collaborative behaviours and professional culture traits in real-time interprofessional clinical simulation. (Thesis). Keele University. https://keele-repository.worktribe.com/output/416230

Interprofessional education (IPE) has been proposed as a method of creating a collaborative practice ready workforce in healthcare. Postulated benefits of the technique include improving communication between professional groups, which in turn should... Read More about Collaborative behaviours and professional culture traits in real-time interprofessional clinical simulation.

Investigating comorbid mood disorders in people with inflammatory rheumatological conditions: a mixed methods study (2020)
Thesis
Machin, A. R. Investigating comorbid mood disorders in people with inflammatory rheumatological conditions: a mixed methods study. (Thesis). Keele University. https://keele-repository.worktribe.com/output/416229

Background
Mood problems in people with rheumatoid arthritis (RA) are under-recognised and treated, contributing to increased mortality. Comorbid depression is associated with increased disease activity and reduced quality of life (QoL), though the... Read More about Investigating comorbid mood disorders in people with inflammatory rheumatological conditions: a mixed methods study.

Understanding self-harm behaviour in older adults: a systematic review and qualitative study (2019)
Thesis
Troya Bermeo, M. I. Understanding self-harm behaviour in older adults: a systematic review and qualitative study. (Thesis). Keele University. https://keele-repository.worktribe.com/output/415218

Two worldwide challenges served as a drive for this research: the reality of an ageing population and the identified need of supporting people who self-harm. Addressing self-harm has been increasingly prioritised due to its social, economic and healt... Read More about Understanding self-harm behaviour in older adults: a systematic review and qualitative study.

A urinary proteomics investigation of pregnancy-related complications (2019)
Thesis
Al-Jasim, W. F. A urinary proteomics investigation of pregnancy-related complications. (Thesis). Keele University. https://keele-repository.worktribe.com/output/414917

Pre-eclampsia (PE) and intrauterine growth restriction (IUGR) are common disorders associated with placental implantation abnormalities in early pregnancy. Both conditions are heterogeneous, having complex and multiple aetiologies. PE complicates 5-8... Read More about A urinary proteomics investigation of pregnancy-related complications.

Use of invasive strategies in the management of non-ST elevation acute myocardial infarction and clinical outcomes (2019)
Thesis
Rashid, M. Use of invasive strategies in the management of non-ST elevation acute myocardial infarction and clinical outcomes. (Thesis). Keele University. https://keele-repository.worktribe.com/output/414984

Non-elevation acute myocardial infarction (NSTEMI) is one of the commonest phenotype of acute coronary syndrome (ACS) and associated with significant morbidity and mortality at the short and long term. An invasive strategy in the form of coronary ang... Read More about Use of invasive strategies in the management of non-ST elevation acute myocardial infarction and clinical outcomes.

Environmental ultraviolet-B exposures and measured health outcomes in English children (2019)
Thesis
Walker, J. Environmental ultraviolet-B exposures and measured health outcomes in English children. (Thesis). Keele University. https://keele-repository.worktribe.com/output/417800

Purpose
Vitamin D status has been shown to significantly impact extra-skeletal health outcomes. In the UK, the ability of the population to synthesize vitamin D is highly sensitive to environmental factors including ultraviolet-B wavelength light. T... Read More about Environmental ultraviolet-B exposures and measured health outcomes in English children.

Exploring the erythrocyte invasion–blocking effect of modified heparin and heparin mimetics in the human malaria parasite Plasmodium falciparum (2019)
Thesis
Hmoud, M. K. Exploring the erythrocyte invasion–blocking effect of modified heparin and heparin mimetics in the human malaria parasite Plasmodium falciparum. (Thesis). Keele University. https://keele-repository.worktribe.com/output/414945

Despite the efforts in malaria eradication and elimination, malaria still poses a global challenge to health that, through the spread of antimalarial resistance, highlights an urgent need for new approaches for malaria treatment. Heparin and sulphate... Read More about Exploring the erythrocyte invasion–blocking effect of modified heparin and heparin mimetics in the human malaria parasite Plasmodium falciparum.

Applied statistical methods for prediction modelling of upper limb functional recovery after stroke (2019)
Thesis
Al-Shallawi, A. N. S. Applied statistical methods for prediction modelling of upper limb functional recovery after stroke. (Thesis). Keele University. https://keele-repository.worktribe.com/output/414444

Stroke is the third largest cause of death in the world, with a significant contribution to disability. Motor function impairment, encompassing upper limb impairment, is the most significant post-stroke impairment. Such an impairment contributes to r... Read More about Applied statistical methods for prediction modelling of upper limb functional recovery after stroke.

Advancing cartilage cell therapy through chondrocyte culture and patient reported outcome measures (PROMs) (2019)
Thesis
Sykes, J. G. Advancing cartilage cell therapy through chondrocyte culture and patient reported outcome measures (PROMs). (Thesis). Keele University. https://keele-repository.worktribe.com/output/414327

Autologous chondrocyte implantation (ACI) is the only UK approved cell therapy or knee cartilage defects which might otherwise progress to osteoarthritis. For ACI, chondrocytes isolated from a healthy cartilage biopsy are expanded in number prior to... Read More about Advancing cartilage cell therapy through chondrocyte culture and patient reported outcome measures (PROMs).

A pilot study to identify serum biomarkers for post-stroke spasticity and related skeletal muscle changes (2019)
Thesis
Wasif, A. M. A pilot study to identify serum biomarkers for post-stroke spasticity and related skeletal muscle changes. (Thesis). Keele University. https://keele-repository.worktribe.com/output/414326

Spasticity is a common sensory-motor dysfunction observed following a stroke, and it is one of the signs indicating damage to the upper motor neurone system at the spinal or cerebral level. Stroke survivors often experience Some resistance to passive... Read More about A pilot study to identify serum biomarkers for post-stroke spasticity and related skeletal muscle changes.